Journal of Biomedical Engineering Research (대한의용생체공학회:의공학회지)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
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Development of a Multi-nozzle Bioprinting System for 3D Scaffold Fabrication

3차원 지지체 제작을 위한 다중 분사체 노즐 바이오프린팅 시스템 개발

  • Park, Sanghoon (Asan Institute for Life Sciences, Asan Medical Center) ;
  • Kim, Seongjun (Asan Institute for Life Sciences, Asan Medical Center) ;
  • Song, Seung-Joon (Daelim University College, Dept. of Convergence Biomedical Engineering) ;
  • Choi, Jaesoon (Asan Institute for Life Sciences, Asan Medical Center)
  • 박상훈 (서울아산병원 의공학연구소) ;
  • 김성준 (서울아산병원 의공학연구소) ;
  • 송승준 (대림대학교 의공융합과) ;
  • 최재순 (서울아산병원 의공학연구소)
  • Received : 2015.10.05
  • Accepted : 2015.12.22
  • Published : 2015.12.31
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Abstract

The aim of this study was to develop a multi-nozzle based bioprinting system for fabrication of three-dimensional (3D) biological structure. In this study, a thermoplastic biomaterial that has relatively high mechanical stability, polycaprolactone (PCL) was used to make the 3D structure. A multi-nozzle bioprinting system was designed to dispense thermoplastic biomaterial and hydrogel simultaneously. The system that consists of 3-axes of x-y-z motion control stage and a compartment for injection syringe control mounted on the stage has been developed. Also, it has 1-axis actuator for position change of nozzle. The controllability of the printed line width with PCL was tested as a representative performance index.

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References

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