Journal of the East Asian Society of Dietary Life (동아시아식생활학회지)

The East Asian Society of Dietary Life (동아시아식생활학회)
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Reducing Effects of Black Rice (Oryza sativa L.) Extract on Body Fat Weight in Ovariectomized Rats

난소절제 흰쥐에서 흑미 호분층 추출물의 체지방 감소 효과

  • Lee, Young Min (Functional Food & Nutrition Division, Department of Agrofood Resources, National Academy of Agricultural Science, RDA) ;
  • Nam, Song Yee (Functional Food & Nutrition Division, Department of Agrofood Resources, National Academy of Agricultural Science, RDA) ;
  • Jang, Hwan Hee (Functional Food & Nutrition Division, Department of Agrofood Resources, National Academy of Agricultural Science, RDA) ;
  • Kim, Jung Bong (Functional Food & Nutrition Division, Department of Agrofood Resources, National Academy of Agricultural Science, RDA) ;
  • Kim, Haeng Ran (Functional Food & Nutrition Division, Department of Agrofood Resources, National Academy of Agricultural Science, RDA) ;
  • Lee, Hae-Jeung (Dept. of Food and Nutrition, Eulji University) ;
  • Lee, Sung-Joon (Dept. of Biotechnology, Graduate School of Life Sciences and Biotechnology, Korea University) ;
  • Park, Kye Won (Dept. of Food Science and Biotechnology, Sungkyunkwan University) ;
  • Lee, Sung Hyen (Functional Food & Nutrition Division, Department of Agrofood Resources, National Academy of Agricultural Science, RDA)
  • 이영민 (국립농업과학원 기능성식품과) ;
  • 남송이 (국립농업과학원 기능성식품과) ;
  • 장환희 (국립농업과학원 기능성식품과) ;
  • 김정봉 (국립농업과학원 기능성식품과) ;
  • 김행란 (국립농업과학원 기능성식품과) ;
  • 이해정 (을지대학교 식품영양학과) ;
  • 이성준 (고려대학교 식품공학과) ;
  • 박계원 (성균관대학교 식품생명공학과) ;
  • 이성현 (국립농업과학원 기능성식품과)
  • Received : 2015.05.12
  • Accepted : 2015.06.08
  • Published : 2015.06.30
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Abstract

Estrogen deficiency is associated with increased body weight and fat mass, resulting in obesity-associated complications such as insulin resistance, cardiovascular disease, and type-2 diabetes. The present study was performed to investigate the effect of black rice (Oryza sativa L.) extracts (BRE) on body weight and fat mass in ovariectomized rats. Ovariectomized (or sham-operated) rats were randomly blocked into three groups (n=8~10 per group): sham operated group (S), ovariectomized control group (OVX), and ovariectomized group with BRE 30 mg/kg B.W. (BRE). High fat diet (fat calories 45%) was fed to all experimental rats for 12 weeks. Final body weight, weight gain, and body fat weight showed significant increases in the OVX group, whereas they were reduced by BRE supplementation. Serum TAG, T-chol level, and adipocyte size were not significantly different among the three groups. However, ovariectomy-induced hepatic steatosis was improved in BRE-treated group. Moreover, in the BRE group, serum leptin levels was significantly lower and fecal total lipid concentrations was significantly higher compared to the OVX group. The gathered data suggest that BRE is a potentially useful ingredient to protect against estrogen deficiency-related obesity and its related diseases.

Keywords

References

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