참고문헌
- Abramson HN (2011). The lipogenesis pathway as a cancer target. J Med Chem, 54, 5615-38. https://doi.org/10.1021/jm2005805
- Abu-Elheiga L, Matzuk MM, Abo-Hashema KA, et al (2001). Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2. Science, 291, 2613-6. https://doi.org/10.1126/science.1056843
- Bergstrand CG, Czar B (1956). Demonstration of a new protein fraction in serum from the human fetus. Scand J Clin Lab Invest, 8, 174. https://doi.org/10.3109/00365515609049266
- Bruix J, Sherman M (2011). Management of hepatocellular carcinoma: an update. Hepatology, 53, 1020-2. https://doi.org/10.1002/hep.24199
- Calvisi DF, Wang C, Ho C, et al (2011). Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma. Gastroenterology, 140, 1071-83. https://doi.org/10.1053/j.gastro.2010.12.006
- Chajes V, Cambot M, Moreau K, et al (2006). Acetyl-CoA carboxylase alpha is essential to breast cancer cell survival. Cancer Res, 66, 5287-94. https://doi.org/10.1158/0008-5472.CAN-05-1489
- Chamary JV, Parmley JL, Hurst LD (2006). Hearing silence: non-neutral evolution at synonymous sites in mammals. Nat Rev Genet, 7, 98-108. https://doi.org/10.1038/nrg1770
- Dorn C, Riener MO, Kirovski G, et al (2010). Expression of fatty acid synthase in nonalcoholic fatty liver disease. Int J Clin Exp Pathol, 3, 505-14.
- Eggert SL, Huyck KL, Somasundaram P, et al (2012). Genomewide linkage and association analyses implicate FASN in predisposition to uterine leiomyomata. Am J Hum Genet, 91, 621-8. https://doi.org/10.1016/j.ajhg.2012.08.009
- Furuta E, Okuda H, Kobayashi A, et al (2010). Metabolic genes in cancer: their roles in tumor progression and clinical implications. Biochim Biophys Acta, 1805, 141-52.
- Hanahan D, Weinberg RA (2011). Hallmarks of cancer: the next generation. Cell, 144, 646-74. https://doi.org/10.1016/j.cell.2011.02.013
- Hatzivassiliou G, Zhao F, Bauer DE, et al (2005). ATP citrate lyase inhibition can suppress tumor cell growth. Cancer Cell, 8, 311-21. https://doi.org/10.1016/j.ccr.2005.09.008
- Jemal A, Bray F, Center MM, et al (2011). Global cancer statistics. CA Cancer J Clin, 61, 69-90. https://doi.org/10.3322/caac.20107
- Jemal A, Siegel R, Xu J, et al (2010). Cancer statistics, 2010. CA Cancer J Clin, 60, 277-300. https://doi.org/10.3322/caac.20073
- Jin X, Zhang KJ, Guo X, et al (2014). Fatty Acid synthesis pathway genetic variants and clinical outcome of non-small cell lung cancer patients after surgery. Asian Pac J Cancer Prev, 15, 7097-103. https://doi.org/10.7314/APJCP.2014.15.17.7097
- Laing RE, Hess P, Shen Y, et al (2011). The role and impact of SNPs in pharmacogenomics and personalized medicine. Curr Drug Metab, 12, 460-86. https://doi.org/10.2174/138920011795495268
- Lettieri Barbato D, Vegliante R, Desideri E, et al (2014). Managing lipid metabolism in proliferating cells: new perspective for metformin usage in cancer therapy. Biochim Biophys Acta, 1845, 317-24.
- Lin DY, Lin SM, Liaw YF (1997). Non-surgical treatment of hepatocellular carcinoma. J Gastroenterol Hepatol, 12, 319-28. https://doi.org/10.1111/j.1440-1746.1997.tb00428.x
- Liu HB, Peng YP, Dou CW, et al (2012). Comprehensive study on associations between nine SNPs and glioma risk. Asian Pac J Cancer Prev, 13, 4905-8. https://doi.org/10.7314/APJCP.2012.13.10.4905
- Llovet JM, Bruix J (2003). Systematic review of randomized trials for unresectable hepatocellular carcinoma: Chemoembolization improves survival. Hepatology, 37, 429-42. https://doi.org/10.1053/jhep.2003.50047
- Llovet JM, Real MI, Montana X, et al (2002). Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial. Lancet, 359, 1734-9. https://doi.org/10.1016/S0140-6736(02)08649-X
- Mao J, DeMayo FJ, Li H, et al (2006). Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis. Proc Natl Acad Sci USA, 103, 8552-7. https://doi.org/10.1073/pnas.0603115103
- Mashima T, Seimiya H, Tsuruo T (2009). De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy. Br J Cancer, 100, 1369-72. https://doi.org/10.1038/sj.bjc.6605007
- Menendez JA, Lupu R (2007). Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis. Nat Rev Cancer, 7, 763-77. https://doi.org/10.1038/nrc2222
- Migita T, Ruiz S, Fornari A, et al (2009). Fatty acid synthase: a metabolic enzyme and candidate oncogene in prostate cancer. J Natl Cancer Inst, 101, 519-32. https://doi.org/10.1093/jnci/djp030
- Nguyen PL, Ma J, Chavarro JE, et al (2010). Fatty acid synthase polymorphisms, tumor expression, body mass index, prostate cancer risk, and survival. J Clin Oncol, 28, 3958-64. https://doi.org/10.1200/JCO.2009.27.0793
- Rysman E, Brusselmans K, Scheys K, et al (2010). De novo lipogenesis protects cancer cells from free radicals and chemotherapeutics by promoting membrane lipid saturation. Cancer Res, 70, 8117-26. https://doi.org/10.1158/0008-5472.CAN-09-3871
- Sell S (2008). Alpha-fetoprotein, stem cells and cancer: how study of the production of alpha-fetoprotein during chemical hepatocarcinogenesis led to reaffirmation of the stem cell theory of cancer. Tumour Biol, 29, 161-80. https://doi.org/10.1159/000143402
- Swinnen JV, Brusselmans K, Verhoeven G (2006). Increased lipogenesis in cancer cells: new players, novel targets. Curr Opin Clin Nutr Metab Care, 9, 358-65. https://doi.org/10.1097/01.mco.0000232894.28674.30
- Watson JA, Fang M, Lowenstein JM (1969). Tricarballylate and hydroxycitrate: substrate and inhibitor of ATP: citrate oxaloacetate lyase. Arch Biochem Biophys, 135, 209-17. https://doi.org/10.1016/0003-9861(69)90532-3
- Xing J, Myers RE, He X, et al (2011). GWAS-identified colorectal cancer susceptibility locus associates with disease prognosis. Eur J Cancer, 47, 1699-707. https://doi.org/10.1016/j.ejca.2011.02.004
- Yoon S, Lee MY, Park SW, et al (2007). Up-regulation of acetyl- CoA carboxylase alpha and fatty acid synthase by human epidermal growth factor receptor 2 at the translational level in breast cancer cells. J Biol Chem, 282, 26122-31. https://doi.org/10.1074/jbc.M702854200
- Yuan P, Wang S, Zhou F, et al (2014). Functional polymorphisms in the NPAS2 gene are associated with overall survival in transcatheter arterial chemoembolization-treated hepatocellular carcinoma patients. Cancer Sci, 105, 825-32. https://doi.org/10.1111/cas.12428
- Zaidi N, Royaux I, Swinnen JV, et al (2012a). ATP citrate lyase knockdown induces growth arrest and apoptosis through different cell- and environment-dependent mechanisms. Mol Cancer Ther, 11, 1925-35. https://doi.org/10.1158/1535-7163.MCT-12-0095
- Zaidi N, Royaux I, Swinnen JV, et al (2012a). ATP citrate lyase knockdown induces growth arrest and apoptosis through different cell- and environment-dependent mechanisms. Mol Cancer Ther, 11, 1925-35. https://doi.org/10.1158/1535-7163.MCT-12-0095
- Zhou F, He X, Liu H, et al (2012). Functional polymorphisms of circadian positive feedback regulation genes and clinical outcome of Chinese patients with resected colorectal cancer. Cancer, 118, 937-46. https://doi.org/10.1002/cncr.26348
- Zhou Y, Bollu LR, Tozzi F, et al (2013). ATP citrate lyase mediates resistance of colorectal cancer cells to SN38. Mol Cancer Ther, 12, 2782-91. https://doi.org/10.1158/1535-7163.MCT-13-0098
피인용 문헌
- ATP-citrate lyase vol.28, pp.2, 2017, https://doi.org/10.1097/MOL.0000000000000390