DOI QR코드

DOI QR Code

우리나라 청소년의 플라보노이드 섭취 실태: 2007~2012년 국민건강영양조사 자료를 이용하여

Estimated dietary flavonoids intake of Korean adolescent: Based on the Korea National Health and Nutrition Examination Survey 2007~2012

  • 김성아 (서울대학교 보건대학원 보건학과 보건영양학교실) ;
  • 전신영 (서울대학교 보건대학원 보건학과 보건영양학교실) ;
  • 정효지 (서울대학교 보건대학원 보건학과 보건영양학교실)
  • Kim, Seong-Ah (Division of Public Health Nutrition, Department of Public Health Science, Graduate School of Public Health, Seoul National University) ;
  • Jun, Shinyoung (Division of Public Health Nutrition, Department of Public Health Science, Graduate School of Public Health, Seoul National University) ;
  • Joung, Hyojee (Division of Public Health Nutrition, Department of Public Health Science, Graduate School of Public Health, Seoul National University)
  • 투고 : 2015.05.07
  • 심사 : 2015.11.03
  • 발행 : 2015.12.31

초록

본 연구에서는 우리나라 12~18세 청소년의 플라보노이드 섭취 실태와 그 역학적 특성을 파악하기 위해 제 4 5기 국민건강영양조사 (2007~2012) 자료의 24시간 회상법 자료와 상용식품 중 플라보노이드 함량 데이터베이스를 연계하여 1일 총 플라보노이드 및 개별 플라보노이드 (플라보놀, 플라본, 플라바논, 플라반-3-올, 안토시아니딘, 이소플라본) 섭취량을 추정하였다. 그 결과, 한국 12~18세 청소년의 1일 평균 총 플라보노이드 섭취량은 남자 청소년이 195.6 mg/d, 여자 청소년이 189.4 mg/d 였으며, 개별 플라보노이드 중에는 플라보놀, 이소플라본 순으로 섭취량이 많았다. 플라보노이드 섭취량에 따라 영양소 및 식품군의 섭취량에 뚜렷한 차이가 있었는데, 플라보노이드 섭취량이 많은 군에서 지방 섭취량과 지방 기여 에너지 섭취량이 유의하게 낮았으며, 식이섬유와 비타민 C 섭취량은 유의하게 증가하였다. 식품군 별로 살펴보았을 때, 플라보노이드 섭취량이 많은 군일수록 곡류와 육류, 우유 및 유제품 군의 섭취량이 적었고, 두류와 과일류의 섭취가 선형적으로 증가하였다. 플라보노이드 섭취량에 따른 사회인구학적 요인, 건강 관련 지표, 식생활 요인의 분포를 살펴보았을 때, 플라보노이드 섭취량이 많은 그룹일수록 여성의 비율이 더 많았으며, 허리둘레와 수축기 혈압의 평균값이 유의하게 적었다. 여러 역학연구를 통해 플라보노이드가 심혈관계 질환, 당뇨병 등 만성질환의 예방에 긍정적인 영향을 미침이 증명되었고, 청소년기의 식생활은 성인기 이후 만성질환의 발생과 연관이 있으므로, 성인기의 건강을 위해서 청소년기부터 플라보노이드가 풍부한 식생활을 하는 것이 중요할 것으로 사료된다. 청소년의 플라보노이드 섭취 실태를 확인한 본 연구에서 더 나아가 플라보노이드 섭취량과 대사지표 및 질병의 유병률 등과의 연관성에 대한 후속 연구가 필요할 것이다.

Purpose: The purpose of this study was to estimate dietary flavonoids intake of Korean adolescents. Methods: Using data from the 2007-2012 Korean National Health and Nutrition Examination Survey, a total of 3,957 subjects aged 12-18 were included in this study. We estimated individual daily intake of total flavonoid and six flavonoid classes including flavonols, flavones, flavanones, flavan-3-ols, anthocyanidins, and isoflavones by linking food consumption data with the flavonoids in the commonly consumed food database. The distribution of sociodemographic, health-related, and dietary factors according to flavonoids intake was examined. Results: Average dietary flavonoids intake of the study subjects was 195.6 mg/d in girls, and 189.4 mg/d in boys. The highest flavonoids intake group consumed significantly more fiber, vitamin C, legumes, fruits, and vegetables (p < 0.01) and less fat, grains, meats and dairy foods than other lower consumption groups (p < 0.001). Dietary flavonoid intake showed negative correlation with waist circumference and systolic blood pressure (p < 0.05). Conclusion: This study provided basic data for estimation of flavonoids intake of Korean adolescents. Further research will be required for analysis of the association of flavonoids intake and health-related factors such as cardiovascular risk factors.

키워드

참고문헌

  1. Lifshitz F, Tarim O, Smith MM. Nutrition in adolescence. Endocrinol Metab Clin North Am 1993; 22(3): 673-683.
  2. Kim KW, Shin EM. A study on nutrition knowledge, nutritional attitudes, dietary behavior and dietary intake by weight control attempt among middle school female students. Korean J Community Nutr 2002; 7(1): 23-31.
  3. Kwon WJ, Chang KJ, Kim SK. Comparison of nutrient intake, dietary behavior, perception of body image and iron nutritional status among female high school students of urban and rural areas in Kyunggi-do. Korean J Nutr 2002; 35(1): 90-101.
  4. An GS, Shin DS. A comparison of the food and nutrient intake of adolescents between urban areas and islands in south Kyungnam. Korean J Community Nutr 2001; 6(3): 271-281.
  5. Oh K, Jang MJ, Lee NY, Moon JS, Lee CG, Yoo MH, Kim YT. Prevalence and trends in obesity among Korean children and adolescents in 1997 and 2005. Korean J Pediatr 2008; 51(9): 950-955. https://doi.org/10.3345/kjp.2008.51.9.950
  6. Baek SH. Effect of % body fat, physical fitness on impact on cardiovascular risk index in female middle-school students. Korean J Sports Sci 2012; 21(2): 1009-1017.
  7. Chang JH, Kim DH, Kim HS, Choi IK, Cheong MY, Kim DK. Prevalence of metabolic syndrome in obese children. Korean J Pediatr 2004; 47(11): 1149-1156.
  8. Ministry of Health and Welfare (KR). The third national health promotion plan (2011-2020). Seoul: Ministry of Health and Welfare; 2011.
  9. Ministry of Health and Welfare, Korea Centers for Disease Control and Prevention. Korea Health Statistics 2011: Korea National Health and Nutrition Examination Survey (KNHANES V-2). Cheongwon: Korea Centers for Disease Control and Prevention; 2012.
  10. Doll R. An overview of the epidemiological evidence linking diet and cancer. Proc Nutr Soc 1990; 49(2): 119-131. https://doi.org/10.1079/PNS19900018
  11. Hertog MG, van Poppel G, Verhoven D. Potentially anticarcinogenic secondary metabolites from fruit and vegetables. In: Tomas-Barberan FA, Robins RJ, editors. Phytochemistry of Fruit and Vegetables. Oxford: Clarendon Press; 1997. p.313-330.
  12. Hertog MG, Feskens EJ, Hollman PC, Katan MB, Kromhout D. Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen elderly study. Lancet 1993; 342(8878): 1007-1011. https://doi.org/10.1016/0140-6736(93)92876-U
  13. Hertog MG, Kromhout D, Aravanis C, Blackburn H, Buzina R, Fidanza F, Giampaoli S, Jansen A, Menotti A, Nedeljkovic S, Pekkarinen M, Simic BS, Toshima H, Feskens EJ, Hollman PC, Katan MB. Flavonoid intake and long-term risk of coronary heart disease and cancer in the seven countries study. Arch Intern Med 1995; 155(4): 381-386. https://doi.org/10.1001/archinte.1995.00430040053006
  14. Hertog MG, Sweetnam PM, Fehily AM, Elwood PC, Kromhout D. Antioxidant flavonols and ischemic heart disease in a Welsh population of men: the Caerphilly study. Am J Clin Nutr 1997; 65(5): 1489-1494. https://doi.org/10.1093/ajcn/65.5.1489
  15. Chun OK, Kim DO, Smith N, Schroeder D, Han JT, Lee CY. Daily consumption of phenolics and total antioxidant capacity from fruit and vegetables in the American diet. J Sci Food Agric 2005; 85(10): 1715-1724. https://doi.org/10.1002/jsfa.2176
  16. Chun OK, Chung SJ, Song WO. Estimated dietary flavonoid intake and major food sources of U.S. adults. J Nutr 2007; 137(5): 1244-1252. https://doi.org/10.1093/jn/137.5.1244
  17. Graf BA, Milbury PE, Blumberg JB. Flavonols, flavones, flavanones, and human health: epidemiological evidence. J Med Food 2005; 8(3): 281-290. https://doi.org/10.1089/jmf.2005.8.281
  18. Kris-Etherton PM, Keen CL. Evidence that the antioxidant flavonoids in tea and cocoa are beneficial for cardiovascular health. Curr Opin Lipidol 2002; 13(1): 41-49. https://doi.org/10.1097/00041433-200202000-00007
  19. O'Byrne DJ, Devaraj S, Grundy SM, Jialal I. Comparison of the antioxidant effects of Concord grape juice flavonoids alphatocopherol on markers of oxidative stress in healthy adults. Am J Clin Nutr 2002; 76(6): 1367-1374. https://doi.org/10.1093/ajcn/76.6.1367
  20. Vinson JA, Su X, Zubik L, Bose P. Phenol antioxidant quantity and quality in foods: fruits. J Agric Food Chem 2001; 49(11): 5315- 5321. https://doi.org/10.1021/jf0009293
  21. Rein D, Paglieroni TG, Wun T, Pearson DA, Schmitz HH, Gosselin R, Keen CL. Cocoa inhibits platelet activation and function. Am J Clin Nutr 2000; 72(1): 30-35. https://doi.org/10.1093/ajcn/72.1.30
  22. Vita JA. Polyphenols and cardiovascular disease: effects on endothelial and platelet function. Am J Clin Nutr 2005; 81(1 Suppl): 292S-297S. https://doi.org/10.1093/ajcn/81.1.292S
  23. Yao LH, Jiang YM, Shi J, Tomas-Barberan FA, Datta N, Singanusong R, Chen SS. Flavonoids in food and their health benefits. Plant Foods Hum Nutr 2004; 59(3): 113-122. https://doi.org/10.1007/s11130-004-0049-7
  24. Beatty S, Koh H, Phil M, Henson D, Boulton M. The role of oxidative stress in the pathogenesis of age-related macular degeneration. Surv Ophthalmol 2000; 45(2): 115-134. https://doi.org/10.1016/S0039-6257(00)00140-5
  25. Lee SA, Shu XO, Li H, Yang G, Cai H, Wen W, Ji BT, Gao J, Gao YT, Zheng W. Adolescent and adult soy food intake and breast cancer risk: results from the Shanghai Women's Health Study. Am J Clin Nutr 2009; 89(6): 1920-1926. https://doi.org/10.3945/ajcn.2008.27361
  26. Dominguez C, Ruiz E, Gussinye M, Carrascosa A. Oxidative stress at onset and in early stages of type 1 diabetes in children and adolescents. Diabetes Care 1998; 21(10): 1736-1742. https://doi.org/10.2337/diacare.21.10.1736
  27. Jun S, Shin S, Joung H. Estimation of dietary flavonoid intake and major food sources of Korean adults. Br J Nutr. Forthcoming 2015.
  28. Knekt P, Jarvinen R, Reunanen A, Maatela J. Flavonoid intake and coronary mortality in Finland: a cohort study. BMJ 1996; 312 (7029): 478-481. https://doi.org/10.1136/bmj.312.7029.478
  29. Mink PJ, Scrafford CG, Barraj LM, Harnack L, Hong CP, Nettleton JA, Jacobs DR Jr. Flavonoid intake and cardiovascular disease mortality: a prospective study in postmenopausal women. Am J Clin Nutr 2007; 85(3): 895-909. https://doi.org/10.1093/ajcn/85.3.895
  30. McCullough ML, Peterson JJ, Patel R, Jacques PF, Shah R, Dwyer JT. Flavonoid intake and cardiovascular disease mortality in a prospective cohort of US adults. Am J Clin Nutr 2012; 95(2): 454-464. https://doi.org/10.3945/ajcn.111.016634
  31. Ministry of Health and Welfare, Korea Centers for Disease Control and Prevention. Korea Health Statistics 2007: Korea National Health and Nutrition Examination Survey (KNHANES IV-1) [Internet]. Cheongwon: Korea Centers for Disease Control and Prevention; 2008 [cited 2014 Sep 1]. Available from: https:// knhanes.cdc.go.kr/knhanes/index.do.
  32. Ministry of Health and Welfare, Korea Centers for Disease Control and Prevention. Korea Health Statistics 2008: Korea National Health and Nutrition Examination Survey (KNHANES IV-2) [Internet]. Cheongwon: Korea Centers for Disease Control and Prevention; 2009 [cited 2014 Sep 1]. Available from: https://knhanes.cdc.go.kr/knhanes/index.do.
  33. Ministry of Health and Welfare, Korea Centers for Disease Control and Prevention. Korea Health Statistics 2009: Korea National Health and Nutrition Examination Survey (KNHANES IV-3) [Internet]. Cheongwon: Korea Centers for Disease Control and Prevention; 2010 [cited 2014 Sep 1]. Available from: https://knhanes.cdc.go.kr/knhanes/index.do.
  34. Ministry of Health and Welfare, Korea Centers for Disease Control and Prevention. Korea Health Statistics 2010: Korea National Health and Nutrition Examination Survey (KNHANES V-1)[Internet]. Cheongwon: Korea Centers for Disease Control and Prevention; 2011 [cited 2014 Sep 1]. Available from: https://knhanes.cdc.go.kr/knhanes/index.do.
  35. Ministry of Health and Welfare, Korea Centers for Disease Control and Prevention. Korea Health Statistics 2012: Korea National Health and Nutrition Examination Survey (KNHANES V-3) [Internet]. Cheongwon: Korea Centers for Disease Control and Prevention; 2013 [cited 2014 Sep 1]. Available from: https://knhanes.cdc.go.kr/knhanes/index.do.
  36. Knaze V, Zamora-Ros R, Lujan-Barroso L, Romieu I, Scalbert A, Slimani N, Riboli E, van Rossum CT, Bueno-de-Mesquita HB, Trichopoulou A, Dilis V, Tsiotas K, Skeie G, Engeset D, Quiros JR, Molina E, Huerta JM, Crowe F, Wirfäl E, Ericson U, Peeters PH, Kaaks R, Teucher B, Johansson G, Johansson I, Tumino R, Boeing H, Drogan D, Amiano P, Mattiello A, Khaw KT, Luben R, Krogh V, Ardanaz E, Sacerdote C, Salvini S, Overvad K, Tjonneland A, Olsen A, Boutron-Ruault MC, Fagherazzi G, Perquier F, Gonzalez CA. Intake estimation of total and individual flavan-3-ols, proanthocyanidins and theaflavins, their food sources and determinants in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Br J Nutr 2012; 108(6): 1095-1108. https://doi.org/10.1017/S0007114511006386
  37. Casagrande SS, Wang Y, Anderson C, Gary TL. Have Americans increased their fruit and vegetable intake? The trends between 1988 and 2002. Am J Prev Med 2007; 32(4): 257-263. https://doi.org/10.1016/j.amepre.2006.12.002
  38. Kim JH, Lee MJ, Yang IS, Moon SJ. Analysis of factors affecting Korean eating behavior. Korean J Diet Cult 1992; 7(1): 1-8.
  39. Galleano M, Calabro V, Prince PD, Litterio MC, Piotrkowski B, Vazquez-Prieto MA, Miatello RM, Oteiza PI, Fraga CG. Flavonoids and metabolic syndrome. Ann N Y Acad Sci 2012; 1259: 87-94. https://doi.org/10.1111/j.1749-6632.2012.06511.x
  40. Steffen Y, Gruber C, Schewe T, Sies H. Mono-O-methylated flavanols and other flavonoids as inhibitors of endothelial NADPH oxidase. Arch Biochem Biophys 2008; 469(2): 209-219. https://doi.org/10.1016/j.abb.2007.10.012
  41. Schroeter H, Heiss C, Balzer J, Kleinbongard P, Keen CL, Hollenberg NK, Sies H, Kwik-Uribe C, Schmitz HH, Kelm M. (-)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans. Proc Natl Acad Sci U S A 2006; 103(4): 1024-1029. https://doi.org/10.1073/pnas.0510168103
  42. Cassidy A, O'Reilly EJ, Kay C, Sampson L, Franz M, Forman JP, Curhan G, Rimm EB. Habitual intake of flavonoid subclasses and incident hypertension in adults. Am J Clin Nutr 2011; 93(2): 338-347. https://doi.org/10.3945/ajcn.110.006783
  43. Yang YJ, Kim YJ, Yang YK, Kim JY, Kwon O. Dietary flavan-3- ols intake and metabolic syndrome risk in Korean adults. Nutr Res Pract 2012; 6(1): 68-77. https://doi.org/10.4162/nrp.2012.6.1.68
  44. Holt EM, Steffen LM, Moran A, Basu S, Steinberger J, Ross JA, Hong CP, Sinaiko AR. Fruit and vegetable consumption and its relation to markers of inflammation and oxidative stress in adolescents. J Am Diet Assoc 2009; 109(3): 414-421. https://doi.org/10.1016/j.jada.2008.11.036
  45. Kim SH, Cho SW, Hwang SS, Ahn M, Lee D, Kang SW, Park YK. Increased whole grain, fruits and vegetable intake reduced oxidative stress in high school students. Korean J Nutr 2012; 45(5): 452-461. https://doi.org/10.4163/kjn.2012.45.5.452
  46. Ness AR, Maynard M, Frankel S, Smith GD, Frobisher C, Leary SD, Emmett PM, Gunnell D. Diet in childhood and adult cardiovascular and all cause mortality: the Boyd Orr cohort. Heart 2005; 91(7): 894-898. https://doi.org/10.1136/hrt.2004.043489
  47. The Korean Nutrition Society. Dietary reference intakes for Koreans. 1st revision. Seoul: The Korean Nutrition Society; 2010.
  48. Kim JH, Kim YS, Kim Y, Kang MS. Fruit and vegetable consumption and factors affecting fruit and vegetable consumption of school children and adolescents: findings from focus-group interviews with school nutrition teachers and nutritionists. Korean J Community Living Sci 2013; 24(4): 567-581. https://doi.org/10.7856/kjcls.2013.24.4.567

Cited by

  1. Association of total dietary antioxidant capacity with oxidative stress and metabolic markers among patients with metabolic syndrome vol.50, pp.3, 2017, https://doi.org/10.4163/jnh.2017.50.3.246
  2. Estimated Flavonoid Intake and Analysis of Relevance of Cardiovascular Risk Factors for Pre- and Post-Menopausal Women in Daegu and Gyeongbuk : Based on The Korean National Health and Nutrition Examin vol.29, pp.6, 2015, https://doi.org/10.17495/easdl.2019.12.29.6.538
  3. Estimated intake and major food sources of flavonoids among Australian adolescents vol.59, pp.8, 2020, https://doi.org/10.1007/s00394-020-02218-z