The Journal of Korean Medicine (대한한의학회지)

The Society of Korean Medicine (대한한의학회)
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A Study about Quality Control of Herb Medicine Extract Granules - About DanggwiSayeuggaosuyusaenggangtang(DSGOST)

  • Sung, Hyun Kyung (Dept. of Korean Pediatrics, College of Korean Medicine, Semyung University) ;
  • Go, Ho Yeon (Dept. of Korean Internal Medicine, College of Korean Medicine, Semyung University) ;
  • Sun, Seung Ho (Dept. of Korean Internal Medicine, College of Korean Medicine, Sangji University) ;
  • Ko, Youme (Dept. of Preventive Medicine, College of Korean Medicine, Kyunghee University) ;
  • Ko, Seong Gyu (Dept. of Preventive Medicine, College of Korean Medicine, Kyunghee University) ;
  • Song, Yun Kyung (Dept. of Korean Rehabilitation Medicine, College of Korean Medicine, Gachon University) ;
  • Kim, Tae Hoon (Dept. of Clinical Research of Korean Medicine, College of Korean Medicine, Kyunghee University) ;
  • Sim, Sung Yong (Dept. of Korean Opthalmology & Otolaryngology & Dermatology, College of Korean Medicine, Gachon University) ;
  • Lee, Hye Lim (Dept. of Korean Pediatrics, College of Korean Medicine, Gachon University) ;
  • Jung, Ki Yong (Dept. of Korean Internal Medicine, College of Korean Medicine, Gachon University) ;
  • Park, Chong Hyeong (Dept. of Korean Internal Medicine, College of Korean Medicine, Gachon University) ;
  • Choi, You Kyung (Dept. of Korean Internal Medicine, College of Korean Medicine, Gachon University) ;
  • Lee, Min Hye (Dept. of Korean Internal Medicine, College of Korean Medicine, Gachon University) ;
  • Lim, Eun Mee (Dept. of Korean Gynecology, College of Korean Medicine, Gachon University) ;
  • Jeon, Chan Yong (Dept. of Korean Internal Medicine, College of Korean Medicine, Gachon University)
  • Received : 2015.12.15
  • Accepted : 2015.12.29
  • Published : 2015.12.30
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Abstract

Objectives: This study investigated quality among three herb medicine extract granules(DSGOST) which were made from different companies to check quality control of herb medicine extract granules. Methods: we selected three DSGOST extract granules which were made from different companies. And we experimented extract granules by method from K.P(Korean Pharmacopoeia), K.H.P(Korean Herbal Pharmacopoeia) of KFDA. Results: In qualitative analysis of DSGOST, we indentified Akebiae Caulis (木通), Asari Herba Cum Radix (細辛), Evodiae Fructus (吳茱萸) in three different DSGOST extract granules. In quantitative analysis of DSGOST, Medication A,B,C contained similar content of Paeoniflorin & Glycyrrhizic acid. However Medication B contains especially lowest value of Cinnamic acid & total Decursin. Conclusions: Herb medicine extract granules have different contents of ingredients although those were made by same prescription. And these differences may influence medicinal effect to patients. So we need to make system of quality control with various research of quantitative & qualitative analysis about herb medicine extract granules.

Keywords

References

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