한국콘텐츠학회논문지 (The Journal of the Korea Contents Association)

  • 제15권3호
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  • Pages.272-279
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  • 2015
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  • 1598-4877(pISSN)
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  • 2508-6723(eISSN)
한국콘텐츠학회 (The Korea Contents Association)
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단기간 귀리 추출물 섭취의 혈당 및 콜레스테롤 저하 효과 평가

Evaluation the Effects of Short Term Intake Avena sativa Extracts on Blood Glucose and Cholesterol Level

  • 김하나 (강원대학교 의학전문대학원 진단검사의학교실) ;
  • 이인수 (강원대학교 의학전문대학원 진단검사의학교실) ;
  • 신경숙 (강원대학교 의학전문대학원 진단검사의학교실) ;
  • 윤순규 (강원대학교 의학전문대학원 진단검사의학교실) ;
  • 이부형 (강원대학교 의학전문대학원 진단검사의학교실) ;
  • 윤승규 (강원대학교 의학전문대학원 진단검사의학교실) ;
  • 최진우 (강원대학교 의생명과학대학 의생명공학과) ;
  • 서인범 (강원대학교 의학전문대학원 진단검사의학교실)
  • 투고 : 2015.02.11
  • 심사 : 2015.02.21
  • 발행 : 2015.03.28
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초록

최근 혈당조절에 도움이 되는 다양한 천연추출물에 대한 연구가 진행되고 있다. 귀리는 다양한 생리효능이 있는 것으로 알려져 있는데 특히 ${\beta}$ 클루칸은 체내 혈중 콜레스테롤 수치를 낮추어 심혈관 질환을 예방하고 비만과 관련된 성인병 예방에 효과를 보이는 것으로 보고되고 있다. 이에 본 연구는 상품화된 귀리 추출물로 이루어진 다운앤컨트롤(비엠제약)을 이용하여 6주간 무작위, 이중맹검, 실험군-대조군 임상 연구를 통해 혈당 및 혈중 콜레스테롤에 대한 효과를 평가한 결과, 통계학적으로 유의한 차이를 보이지는 않았지만 당화알부민은 각각 시험군에서 50.33% 감소, 대조군에서 37.91% 감소 및 중성지방은 시험군에서 7.51% 감소, 대조군에서 3.98% 증가로 상대적으로 차이를 보여 시험약의 혈당저하 효과 및 중성지방의 감소효과를 일부에서 관찰할 수 있었다.

Recently, studies about various natural extracts to help control blood glucose has been in progress. Avena sativa is well known to have various physilogical effects. Especially, ${\beta}$-glucan has effect about lowering blood glucose level and prevent cardiovascular dz and adult dz related to obesity. In this study we evaluated the effect of Down and control (BM pharmaceutical) which is consist of commercialized Avena sativa fextracts on blood glucose and cholesterol, 6weeks, randomized, double-blind, placebo-controlled trials. The results show not significantly different in all blood index test group from control group, but in glycated albumin decreased 50.33% for test group, decreased 37.91% for control group, in triglyceride decreased 7.51% for test group, increased 3.98 for control group and we can observed Avena sativa has blood glucose and triglyceride lowering effect in some.

키워드

참고문헌

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