Restorative Dentistry and Endodontics

The Korean Academy of Conservative Dentistry (대한치과보존학회)
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Antimicrobial effect of calcium hydroxide as an intracanal medicament in root canal treatment: a literature review - Part II. in vivo studies

  • Kim, Dohyun (Microscope Center, Department of Conservative Dentistry and Oral Science Research Center, Yonsei University College of Dentistry) ;
  • Kim, Euiseong (Microscope Center, Department of Conservative Dentistry and Oral Science Research Center, Yonsei University College of Dentistry)
  • Received : 2014.06.25
  • Accepted : 2014.10.15
  • Published : 2015.05.30
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Abstract

The first part of this study reviewed the characteristics of calcium hydroxide ($Ca(OH)_2$) and summarized the results of in vitro studies related to its antimicrobial effects. The second part of this review covers in vivo studies including human clinical studies and animal studies. The use of $Ca(OH)_2$ as an intracanal medicament represented better histological results in animal studies. However, human clinical studies showed limited antimicrobial effects that microorganisms were reduced but not eliminated through the treatment, and that some species had resistance to $Ca(OH)_2$. Most of clinical outcome studies supported that there is no improvement in healing of periapical lesions when $Ca(OH)_2$ was applied between appointments. Further studies are required for the antimicrobial effects of $Ca(OH)_2$, and search for the ideal material and technique to completely clean infected root canals should be continued.

Keywords

References

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