Maxillofacial Plastic and Reconstructive Surgery

  • 제37권
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  • Pages.5.1-5.4
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  • 2015
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  • 2288-8101(pISSN)
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  • 2288-8586(eISSN)
대한악안면성형재건외과학회 (Korean Association of Maxillofacial Plastic and Reconstructive Surgeons)
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Microvascular autologous submandibular gland transplantation in severe cases of keratoconjunctivitis sicca

  • Su, Jia-Zeng (Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology) ;
  • Cai, Zhi-Gang (Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology) ;
  • Yu, Guang-Yan (Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology)
  • 투고 : 2015.01.12
  • 심사 : 2015.01.12
  • 발행 : 2015.12.31
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초록

Dry eye syndrome is a relatively common disease of the tears and ocular surfaces that results in discomfort, visual disturbance, and tear film instability with possible damage to the ocular surfaces. Microvascular submandibular gland (SMG) transfer offers a surgical alternative for a permanent autologous substitution of tears using the basal secretion of a transplanted SMG. Long-term follow-up reveals that this technique is a lasting and effective solution for patients with severe dry eye syndrome. The uncomfortable symptoms were relieved, and the frequency of use of pharmaceutical tear substitutes was reduced. Objective examination showed significant improvement in tear film and some features of ocular surface such as breakup time of tear film and corneal staining. Patients may suffer from obstruction of Wharton's duct or epiphora after surgery. Activation of secretion-related receptors could improve the early hypofunction of the denervated SMG and prevent the duct obstruction. Reduction surgery, partial SMG transplantation, uses of atropine gel or Botulinum toxin A could be the choices of treatment for epiphora.

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참고문헌

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  5. Free thyroid transfer: Short‐term results of a novel procedure to prevent post‐radiation hypothyroidism vol.39, pp.6, 2015, https://doi.org/10.1002/hed.24590
  6. Botulinum Toxin Conjugated With Silk Fibroin and 4-Hexylresorcinol vol.28, pp.4, 2015, https://doi.org/10.1097/scs.0000000000003763
  7. Current and emerging therapy of dry eye disease. Part B: non-pharmacological modalities vol.12, pp.4, 2017, https://doi.org/10.1080/17469899.2017.1344552
  8. Innovations in Treatment of Lagophthalmos and Exposure Keratopathy vol.57, pp.4, 2017, https://doi.org/10.1097/iio.0000000000000185
  9. Effect of Cosmetic Procedures in the Periorbital Area on the Organ of Vision: Overview vol.15, pp.3, 2015, https://doi.org/10.18008/1816-5095-2018-3-233-241
  10. Autonomic reinnervation and functional regeneration in autologous transplanted submandibular glands in patients with severe keratoconjunctivitis sicca vol.10, pp.2, 2015, https://doi.org/10.1038/s41368-018-0014-1