Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
권호 표지
DOI QR코드

DOI QR Code

Sporothrix schenckii Infection in a Dog with Concurrent Hyperadrenocorticism and Diabetes Mellitus

부신겉질기능항진증과 당뇨 병발 개에서 Sporothrix schenckii 감염 증례

  • Song, Jaeyong (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Kangwon National University) ;
  • Lee, Bareun (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Kangwon National University) ;
  • Kim, Hyun-Min (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Kangwon National University) ;
  • Kang, Jooyeon (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Kangwon National University) ;
  • Cho, Hyunkee (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Kangwon National University) ;
  • Choi, Ul-Soo (Department of Veterinary Clinical Pathology, College of Veterinary Medicine, Chonbuk National University) ;
  • Hwang, Cheol-Yong (Department of Dermatology, College of Veterinary Medicine, Seoul National University) ;
  • Choi, Jung Hoon (Department of Anatomy, College of Veterinary Medicine, Kangwon National University) ;
  • Chung, Jin-Young (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Kangwon National University)
  • 송재용 (강원대학교 수의과대학 내과학) ;
  • 이바른 (강원대학교 수의과대학 내과학) ;
  • 김현민 (강원대학교 수의과대학 내과학) ;
  • 강주연 (강원대학교 수의과대학 내과학) ;
  • 조현기 (강원대학교 수의과대학 내과학) ;
  • 최을수 (전북대학교 수의과대학 임상병리학) ;
  • 황철용 (서울대학교 수의과대학 피부과학) ;
  • 최정훈 (강원대학교 수의과대학 해부학) ;
  • 정진영 (강원대학교 수의과대학 내과학)
  • Accepted : 2015.12.21
  • Published : 2015.12.31
Download PDF
⟨ Previous Next ⟩

Abstract

A 12-year-old spayed Pomeranian was presented with a purulent, erythematous mass. The dog also suffered from concurrent hyperadrenocorticism and diabetes mellitus. Sporothrix schenckii was isolated through the fungal culture of the mass. Surgical ablation of the mass was performed for the removal of continuous inflammation and fungal infection of deep origin. After histological examination of the mass, severe multifocal pyogranulomatous dermatitis and panniculitis were diagnosed. This is the first confirmed case of pyogranulomatous dermatitis and panniculitis due to Sporothrix schenckii infection in a dog with concurrent hyperadrenocorticism and diabetes mellitus. In addition this is the first case report of sporotrichosis in South Korea.

12살 중성화 암컷 Pomeranian이 화농성, 홍반성 피부 종괴를 주증으로 내원하였다. 본 환자는 기존에 당뇨와 부신겉질기능항진증을 진단받고 처치받고 있었다. 신체검사, 혈액검사, 영상학적 검사상 특별한 이상이 발견되지 않았고, 병변 부위의 곰팡이 배양 결과 Sporothrix schenckii가 동정되었다. Fluconazole을 7일간 처방하였으나 개선 양상이 보이지 않아, 지속적인 감염과 심부의 곰팡이 감염을 제거하기 위해 종괴의 외과적 절제를 실시하였다. 종괴의 조직학적 검사상, 심각한 다발성 농성육아종성 피부염과 지방층염을 진단하였다. 본 증례는 내분비 질환 병발 개에서 Sporothrix schenckii의 감염에 의한 다발성 농성육아종성 피부염과 지방층염의 첫번째 증례이다. 특히 동물에서 Sporothrix schenckii의 한국에서의 첫번째 보고이다.

Keywords

References

  1. Barros MB, de Almeida Paes R, Schubach AO. Sporothrix schenckii and Sporotrichosis. Clin Microbiol Rev 2011; 24: 633-654. https://doi.org/10.1128/CMR.00007-11
  2. Bonifaz A, Saul A, Paredes-Solis V, Fierro L, Rosales A, Palacios C, Araiza J. Sporotrichosis in childhood: clinical and therapeutic experience in 25 patients. Pediatr Dermatol 2007; 24: 369-372. https://doi.org/10.1111/j.1525-1470.2007.00452.x
  3. Casqueiro J, Casqueiro J, Alves C. Infections in patients with diabetes mellitus: A review of pathogenesis. Indian J Endocrinol Metab 2012; 16 Suppl 1: S27-36. https://doi.org/10.4103/2230-8210.94253
  4. Crothers SL, White SD, Ihrke PJ, Affolter VK. Sporotrichosis: a retrospective evaluation of 23 cases seen in northern California (1987-2007). Vet Dermatol 2009; 20: 249-259. https://doi.org/10.1111/j.1365-3164.2009.00763.x
  5. Gordon CB, Li DG, Stagg CA, Manson P, Udelsman R. Impaired wound healing in Cushing's syndrome: the role of heat shock proteins. Surgery 1994; 116: 1082-1087.
  6. Kauffman CA. Sporotrichosis. Clin Infect Dis 1999; 29: 231-236; quiz 237. https://doi.org/10.1086/520190
  7. Kim S, Rusk MH, James WD. Erysipeloid sporotrichosis in a woman with Cushing's disease. J Am Acad Dermatol 1999; 40: 272-274. https://doi.org/10.1016/S0190-9622(99)70205-7
  8. Larsson CE, Goncalves Mde A, Araujo VC, Dagli ML, Correa B, Fava Neto C. Feline sporotrichosis: clinical and zoonotic aspects. Rev Inst Med Trop Sao Paulo 1989; 31: 351-358. https://doi.org/10.1590/S0036-46651989000500010
  9. Miller WH, Griffin CE, Campbell KL, Muller GH, Scott DW. Muller & Kirk's small animal dermatology, 7th ed. St. Louis, Mo.: Elsevier. 2013: 514-525.
  10. Nelson RW, Couto CG. Small animal internal medicine, 5th ed. St. Louis, Mo.: Mosby/Elsevier. 2014: 841.
  11. Ramos-e-Silva M, Vasconcelos C, Carneiro S, Cestari T. Sporotrichosis. Clin Dermatol 2007; 25: 181-187. https://doi.org/10.1016/j.clindermatol.2006.05.006
  12. Ryan KJ, Ray CG, Sherris JC. Sherris medical microbiology: an introduction to infectious diseases, 4th ed. New York: McGraw-Hill. 2004: 654-656.
  13. Schubach TM, Schubach Ade O, Cuzzi-Maya T, Okamoto T, Reis RS, Monteiro PC, Gutierrez-Galhardo MC, Wanke B. Pathology of sporotrichosis in 10 cats in Rio de Janeiro. Vet Rec 2003; 152: 172-175. https://doi.org/10.1136/vr.152.6.172
  14. Schubach TM, Schubach A, Okamoto T, Barros MB, Figueiredo FB, Cuzzi T, Pereira SA, Dos Santos IB, Almeida Paes R, Paes Leme LR, Wanke B. Canine sporotrichosis in Rio de Janeiro, Brazil: clinical presentation, laboratory diagnosis and therapeutic response in 44 cases (1998-2003). Med Mycol 2006; 44: 87-92.
  15. Tan JS, Joseph WS. Common fungal infections of the feet in patients with diabetes mellitus. Drugs Aging 2004; 21: 101-112. https://doi.org/10.2165/00002512-200421020-00003