Journal of Korean Neurosurgical Society

The Korean Neurosurgical Society (대한신경외과학회)
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Pediatric Stroke

  • Jeong, Goun (Department of Pediatrics, Cheil General Hospital and Women's Healthcare Center, Dankook University College of Medicine) ;
  • Lim, Byung Chan (Department of Pediatrics, Seoul National University Children's Hospital, Seoul National University College of Medicine) ;
  • Chae, Jong-Hee (Department of Pediatrics, Seoul National University Children's Hospital, Seoul National University College of Medicine)
  • Received : 2015.04.21
  • Accepted : 2015.05.29
  • Published : 2015.06.28
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Abstract

Pediatric stroke is relatively rare but may lead to significant morbidity and mortality. Along with the advance of brain imaging technology and clinical awareness, diagnosis of pediatric stroke is increasing wordwide. Pediatric stroke differs from adults in variable risk factor/etiologies, diverse and nonspecific clinical presentation depending on ages. This review will be discussed pediatric stroke focusing on their clinical presentations, diagnosis and etiologies/risk factors.

Keywords

References

  1. Bowers KJ, Deveber GA, Ferriero DM, Roach ES, Vexler ZS, Maria BL : Cerebrovascular disease in children : recent advances in diagnosis and management. J Child Neurol 26 : 1074-1100, 2011 https://doi.org/10.1177/0883073811413585
  2. Cárdenas JF, Rho JM, Kirton A : Pediatric stroke. Childs Nerv Syst 27 : 1375-1390, 2011 https://doi.org/10.1007/s00381-010-1366-9
  3. deVeber G, Roach ES, Riela AR, Wiznitzer M : Stroke in children : recognition, treatment, and future directions. Semin Pediatr Neurol 7 : 309-317, 2000 https://doi.org/10.1053/spen.2000.20074
  4. Earley CJ, Kittner SJ, Feeser BR, Gardner J, Epstein A, Wozniak MA, et al. : Stroke in children and sickle-cell disease : Baltimore-Washington Cooperative Young Stroke Study. Neurology 51 : 169-176, 1998 https://doi.org/10.1212/WNL.51.1.169
  5. Freundlich CL, Cervantes-Arslanian AM, Dorfman DH : Pediatric stroke. Emerg Med Clin North Am 30 : 805-828, 2012 https://doi.org/10.1016/j.emc.2012.05.005
  6. Fullerton HJ, Wu YW, Sidney S, Johnston SC : Risk of recurrent childhood arterial ischemic stroke in a population-based cohort : the importance of cerebrovascular imaging. Pediatrics 119 : 495-501, 2007 https://doi.org/10.1542/peds.2006-2791
  7. Ganesan V, Prengler M, McShane MA, Wade AM, Kirkham FJ : Investigation of risk factors in children with arterial ischemic stroke. Ann Neurol 53 : 167-173, 2003 https://doi.org/10.1002/ana.10423
  8. Kissela BM, Khoury JC, Alwell K, Moomaw CJ, Woo D, Adeoye O, et al. : Age at stroke : temporal trends in stroke incidence in a large, biracial population. Neurology 79 : 1781-1787, 2012 https://doi.org/10.1212/WNL.0b013e318270401d
  9. Lee EH, Yum MS, Ko TS : Risk factors and clinical outcomes of childhood ischemic stroke in a single Korean tertiary care center. J Child Neurol 27 : 485-491, 2012 https://doi.org/10.1177/0883073811420297
  10. Lynch JK, Hirtz DG, DeVeber G, Nelson KB : Report of the National Institute of Neurological Disorders and Stroke workshop on perinatal and childhood stroke. Pediatrics 109 : 116-123, 2002 https://doi.org/10.1542/peds.109.1.116
  11. Mackay MT, Wiznitzer M, Benedict SL, Lee KJ, Deveber GA, Ganesan V; International Pediatric Stroke Study Group : Arterial ischemic stroke risk factors : the International Pediatric Stroke Study. Ann Neurol 69 : 130-140, 2011 https://doi.org/10.1002/ana.22224
  12. Meyer-Heim AD, Boltshauser E : Spontaneous intracranial haemorrhage in children : aetiology, presentation and outcome. Brain Dev 25 : 416-421, 2003 https://doi.org/10.1016/S0387-7604(03)00029-9
  13. Moharir M, Deveber G : Pediatric arterial ischemic stroke. Continuum (Minneap Minn) 20 (2 Cerebrovascular Disease) : 370-386, 2014
  14. Nelson KB, Lynch JK : Stroke in newborn infants. Lancet Neurol 3 : 150-158, 2004 https://doi.org/10.1016/S1474-4422(04)00679-9
  15. Per H, Unal E, Poyrazoglu HG, Ozdemir MA, Donmez H, Gumus H, et al. : Childhood stroke : results of 130 children from a reference center in Central Anatolia, Turkey. Pediatr Neurol 50 : 595-600, 2014 https://doi.org/10.1016/j.pediatrneurol.2013.12.023
  16. Rafay MF, Pontigon AM, Chiang J, Adams M, Jarvis DA, Silver F, et al. : Delay to diagnosis in acute pediatric arterial ischemic stroke. Stroke 40 : 58-64, 2009 https://doi.org/10.1161/STROKEAHA.108.519066
  17. Salih MA, Abdel-Gader AG, Al-Jarallah AA, Kentab AY, Gadelrab MO, Alorainy IA, et al. : Infectious and inflammatory disorders of the circulatory system as risk factors for stroke in Saudi children. Saudi Med J 27 Suppl 1 : S41-S52, 2006
  18. Salih MA, Al-Jarallah AS, Abdel-Gader AG, Al-Jarallah AA, Al-Saadi MM, Kentab AY, et al. : Cardiac diseases as a risk factor for stroke in Saudi children. Saudi Med J 27 Suppl 1 : S61-S68, 2006
  19. Salih MA, Murshid WR, Zahraa JN, Abdel-Gader AG, Al-Jarallah AA, Kentab AY, et al. : Congenital and genetic cerebrovascular anomalies as risk factors for stroke in Saudi children. Saudi Med J 27 Suppl 1 : S53-S60, 2006
  20. Shi KL, Wang JJ, Li JW, Jiang LQ, Mix E, Fang F, et al. : Arterial ischemic stroke : experience in Chinese children. Pediatr Neurol 38 : 186-190, 2008 https://doi.org/10.1016/j.pediatrneurol.2007.11.002
  21. Testai FD, Gorelick PB : Inherited metabolic disorders and stroke part 1 : Fabry disease and mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes. Arch Neurol 67 : 19-24, 2010
  22. Testai FD, Gorelick PB : Inherited metabolic disorders and stroke part 2 : homocystinuria, organic acidurias, and urea cycle disorders. Arch Neurol 67 : 148-153, 2010
  23. Tsze DS, Valente JH : Pediatric stroke : a review. Emerg Med Int 2011 : 734506, 2011
  24. Younkin DP : Diagnosis and treatment of ischemic pediatric stroke. Curr Neurol Neurosci Rep 2 : 18-24, 2002 https://doi.org/10.1007/s11910-002-0048-8

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