DOI QR코드

DOI QR Code

Diphyllobothrium nihonkaiense Infections in a Family

  • Go, Young Bin (Department of Pediatrics, Myongji Hospital) ;
  • Lee, Eun Hye (Department of Pediatrics, Myongji Hospital) ;
  • Cho, Jaeeun (Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine) ;
  • Choi, Seoyun (Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine) ;
  • Chai, Jong-Yil (Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine)
  • Received : 2014.07.16
  • Accepted : 2015.01.02
  • Published : 2015.02.28

Abstract

Diphyllobothrium latum and Diphyllobothrium nihonkaiense are morphologically similar to each other, and only genetic method can differentiate clearly between the 2 species. A strobila of diphyllobothriid tapeworm discharged from a 7-year-old boy was analyzed to identify the species by mitochondrial cytochrome c oxidase subunit 1 (cox1) gene sequencing. He and his family (total 4 persons) ate slices of 3 kinds of raw fish 16 days before visiting our outpatient clinic. All family members complained of abdominal pain and watery diarrhea. They all expelled tapeworm strobilae in their stools. They were treated with a single oral dose of praziquantel and then complained of no more symptoms. The cox1 gene sequencing of the strobila from the boy revealed 99.9% (687/688 bp) similarity with D. nihonkaiense and only 93.2% (641/688 bp) similarity with D. latum. Thus, we assigned this tapeworm as D. nihonkaiense. This is the first report of D. nihonkaiense infection in a family in Korea, and this report includes the 8th pediatric case in Korea. The current report is meaningful because D. nihonkaiense infection within a family is rare.

Keywords

References

  1. Chai JY, Murrell KD, Lymbery AJ. Fish-borne parasitic zoonoses: status and issues. Int J Parasitol 2005; 35: 1233-1254. https://doi.org/10.1016/j.ijpara.2005.07.013
  2. Lee KW, Suhk HC, Pai KS, Shin HJ, Jung SY, Han ET, Chai JY. Diphyllobothrium latum infection after eating domestic salmon flesh. Korean J Parasitol 2001; 39: 319-321. https://doi.org/10.3347/kjp.2001.39.4.319
  3. Scholz T, Garcia HH, Kuchta R, Wicht B. Update on the human broad tapeworm (genus Diphyllobothrium), including clinical relevance. Clin Microbiol Rev 2009; 22: 146-160. https://doi.org/10.1128/CMR.00033-08
  4. Lee EB, Song JH, Park NS, Kang BK, Lee HS, Han YJ, Kim HJ, Shin EH, Chai JY. A case of Diphyllobothrium latum infection with a brief review of diphyllobothriasis in the Republic of Korea. Korean J Parasitol 2007; 45: 219-223. https://doi.org/10.3347/kjp.2007.45.3.219
  5. Kojima R, Ko T. Researches on intestinal parasites of Koreans in South Keisho-Do, especially on the distribution of liver flukes. J Chosen Med Ass 1919; 26: 42-86.
  6. Cho SY, Seo BS, Ahn JH. One case report of Diphyllobothrium latum infection in Korea. Seoul J Med 1971; 12: 157-163.
  7. Jeong KH, Lee JS, Rim HJ. A case report of Diphyllobothrium latum infection. J Soonchunhyang Univ 1980; 3: 155-160.
  8. Jeon HK, Kim KH, Huh S, Chai JY, Min DY, Rim HJ, Eom KS. Morphologic and genetic identification of Diphyllobothrium nihonkaiense in Korea. Korean J Parasitol 2009; 47: 369-375. https://doi.org/10.3347/kjp.2009.47.4.369
  9. Wicht B, Yanagida T, Scholz T, Ito A, Jimenez JA, Brabec J. Multiplex PCR for differential identification of broad tapeworms (Cestoda: Diphyllobothrium) infecting humans, J Clin Microbiol 2010; 48: 3111-3116. https://doi.org/10.1128/JCM.00445-10
  10. Yamane Y, Kamo H, Bylund G, Wikgren BJP. Diphyllobothrium nihonkaiense sp. nov. (Cestoda: Diphyllobothriidae)-revised identification of Japanese broad tapeworm. Shimane J Med Sci 1986; 10: 29-48.
  11. Rim HJ, Lee JS, Joo KH, Kim KH, Lee JH. Occurrence of human infection with Diphyllobothrium nihonkaiense Yamane et al.,1986 in Korea. Korean J Parasitol 1990; 28: 292.
  12. Choi HJ, Lee J, Yang HJ. Four human cases of Diphyllobothrium latum infection. Korean J Parasitol 2012; 50: 143-146. https://doi.org/10.3347/kjp.2012.50.2.143
  13. Park SH, Eom KS, Park MS, Kwon OK, Kim HS, Yoon JH. A case of Diphyllobothrium nihonkaiense infection as confirmed by mitochondrial COX1 gene sequence analysis. Korean J Parasitol 2013; 51: 471-473. https://doi.org/10.3347/kjp.2013.51.4.471
  14. Song SM, Yang HW, Jung MK, Heo J, Cho CM, Goo YK, Hong Y, Chung DI. Two human cases of Diphyllobothrium nihonkaiense infection in Korea. Korean J Parasitol 2014; 52: 197-199. https://doi.org/10.3347/kjp.2014.52.2.197
  15. Kim HJ, Eom KS, Seo M. Three cases of Diphyllobothrium nihonkaiense infection in Korea. Korea J Parasitol 2014; 52: 673-676. https://doi.org/10.3347/kjp.2014.52.6.673
  16. Suzuki J, Murata R, Yanagawa Y, Araki J. Identification of Diphyllobothrium nihonkaiense by PCR-based approach. Clin Parasitol (Japan) 2006; 17: 22-24.
  17. Yera H, Estran C, Delaunay P, Gari-Toussaint M, Dupouy-Camet J, Marty P. Putative Diphyllobothrium nihonkaiense acquired from a Pacific salmon (Oncorhynchus keta) eaten in France: genomic identification and case report. Parasitol Int 2006; 55: 45-49. https://doi.org/10.1016/j.parint.2005.09.004
  18. Wicht B, Scholz T, Kuchta R. First record of human infection with the tapeworm Diphyllobothium nihonkaiense in North America. Am J Trop Med Hyg 2008; 78: 235-238.
  19. Yamasaki H, Kuramochi T. A case of Diphyllobothrium nihonkaiense infection possibly linked to salmon consumption in New Zealand. Parasitol Res 2009; 105: 583-586. https://doi.org/10.1007/s00436-009-1468-z
  20. de Marval F, Gottstein B, Weber M, Wicht B. Imported diphyllobothriasis in Switzerland: molecular methods to define a clinical case of Diphyllobothrium infection as Diphyllobothrium dendriticum, August 2010. Euro Surveill 2013; 18: pii=20355.
  21. Wicht B, de Marval F, Peduzzi R. Diphyllobothrium nihonkaiense (Yamane et al.,1986) in Switzerland: first molecular evidence and case reports. Parasitol Int 2007; 56: 195-199. https://doi.org/10.1016/j.parint.2007.02.002
  22. Shimizu H, Kawakatsu H, Shimizu T, Yamada M, Teqoshi T, Uchikawa R, Arizono N. Diphyllobothriasis nihonkaiense; possibly acquired in Switzerland from imported Pacific salmon. Intern Med 2008; 47: 1359-1362. https://doi.org/10.2169/internalmedicine.47.1026
  23. Paugam A, Yera H, Poirier P, Lebuisson A, Dupouy-Camet J. Diphyllobothrium nihonkaiense infection: a new risk in relation with the consumption of salmon. Presse Med 2009; 38: 675-677. https://doi.org/10.1016/j.lpm.2008.06.017
  24. Cabello FC. Salmon aquaculture and transmission of the fish tapeworm. Emerg Infect Dis 2007; 13: 169-171. https://doi.org/10.3201/eid1301.060875

Cited by

  1. Epidemiology of Diphyllobothrium nihonkaiense Diphyllobothriasis, Japan, 2001–2016 vol.24, pp.8, 2018, https://doi.org/10.3201/eid2408.171454