Journal of Integrative Natural Science (통합자연과학논문집)

The Basic Science Institute Chosun University (조선대학교 기초과학연구원)
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Biomimetic Catalysis in Ionic Liquids: Markedly Enhanced Enantioselectivity in Amino Acid-Catalyzed Directed Asymmetric Aldol Reactions

  • Yun, Suk-Jin (Department of Chemistry Education, Chosun University) ;
  • Lee, Jae Kwan (Department of Chemistry Education, Chosun University)
  • Received : 2015.04.29
  • Accepted : 2015.06.25
  • Published : 2015.06.30
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Abstract

Amino acid-catalyzed directed asymmetric aldol reactions showed enhanced enantioselectivity when conducted in ionic liquids. Optically active products were afforded in better yields (up to 23% higher) and enantiomeric excess (up to 21% higher) in ionic liquids than in conventional organic solvents.

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References

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