Journal of Sensor Science and Technology (센서학회지)

The Korean Sensors Society (한국센서학회)
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Implantable Nerve Cuff Electrode with Conductive Polymer for Improving Recording Signal Quality at Peripheral Nerve

말초 신경 신호 기록의 효율성 개선을 위한 전도성 폴리머가 적용된 생체삽입형 커프형 신경전극

  • Park, Sung Jin (Center for BioMicroSystems, Korea Institute of Science and Technology) ;
  • Lee, Yi Jae (Center for BioMicroSystems, Korea Institute of Science and Technology) ;
  • Yun, Kwang-Seok (Department of Electronic Engineering, Sogang University) ;
  • Kang, Ji Yoon (Center for BioMicroSystems, Korea Institute of Science and Technology) ;
  • Lee, Soo Hyun (Center for BioMicroSystems, Korea Institute of Science and Technology)
  • 박성진 (한국과학기술연구원 바이오마이크로시스템연구단) ;
  • 이이재 (한국과학기술연구원 바이오마이크로시스템연구단) ;
  • 윤광석 (서강대학교 전자공학과) ;
  • 강지윤 (한국과학기술연구원 바이오마이크로시스템연구단) ;
  • 이수현 (한국과학기술연구원 바이오마이크로시스템연구단)
  • Received : 2014.10.30
  • Accepted : 2014.11.28
  • Published : 2015.01.31
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Abstract

This study demonstrates a polyimide nerve cuff electrode with a conductive polymer for improving recording signal quality at peripheral nerve. The nerve cuff electrodes with platinum (Pt), iridium oxide (IrOx), and poly(3,4-ethylenedioxythiophene): p-toluene sulfonate (PEDOT:pTS) were fabricated and investigated their electrical characteristics for improving recorded nerve signal quality. The fabricated nerve cuff electrodes with Pt, IrOx, and PEDOT:pTS were characterized their impedance and CDC by using electrochemical impedance spectroscopy (EIS) and cyclic voltammetry. The impedance of PEDOT:pTS measured at 1 kHz was $257{\Omega}$, which was extremely lower than the value of the nerve cuff electrodes with IrOx ($15897{\Omega}$) and Pt ($952{\Omega}$), respectively. Furthermore, the charge delivery capacity (CDC) of the nerve cuff electrode with PEDOT:pTS was dramatically increased to 62 times than the nerve cuff electrode with IrOx. In ex-vivo test using extracted sciatic nerve of spaque-dawley rat (SD rat), the PEDOT:pTS group exhibited higher signal-to-interference ratio than IrOx group. These results indicated that the nerve cuff electrode with PEDOT:pTS is promising for effective implantable nerve signal recording.

Keywords

References

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