Journal of Cardiovascular Imaging

  • 제23권3호
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  • Pages.150-157
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  • 2015
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  • 2586-7210(pISSN)
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  • 2586-7296(eISSN)
한국심초음파학회 (Korean Society of Echocardiography)
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IMPAIRED DIASTOLIC RECOVERY AFTER ACUTE MYOCARDIAL INFARCTION AS A PREDICTOR OF ADVERSE EVENTS

  • Yoon, Hyun Ju (Department of Cardiovascular Medicine, Chonnam National University Hospital) ;
  • Kim, Kye Hun (Department of Cardiovascular Medicine, Chonnam National University Hospital) ;
  • Kim, Jong Yoon (Department of Cardiovascular Medicine, Chonnam National University Hospital) ;
  • Cho, Jae Young (Department of Cardiovascular Medicine, Chonnam National University Hospital) ;
  • Yoon, Nam Sik (Department of Cardiovascular Medicine, Chonnam National University Hospital) ;
  • Park, Hyung Wook (Department of Cardiovascular Medicine, Chonnam National University Hospital) ;
  • Hong, Young Joon (Department of Cardiovascular Medicine, Chonnam National University Hospital) ;
  • Kim, Ju Han (Department of Cardiovascular Medicine, Chonnam National University Hospital) ;
  • Ahn, Youngkeun (Department of Cardiovascular Medicine, Chonnam National University Hospital) ;
  • Jeong, Myung Ho (Department of Cardiovascular Medicine, Chonnam National University Hospital) ;
  • Cho, Jeong Gwan (Department of Cardiovascular Medicine, Chonnam National University Hospital) ;
  • Park, Jong Chun (Department of Cardiovascular Medicine, Chonnam National University Hospital)
  • 투고 : 2015.05.22
  • 심사 : 2015.09.02
  • 발행 : 2015.09.27
⟨ 이전 논문 다음 논문 ⟩

초록

BACKGROUND: To investigate the impact of left ventricular (LV) diastolic functional recovery on major adverse cardiac events (MACE) 6 months after acute myocardial infarction (AMI) in patients with preserved LV systolic function. METHODS: A total 463 patients with preserved LV systolic function at 6 months after an AMI were divided into two groups based on the extent of diastolic recovery assessed by echocardiography: group I (n = 241) showed improving diastolic function and group II (n = 222) did not. MACE included death, recurrent myocardial infarction, and rehospitalization due to heart failure, and these events were compared with the patients' characteristics at baseline. RESULTS: Compared with group I, the patients in group II were older and had a higher prevalence of hypertension and diabetes. Blood levels of hemoglobin and triglyceride were lower in group II, whereas the levels of N-terminal pro-B-type natriuretic peptide (NT-proBNP) and of high-sensitivity C-reactive protein were higher in this group than in group I. MACE were significantly more frequent in group II than in group I. Age, elevated NT-proBNP, and impaired diastolic recovery were significant independent predictors of MACE. CONCLUSION: Despite improvement in LV systolic function, LV diastolic function had not improved in 222 patients (47.9%) by the 6-month follow-up after the index AMI, and impaired diastolic functional recovery was found to be an independent predictor of MACE. Evaluation of diastolic function would be a useful way to stratify risk in patients discharged after an index AMI.

키워드

과제정보

연구 과제 주관 기관 : Korean Society of Echocardiography

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