Journal of Yeungnam Medical Science

Yeungnam University College of Medicine, Yeungnam University Institute Medical Science (영남대 의대 학술지 편집위원회)
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Cellular origin of liver cancer stem cells

간암 줄기세포의 기원

  • Eun, Jong Ryeol (Department of Internal Medicine, Myongji Hospital, Seonam University College of Medicine)
  • 은종렬 (서남대학교 의과대학 명지병원 내과학교실)
  • Received : 2015.05.19
  • Accepted : 2015.06.05
  • Published : 2015.06.30
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Abstract

Over several decades, a hierarchical cancer stem cell (CSC) model has been established in development of solid cancers, including hepatocellular carcinoma(HCC). In terms of this concept, HCCs originate from liver CSCs. Clinically HCCs show a wide range of manifestations from slow growth to very aggressive metastasis. One of the reasons may be that liver CSCs originate from different cells. This review describes the basic concept of CSCs and the cellular origin of liver CSCs.

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