대한예방한의학회지 (Journal of Society of Preventive Korean Medicine)

대한예방한의학회 (Society of Preventive Korean Medicine)
권호 표지

석류농축액의 광노화에 의한 주름 개선 효과

Effect of pomegranate concentration solution on photoaging

  • 강수진 (대구한의대학교 한의과대학 예방의학교실) ;
  • 최범락 ((주)건강사랑 연구소) ;
  • 김승희 ((주)건강사랑 연구소) ;
  • 이해연 ((주)건강사랑 연구소) ;
  • 박혜림 ((주)건강사랑 연구소) ;
  • 송창현 (대구한의대학교 방제과학글로벌연구센터) ;
  • 박수진 (대구한의대학교 방제과학글로벌연구센터) ;
  • 구세광 (대구한의대학교 방제과학글로벌연구센터) ;
  • 이영준 (대구한의대학교 한의과대학 예방의학교실)
  • Kang, Su Jin (Department of Preventive Medicine, College of Korean Medicine, Daegu Haany University) ;
  • Choi, Beom Rak (Research Institute, Health-Love Co., Ltd.) ;
  • Kim, Seung Hee (Research Institute, Health-Love Co., Ltd.) ;
  • Yi, Hae Yeon (Research Institute, Health-Love Co., Ltd.) ;
  • Park, Hye Rim (Research Institute, Health-Love Co., Ltd.) ;
  • Song, Chang Hyun (Medical Research Center for Globalization of Herbal Formulation, Daegu Haany University) ;
  • Park, Soo Jin (Medical Research Center for Globalization of Herbal Formulation, Daegu Haany University) ;
  • Ku, Sae Kwang (Medical Research Center for Globalization of Herbal Formulation, Daegu Haany University) ;
  • Lee, Young Joon (Department of Preventive Medicine, College of Korean Medicine, Daegu Haany University)
  • 투고 : 2015.03.31
  • 심사 : 2015.04.03
  • 발행 : 2015.04.30
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초록

Objective : Solar ultraviolet (UV) light can cause photoaging of human skin. Many researchers have focused on effective prevention to mitigate the aging process. This study was aimed to investigate anti-wrinkle effects of pomegranate concentration solution (PCS) using photoaged hairless mouse model. Method : To clarify the protective effect of PCS against UVB-induced photo-damage, water capacity was measured with transepidermal water loss (TEWL) in SKH-1 hairless mice. In addition, image of skin replicas was analyzed. Results : Our results showed that the PCS treatment protects skin against UVB-induced photoaging, based on the parameters including moisture capacity and TEWL. According to visual assessment of skin replica, application of 1 ml/kg PCS inhibited UV-induced wrinkle formation in mice skin as compared to the vehicle-applied control mice. Conclusion : Taken together, these results indicated that PCS could improve skin wrinkle formation induced by UVB irradiation in SHK-1 hairless mice. PCS could be applied as an anti-wrinkle agent.

키워드

참고문헌

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