Korean Journal of Clinical Laboratory Science (대한임상검사과학회지)

Korean Society for Clinical Laboratory Science (대한임상검사과학회)
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Genotype Analysis of Human Papilloma Virus Infection in Accordance with Cytological Diagnoses

  • Park, Mi-Suk (Department of Clinical Laboratory Science, Gwangyang Health College) ;
  • Cho, Hyun-Wook (Department of Biology, College of Bio-Industry Science, Sunchon National University) ;
  • Kim, Jin-Gak (Department of Clinical Laboratory Science, Gwangyang Health College) ;
  • Bae, Nan-Young (Department of Clinical Laboratory Science, Gwangyang Health College) ;
  • Oh, Dong-Sun (Department of Clinical Laboratory Science, Gwangyang Health College) ;
  • Park, Ho-Hyun (BioMedical Laboratory Science, Mokpo Science University)
  • Received : 2015.02.27
  • Accepted : 2015.03.18
  • Published : 2015.03.30
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Abstract

We investigated whether multiple infections can be used as predictors of progression to carcinogenesis in accordance with the cytological diagnosis in women receiving abnormal cytologic diagnosis as analysis genotype and compared to single infection. HPV prevalence is highest in the age of under 30 years old woman, HPV prevalence is started to lower after 30 years old and started to increase over 60 years old as like a U-shape. The specific HPV genotypes is an important factor because increased single infection and reduced multiple infections and appeared single infection with AC in progressing carcinogenesis. HPV 16 revealed the statistical significance at the single infection in squamous cell lesions, and HPV 18 revealed the statistical significance at the single infection in adenocarcinoma with showed HPV 16, 58, 18, 52-type distribution.

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References

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