Advances in materials Research

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Biophysical properties of PPF/HA nanocomposites reinforced with natural bone powder

  • Kamel, Nagwa A. (Microwave Physics and Dielectrics Department, National Research Centre) ;
  • Mansour, Samia H. (Polymers and Pigments Department, National Research Centre) ;
  • Abd-El-Messieh, Salwa L. (Microwave Physics and Dielectrics Department, National Research Centre) ;
  • Khalil, Wafaa A. (Biophysics Department, Faculty of Science, Cairo University) ;
  • Abd-El Nour, Kamal N. (Microwave Physics and Dielectrics Department, National Research Centre)
  • Received : 2015.03.19
  • Accepted : 2015.11.16
  • Published : 2015.09.25
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Abstract

Biodegredable and injectable nanocomposites based on polypropylene fumarate (PPF) as unsaturated polyester were prepared. The investigated polyester was crosslinked with three different monomers namely N-vinyl pyrrolidone (NVP), methyl methacrylate (MMA) and a mixture of NVP and MMA (1:1 weight ratio) and was filled with 45 wt% of hydroxyapatite (HA) incorporated with different concentrations of chemically treated natural bone powder (NBP) (5, 10 and 15 wt%) in order to be used in treatment of orthopedics bone diseases and fractures. The nanocomposites immersed in the simulated body fluid (SBF) for 30 days, after the period of immersion in-vitro bioactivity of the nanocomposites was studied through Fourier transform infrared (FTIR), scanning electron microscope (SEM), energy dispersive X-ray (EDX) in addition to dielectric measurements. The degradation time of immersed samples and the change in the pH of the SBF were studied during the period of immersion.

Keywords

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