참고문헌
- Russ AP, Wattler S, Colledge WH et al (2000) Eomesodermin is required for mouse trophoblast development and mesoderm formation. Nature 404, 95-99 https://doi.org/10.1038/35003601
- Takahashi K and Yamanaka S (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126, 663-676 https://doi.org/10.1016/j.cell.2006.07.024
- Yu J, Vodyanik MA, Smuga-Otto K et al (2007) Induced pluripotent stem cell lines derived from human somatic cells. Science 318, 1917-1920 https://doi.org/10.1126/science.1151526
- Clarke MF and Fuller M (2006) Stem cells and cancer: two faces of eve. Cell 124, 1111-1115 https://doi.org/10.1016/j.cell.2006.03.011
- Dirks PB (2006) Cancer: stem cells and brain tumours. Nature 444, 687-688 https://doi.org/10.1038/444687a
- Pierce KL, Premont RT and Lefkowitz RJ (2002) Seventransmembrane receptors. Nat Rev Mol Cell Biol 3, 639-650 https://doi.org/10.1038/nrm908
- Dorsam RT and Gutkind JS (2007) G-protein-coupled receptors and cancer. Nat Rev Cancer 7, 79-94 https://doi.org/10.1038/nrc2069
- O'Hayre M, Degese MS and Gutkind JS (2014) Novel insights into G protein and G protein-coupled receptor signaling in cancer. Curr Opin Cell Biol 27, 126-135 https://doi.org/10.1016/j.ceb.2014.01.005
- Overington JP, Al-Lazikani B and Hopkins AL (2006) How many drug targets are there? Nat Rev Drug Discov 5, 993-996 https://doi.org/10.1038/nrd2199
- Takeda S, Kadowaki S, Haga T, Takaesu H and Mitaku S (2002) Identification of G protein-coupled receptor genes from the human genome sequence. FEBS Lett 520, 97-101 https://doi.org/10.1016/S0014-5793(02)02775-8
- Fredriksson R, Lagerstrom MC, Lundin LG and Schioth HB (2003) The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints. Mol Pharmacol 63, 1256-1272 https://doi.org/10.1124/mol.63.6.1256
- Gloriam DE, Fredriksson R and Schioth HB (2007) The G protein-coupled receptor subset of the rat genome. BMC Genomics 8, 338 https://doi.org/10.1186/1471-2164-8-338
- Taussig R, Iniguez-Lluhi JA and Gilman AG (1993) Inhibition of adenylyl cyclase by Gi alpha. Science 261, 218-221 https://doi.org/10.1126/science.8327893
- Hubbard KB and Hepler JR (2006) Cell signalling diversity of the Gqalpha family of heterotrimeric G proteins. Cell Signal 18, 135-150 https://doi.org/10.1016/j.cellsig.2005.08.004
- Sassone-Corsi P (2012) The cyclic AMP pathway. Cold Spring Harb Perspect Biol 4, 1-3 https://doi.org/10.1101/cshperspect.a011148
- Gutkind JS (1998) The pathways connecting G protein-coupled receptors to the nucleus through divergent mitogen-activated protein kinase cascades. J Biol Chem 273, 1839-1842 https://doi.org/10.1074/jbc.273.4.1839
- Han D, Kim HJ, Choi HY et al (2014) 3,2'-Dihydroxyflavone-treated Pluripotent Stem Cells Show Enhanced Proliferation, Pluripotency Markers Expression, and Neuroprotective Properties. Cell Transplant [Epub ahead of print].
- Jeon K, Oh HJ, Lim H et al (2012) Self-renewal of embryonic stem cells through culture on nanopattern polydimethylsiloxane substrate. Biomaterials 33, 5206-5220 https://doi.org/10.1016/j.biomaterials.2012.04.011
- Jeon K, Lim H, Kim JH et al (2012) Bax inhibitor-1 enhances survival and neuronal differentiation of embryonic stem cells via differential regulation of mitogen-activated protein kinases activities. Biochim Biophys Acta 1823, 2190-2200 https://doi.org/10.1016/j.bbamcr.2012.08.005
- Nakamura K, Salomonis N, Tomoda K, Yamanaka S and Conklin BR (2009) G(i)-coupled GPCR signaling controls the formation and organization of human pluripotent colonies. PLoS One 4, e7780 https://doi.org/10.1371/journal.pone.0007780
- Layden BT, Newman M, Chen F, Fisher A and Lowe WL Jr (2010) G protein coupled receptors in embryonic stem cells: a role for Gs-alpha signaling. PLoS One 5, e9105 https://doi.org/10.1371/journal.pone.0009105
- Callihan P, Mumaw J, Machacek DW, Stice SL and Hooks SB (2011) Regulation of stem cell pluripotency and differentiation by G protein coupled receptors. Pharmacol Ther 129, 290-306 https://doi.org/10.1016/j.pharmthera.2010.10.007
- Melchiorri D, Cappuccio I, Ciceroni C et al (2007) Metabotropic glutamate receptors in stem/progenitor cells. Neuropharmacology 53, 473-480 https://doi.org/10.1016/j.neuropharm.2007.05.031
- Cappuccio I, Spinsanti P, Porcellini A et al (2005) Endogenous activation of mGlu5 metabotropic glutamate receptors supports self-renewal of cultured mouse embryonic stem cells. Neuropharmacology 49 Suppl 1, 196-205 https://doi.org/10.1016/j.neuropharm.2005.05.014
- Cappuccio I, Verani R, Spinsanti P et al (2006) Contextdependent regulation of embryonic stem cell differentiation by mGlu4 metabotropic glutamate receptors. Neuropharmacology 51, 606-611 https://doi.org/10.1016/j.neuropharm.2006.05.007
- Ciceroni C, Mosillo P, Mastrantoni E et al (2010) mGLU3 metabotropic glutamate receptors modulate the differentiation of SVZ-derived neural stem cells towards the astrocytic lineage. Glia 58, 813-822
- Schwirtlich M, Emri Z, Antal K, Mate Z, Katarova Z and Szabo G (2010) GABA(A) and GABA(B) receptors of distinct properties affect oppositely the proliferation of mouse embryonic stem cells through synergistic elevation of intracellular Ca(2+). FASEB J 24, 1218-1228 https://doi.org/10.1096/fj.09-143586
- Teng L, Tang YB, Sun F et al (2013) Non-neuronal release of gamma-aminobutyric Acid by embryonic pluripotent stem cells. Stem Cells Dev 22, 2944-2953 https://doi.org/10.1089/scd.2013.0243
- Bachelerie F, Ben-Baruch A, Burkhardt AM et al (2014) International Union of Basic and Clinical Pharmacology. [corrected]. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors. Pharmacol Rev 66, 1-79 https://doi.org/10.1124/pr.113.007724
- Southgate TD, McGinn OJ, Castro FV et al (2010) CXCR4 mediated chemotaxis is regulated by 5T4 oncofetal glycoprotein in mouse embryonic cells. PLoS One 5, e9982 https://doi.org/10.1371/journal.pone.0009982
- Carbajal KS, Schaumburg C, Strieter R, Kane J and Lane TE (2010) Migration of engrafted neural stem cells is mediated by CXCL12 signaling through CXCR4 in a viral model of multiple sclerosis. Proc Natl Acad Sci U S A 107, 11068-11073 https://doi.org/10.1073/pnas.1006375107
- Williams JL, Patel JR, Daniels BP and Klein RS (2014) Targeting CXCR7/ACKR3 as a therapeutic strategy to promote remyelination in the adult central nervous system. J Exp Med 211, 791-799 https://doi.org/10.1084/jem.20131224
- Piomelli D (2003) The molecular logic of endocannabinoid signalling. Nat Rev Neurosci 4, 873-884 https://doi.org/10.1038/nrn1247
- Brown AJ (2007) Novel cannabinoid receptors. Br J Pharmacol 152, 567-575 https://doi.org/10.1038/sj.bjp.0707481
- Jiang S, Fu Y, Williams J et al (2007) Expression and function of cannabinoid receptors CB1 and CB2 and their cognate cannabinoid ligands in murine embryonic stem cells. PLoS One 2, e641 https://doi.org/10.1371/journal.pone.0000641
- Rossi F, Bernardo ME, Bellini G et al (2013) The cannabinoid receptor type 2 as mediator of mesenchymal stromal cell immunosuppressive properties. PLoS One 8, e80022 https://doi.org/10.1371/journal.pone.0080022
- Galve-Roperh I, Chiurchiu V, Diaz-Alonso J, Bari M, Guzman M and Maccarrone M (2013) Cannabinoid receptor signaling in progenitor/stem cell proliferation and differentiation. Prog Lipid Res 52, 633-650 https://doi.org/10.1016/j.plipres.2013.05.004
- Gowran A, McKayed K and Campbell VA (2013) The cannabinoid receptor type 1 is essential for mesenchymal stem cell survival and differentiation: implications for bone health. Stem Cells Int 2013, 796715 https://doi.org/10.1155/2013/796715
- McIntyre TM, Pontsler AV, Silva AR et al (2003) Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARgamma agonist. Proc Natl Acad Sci U S A 100, 131-136 https://doi.org/10.1073/pnas.0135855100
- Rodgers A, Mormeneo D, Long JS, Delgado A, Pyne NJ and Pyne S (2009) Sphingosine 1-phosphate regulation of extracellular signal-regulated kinase-1/2 in embryonic stem cells. Stem Cells Dev 18, 1319-1330 https://doi.org/10.1089/scd.2009.0023
- Schuck S, Soloaga A, Schratt G, Arthur JS and Nordheim A (2003) The kinase MSK1 is required for induction of c-fos by lysophosphatidic acid in mouse embryonic stem cells. BMC Mol Biol 4, 6 https://doi.org/10.1186/1471-2199-4-6
- Pebay A, Wong RC, Pitson SM et al (2005) Essential roles of sphingosine-1-phosphate and platelet-derived growth factor in the maintenance of human embryonic stem cells. Stem Cells 23, 1541-1548 https://doi.org/10.1634/stemcells.2004-0338
- Whetton AD, Lu Y, Pierce A, Carney L and Spooncer E (2003) Lysophospholipids synergistically promote primitive hematopoietic cell chemotaxis via a mechanism involving Vav 1. Blood 102, 2798-2802 https://doi.org/10.1182/blood-2002-12-3635
- Jaganathan BG, Ruester B, Dressel L et al (2007) Rho inhibition induces migration of mesenchymal stromal cells. Stem Cells 25, 1966-1974 https://doi.org/10.1634/stemcells.2007-0167
- Donati C, Cencetti F, Nincheri P et al (2007) Sphingosine 1-phosphate mediates proliferation and survival of mesoangioblasts. Stem Cells 25, 1713-1719 https://doi.org/10.1634/stemcells.2006-0725
- Song M, Paul S, Lim H, Dayem AA and Cho SG (2012) Induced pluripotent stem cell research: a revolutionary approach to face the challenges in drug screening. Arch Pharm Res 35, 245-260 https://doi.org/10.1007/s12272-012-0205-9
- Xu XX, Zhang LH and Xie X (2014) Somatostatin receptor type 2 contributes to the self-renewal of murine embryonic stem cells. Acta Pharmacol Sin 35, 1023-1030 https://doi.org/10.1038/aps.2014.51
- Schioth HB, Nordstrom KJ and Fredriksson R (2010) The adhesion GPCRs; gene repertoire, phylogeny and evolution. Adv Exp Med Biol 706, 1-13 https://doi.org/10.1007/978-1-4419-7913-1_1
- Yona S, Lin HH, Siu WO, Gordon S and Stacey M (2008) Adhesion-GPCRs: emerging roles for novel receptors. Trends Biochem Sci 33, 491-500 https://doi.org/10.1016/j.tibs.2008.07.005
- Bai Y, Du L, Shen L, Zhang Y and Zhang L (2009) GPR56 is highly expressed in neural stem cells but downregulated during differentiation. Neuroreport 20, 918-922 https://doi.org/10.1097/WNR.0b013e32832c92d7
- Formstone CJ and Little PF (2001) The flamingo-related mouse Celsr family (Celsr1-3) genes exhibit distinct patterns of expression during embryonic development. Mech Dev 109, 91-94 https://doi.org/10.1016/S0925-4773(01)00515-9
- Seandel M, Falciatori I, Shmelkov SV, Kim J, James D and Rafii S (2008) Niche players: spermatogonial progenitors marked by GPR125. Cell Cycle 7, 135-140 https://doi.org/10.4161/cc.7.2.5248
- Foord SM, Bonner TI, Neubig RR et al (2005) International Union of Pharmacology. XLVI. G protein-coupled receptor list. Pharmacol Rev 57, 279-288 https://doi.org/10.1124/pr.57.2.5
- Wang HY, Liu T and Malbon CC (2006) Structure-function analysis of Frizzleds. Cell Signal 18, 934-941 https://doi.org/10.1016/j.cellsig.2005.12.008
- Nusse R (2008) Wnt signaling and stem cell control. Cell Res 18, 523-527 https://doi.org/10.1038/cr.2008.47
- Cai L, Ye Z, Zhou BY, Mali P, Zhou C and Cheng L (2007) Promoting human embryonic stem cell renewal or differentiation by modulating Wnt signal and culture conditions. Cell Res 17, 62-72 https://doi.org/10.1038/sj.cr.7310138
- Walsh J and Andrews PW (2003) Expression of Wnt and Notch pathway genes in a pluripotent human embryonal carcinoma cell line and embryonic stem cell. APMIS 111, 197-210; discussion 210-191 https://doi.org/10.1034/j.1600-0463.2003.1110124.x
- Ding VM, Ling L, Natarajan S, Yap MG, Cool SM and Choo AB (2010) FGF-2 modulates Wnt signaling in undifferentiated hESC and iPS cells through activated PI3-K/GSK3beta signaling. J Cell Physiol 225, 417-428 https://doi.org/10.1002/jcp.22214
- Melchior K, Weiss J, Zaehres H et al (2008) The WNT receptor FZD7 contributes to self-renewal signaling of human embryonic stem cells. Biol Chem 389, 897-903 https://doi.org/10.1515/BC.2008.108
- Tam WL, Lim CY, Han J et al (2008) T-cell factor 3 regulates embryonic stem cell pluripotency and self-renewal by the transcriptional control of multiple lineage pathways. Stem Cells 26, 2019-2031 https://doi.org/10.1634/stemcells.2007-1115
- Kelly KF, Ng DY, Jayakumaran G, Wood GA, Koide H and Doble BW (2011) beta-catenin enhances Oct-4 activity and reinforces pluripotency through a TCF-independent mechanism. Cell Stem Cell 8, 214-227 https://doi.org/10.1016/j.stem.2010.12.010
- Lyashenko N, Winter M, Migliorini D, Biechele T, Moon RT and Hartmann C (2011) Differential requirement for the dual functions of beta-catenin in embryonic stem cell self-renewal and germ layer formation. Nat Cell Biol 13, 753-761 https://doi.org/10.1038/ncb2260
- Yi F, Pereira L, Hoffman JA et al (2011) Opposing effects of Tcf3 and Tcf1 control Wnt stimulation of embryonic stem cell self-renewal. Nat Cell Biol 13, 762-770 https://doi.org/10.1038/ncb2283
- Miki T, Yasuda SY and Kahn M (2011) Wnt/beta-catenin signaling in embryonic stem cell self-renewal and somatic cell reprogramming. Stem Cell Rev 7, 836-846 https://doi.org/10.1007/s12015-011-9275-1
- Afroze S, Meng F, Jensen K et al (2013) The physiological roles of secretin and its receptor. Ann Transl Med 1, 29
- Dickson L and Finlayson K (2009) VPAC and PAC receptors: From ligands to function. Pharmacol Ther 121, 294-316 https://doi.org/10.1016/j.pharmthera.2008.11.006
- Lee CH, Kim JH, Lee HJ et al (2011) The generation of iPS cells using non-viral magnetic nanoparticle based transfection. Biomaterials 32, 6683-6691 https://doi.org/10.1016/j.biomaterials.2011.05.070
- Yang W, Wei W, Shi C et al (2009) Pluripotin combined with leukemia inhibitory factor greatly promotes the derivation of embryonic stem cell lines from refractory strains. Stem Cells 27, 383-389 https://doi.org/10.1634/stemcells.2008-0974
- Maherali N and Hochedlinger K (2008) Guidelines and techniques for the generation of induced pluripotent stem cells. Cell Stem Cell 3, 595-605 https://doi.org/10.1016/j.stem.2008.11.008
- Teng HF, Kuo YL, Loo MR et al (2010) Valproic acid enhances Oct4 promoter activity in myogenic cells. J Cell Biochem 110, 995-1004 https://doi.org/10.1002/jcb.22613
- Spinsanti P, De Vita T, Di Castro S et al (2006) Endogenously activated mGlu5 metabotropic glutamate receptors sustain the increase in c-Myc expression induced by leukaemia inhibitory factor in cultured mouse embryonic stem cells. J Neurochem 99, 299-307 https://doi.org/10.1111/j.1471-4159.2006.04038.x
- Sarichelou I, Cappuccio I, Ferranti F et al (2008) Metabotropic glutamate receptors regulate differentiation of embryonic stem cells into GABAergic neurons. Cell Death Differ 15, 700-707 https://doi.org/10.1038/sj.cdd.4402298
- Todorova MG, Fuentes E, Soria B, Nadal A and Quesada I (2009) Lysophosphatidic acid induces Ca2+ mobilization and c-Myc expression in mouse embryonic stem cells via the phospholipase C pathway. Cell Signal 21, 523-528 https://doi.org/10.1016/j.cellsig.2008.12.005
- Seandel M, James D, Shmelkov SV et al (2007) Generation of functional multipotent adult stem cells from GPR125+ germline progenitors. Nature 449, 346-350 https://doi.org/10.1038/nature06129
- Carson-Walter EB, Watkins DN, Nanda A, Vogelstein B, Kinzler KW and St Croix B (2001) Cell surface tumor endothelial markers are conserved in mice and humans. Cancer Res 61, 6649-6655
- Marson A, Foreman R, Chevalier B et al (2008) Wnt signaling promotes reprogramming of somatic cells to pluripotency. Cell Stem Cell 3, 132-135 https://doi.org/10.1016/j.stem.2008.06.019
- Zhang P, Chang WH, Fong B et al (2014) Regulation of induced pluripotent stem (iPS) cell induction by Wnt/beta-catenin signaling. J Biol Chem 289, 9221-9232 https://doi.org/10.1074/jbc.M113.542845
- Bonnet D and Dick JE (1997) Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 3, 730-737 https://doi.org/10.1038/nm0797-730
- Rodriguez-Pinilla SM, Sarrio D, Moreno-Bueno G et al (2007) Sox2: a possible driver of the basal-like phenotype in sporadic breast cancer. Mod Pathol 20, 474-481 https://doi.org/10.1038/modpathol.3800760
- Prevarskaya N, Skryma R and Shuba Y (2011) Calcium in tumour metastasis: new roles for known actors. Nat Rev Cancer 11, 609-618 https://doi.org/10.1038/nrc3105
- Dean M (2006) Cancer stem cells: redefining the paradigm of cancer treatment strategies. Mol Interv 6, 140-148 https://doi.org/10.1124/mi.6.3.5
- Hernandez L, Magalhaes MA, Coniglio SJ, Condeelis JS and Segall JE (2011) Opposing roles of CXCR4 and CXCR7 in breast cancer metastasis. Breast Cancer Res 13, R128 https://doi.org/10.1186/bcr3074
- Wu X, Lee VC, Chevalier E and Hwang ST (2009) Chemokine receptors as targets for cancer therapy. Curr Pharm Des 15, 742-757 https://doi.org/10.2174/138161209787582165
- Lazennec G and Richmond A (2010) Chemokines and chemokine receptors: new insights into cancer-related inflammation. Trends Mol Med 16, 133-144 https://doi.org/10.1016/j.molmed.2010.01.003
- Ablett MP, O'Brien CS, Sims AH, Farnie G and Clarke RB (2014) A differential role for CXCR4 in the regulation of normal versus malignant breast stem cell activity. Oncotarget 5, 599-612 https://doi.org/10.18632/oncotarget.1169
- Burdon T, Smith A and Savatier P (2002) Signalling, cell cycle and pluripotency in embryonic stem cells. Trends Cell Biol 12, 432-438 https://doi.org/10.1016/S0962-8924(02)02352-8
- Levoye A, Balabanian K, Baleux F, Bachelerie F and Lagane B (2009) CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling. Blood 113, 6085-6093 https://doi.org/10.1182/blood-2008-12-196618
- Sarfaraz S, Adhami VM, Syed DN, Afaq F and Mukhtar H (2008) Cannabinoids for cancer treatment: progress and promise. Cancer Res 68, 339-342 https://doi.org/10.1158/0008-5472.CAN-07-2785
- Aguado T, Carracedo A, Julien B et al (2007) Cannabinoids induce glioma stem-like cell differentiation and inhibit gliomagenesis. J Biol Chem 282, 6854-6862 https://doi.org/10.1074/jbc.M608900200
- Rogelsperger O, Ekmekcioglu C, Jager W et al (2009) Coexpression of the melatonin receptor 1 and nestin in human breast cancer specimens. J Pineal Res 46, 422-432 https://doi.org/10.1111/j.1600-079X.2009.00679.x
- Tan DX, Manchester LC, Terron MP, Flores LJ and Reiter RJ (2007) One molecule, many derivatives: a never-ending interaction of melatonin with reactive oxygen and nitrogen species? J Pineal Res 42, 28-42 https://doi.org/10.1111/j.1600-079X.2006.00407.x
- Ledur PF, Villodre ES, Paulus R, Cruz LA, Flores DG and Lenz G (2012) Extracellular ATP reduces tumor sphere growth and cancer stem cell population in glioblastoma cells. Purinergic Signal 8, 39-48 https://doi.org/10.1007/s11302-011-9252-9
- Lonardo E, Hermann PC and Heeschen C (2010) Pancreatic cancer stem cells - update and future perspectives. Mol Oncol 4, 431-442 https://doi.org/10.1016/j.molonc.2010.06.002
- MacDonald BT, Tamai K and He X (2009) Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell 17, 9-26 https://doi.org/10.1016/j.devcel.2009.06.016
- Moriconi A, Cesta MC, Cervellera MN et al (2007) Design of noncompetitive interleukin-8 inhibitors acting on CXCR1 and CXCR2. J Med Chem 50, 3984-4002 https://doi.org/10.1021/jm061469t
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