Asian Pacific Journal of Cancer Prevention

Asian Pacific Journal of Cancer Prevention (아시아태평양암예방학회)
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Characteristics of Oral Tongue and Base of the Tongue Cancer: A Hospital Cancer Registry Based Analysis

  • Krishnatreya, Manigreeva (Cancer Registry, Epidemiology and Biostatistics, Dr.B Borooah Cancer Institute) ;
  • Nandy, Pintu (Cancer Registry, Epidemiology and Biostatistics, Dr.B Borooah Cancer Institute) ;
  • Rahman, Tashnin (Head and Neck Oncology, Dr.B Borooah Cancer Institute) ;
  • Sharma, Jagannath Dev (Cancer Registry, Epidemiology and Biostatistics, Dr.B Borooah Cancer Institute) ;
  • Das, Anupam (Head and Neck Oncology, Dr.B Borooah Cancer Institute) ;
  • Kataki, Amal Chandra (Cancer Registry, Epidemiology and Biostatistics, Dr.B Borooah Cancer Institute) ;
  • Das, Ashok Kumar (Head and Neck Oncology, Dr.B Borooah Cancer Institute) ;
  • Das, Rajjjyoti (Head and Neck Oncology, Dr.B Borooah Cancer Institute)
  • Published : 2015.03.09
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Abstract

Background: Tongue cancer is one of the leading sites of cancer in our population. Aim: To evaluate the socio-demographic profiles and stages at diagnosis of oral tongue (OT) and base of tongue (BT) cancers, and identify any possible variations in characteristics. Materials and Methods: A retrospective analysis was conducted on tongue cancer cases, divided into OT and BT, registered at the hospital cancer registry of North-East India during January 2010 to May 2013. Cases were analyzed for age, gender, residential status and different levels of education for patients, the stage at diagnosis and presence of distant metastasis. Results: A total of 1,113 cases of tongue cancers were registered, 846(76.1%) of BT and 267(23.9%) of OT. While 33.9% of BT cancer patients were above 65 years of age, the figure for OT cancers was 18.4%, stages III and IV accounting for 90.8% and 77%, respectively. The relative risk for distant metastasis in OT cancers was 3.3 (95% CI 1.08-10.1, p=0.03). Conclusions: In the subsites of tongue cancers in our population, the majority arose from the base of tongue, these tending to occur in older individuals and presenting at late stage.

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References

  1. Ang KN, Harris J, Wheeler R, et al (2010). Human papillomavirus and survival of patients with oropharyngeal cancer. N Engl J Med, 363, 24-35. https://doi.org/10.1056/NEJMoa0912217
  2. Balaram P, Nalinakumari, KR, Abraham E, et al (1995). Human papillomavirus in 91 oral cancers from Indian betel quid chewers-high prevalence and multiplicity of infections. Int J Cancer, 61, 450-4. https://doi.org/10.1002/ijc.2910610403
  3. Chaturvedi AK (2014). Disparities in HPV-associated cancers. Paper presented at American Association for Cancer Research conference on the science of cancer health disparities, SA, Texas, USA
  4. Coelho KR (2012). Challenges of the oral cancer burden in India. J Cancer Epidemiol, 2012, 701932.
  5. D'Souza G, Gross ND, Pai SI, et al (2014). Oral human papillomavirus (HPV) infection in HPV-positive patients with oropharyngeal cancer and their partners. J Clin Oncol, 32, doi 10.1200/JCO.2014.55.1341
  6. Edge S, Byrd DR, Compton CC, et al (2010). AJCC Cancer Staging Manual. 7 th ed. Bangalore: Springer-Verlag.
  7. Elango KJ, Suresh A, Erode EM, et al (2011). Role of human papilloma virus in oral tongue squamous cell carcinoma. Asian Pac J Cancer Prev, 12, 889-96.
  8. Ferlay J, Soerjomataram I, Ervik M, et al (2014). GLOBOCON 2012: estimated cancer incidence, mortality and prevalence worldwide in 2012. IARC;WHO, Lyon. Available at http://globocan.iarc.fr
  9. Ferrari D, Codeca C, Fiore J, et al (2009). Biomolecular markers in cancer of the tongue. J Oncol, 2009, 412908
  10. Herrero R, Castellsague X, Pawlita M, et al (2003). Human papillomavirus and oral cancer: the international agency for research on cancer multicenter study. J Natl Cancer Inst, 95, 1772-83. https://doi.org/10.1093/jnci/djg107
  11. Kreimer AR, Clifford GM, Boyle P, Franceschi S (2005). Human papillomavirus types in head and neck squamous cell carcinomas worldwide: a systematic review. Cancer Epidemiol Biomarkers Prev, 14, 467-75. https://doi.org/10.1158/1055-9965.EPI-04-0551
  12. Krishnamurthy A, Ramshankar V (2013). Early stage oral tongue cancer among non-tobacco users - an increasing trend observed in a south Indian patient population presenting at a single centre. Asian Pac J Cancer Prev, 14, 5061-65 https://doi.org/10.7314/APJCP.2013.14.9.5061
  13. Krishnatreya M, Hoque N, Sharma JD, Kataki AC (2014). Comparative study on the pattern of tobacco related cancers and habits of tobacco usage amongst bengali muslim community of Barpeta District Assam, India. Int Res J Social Sci, 3, 22-4.
  14. Mahon SM (2000). The role of the nurse in developing cancer screening programs. Oncol Nurs Forum, 27, 19-27.
  15. National Cancer Registry Programme (2013).Three-year report of population based cancer registries:2009-2011. NCDIRICMR, Bangalore.
  16. Ramshankar V, Soundara VT, Shyamsundar V, Ramani P, Krishnamurthy A (2014). Risk stratification of early stage oral tongue cancers based on HPV status and p16 immunoexpression. Asian Pac J Cancer Prev, 15, 8351-59. https://doi.org/10.7314/APJCP.2014.15.19.8351
  17. Sutandyo N, Ramli R, Sari L, Soeis DS (2014). Profile and survival of tongue cancer patients in "Dharmais" cancer hospital, Jakarta. Asian Pac J Cancer Prev, 15, 1971-75. https://doi.org/10.7314/APJCP.2014.15.5.1971
  18. Vatanasapt P, Suwanrungruang K, Kamsa-ard S, Promthet S, Parkin DM (2011). Epidemiology of oral and pharyngeal cancers in Khon Kaen, Thailand: a high incidence in females. Asian Pac J Cancer Prev, 12, 2505-08.