한국안광학회지 (Journal of Korean Ophthalmic Optics Society)

한국안광학회 (The Korean Ophthalmic Optics Society)
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4가지 건성안 분석방법(OQAS test, TBUT, Schirmer test, McMonnies test)의 비교

Comparison Among the Four Examination Methods for Dry Eye (OQAS test, TBUT, Schirmer Test, McMonnies test)

  • 박창원 (가톨릭대학교 의과대학 시과학연구소) ;
  • 김효진 (백석대학교 보건학부 안경광학과)
  • Park, Chang Won (Laboratory of Visual Science, The Catholic University of Korea) ;
  • Kim, Hyojin (Dept. of Optometry, Division of Health Science, Baekseok University)
  • Received : 2015.11.03
  • Accepted : 2015.12.08
  • Published : 2015.12.31
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⟨ 이전 논문 다음 논문 ⟩

Abstract

목적: 객관적 검안기기인 OQAS (Optical Quality Analysis System)를 이용하여 눈물막의 불안정성에 따른 객관적 산란지수의 변화를 연속적으로 관찰하고, 이 측정값과 눈물막파괴시간, 쉬르머테스트 및 맥모니테스트와의 상관성을 알아보고자 하였다. 방법: 대학생 82명($21.51{\pm}3.97$세, 남45명, 여37명), 147안을 대상으로 눈물막파괴시간, 쉬르머테스트, 맥모니테스트를 실시하였고, OQAS의 연속 측정방법을 이용하여 순목 직후 15초 동안 매초간의 객관적 산란지수를 측정하였다. 결과: 정상안과 건성안 군의 객관적 산란지수(OSI value)는 각각 $2.13{\pm}1.16$와 $3.76{\pm}1.42$로 통계적으로 유의한 차이를 보였다(p<0.05). 모든 대상자는 측정 시간이 경과할수록 객관적 산란지수가 증가하였고, 순목 직후 매초 측정된 객관적 산란지수는 6초와 7초 사이에 변화량이 가장 크게 증가하였다(p<0.05). 객관적 산란지수 cut off 30%(sec.) 결과는 눈물막파괴시간(r = 0.855, p = 0.000), 맥모니테스트(r = -0.351, p = 0.003), 쉬르머테스트(r = 0.316, p = 0.012) 순으로 상관성이 있는 것으로 나타났다. 결론: OQAS의 연속측정 방법은 기존의 건성안 검사법과 상관성이 높았다. 객관적 산란지수를 이용한 OQAS 검사방법은 환자의 눈물막 상태를 객관적으로 평가하는데 유용하게 사용될 것으로 생각된다.

Purpose: To evaluate the changes of OSI value according to tear-film instability measured serially by OQAS(Optical Quality Analysis System, Visiometrics, Spain) every seconds. The presented study analyzed the relationship of the OQAS parameter with the results of the tear-film break-up time, Schirmer test, and the McMonies score. Methods: 147 eyes of 82 subjects were randomly selected from university students (age: $21.51{\pm}3.97$, male 45, female 37). Subjects were measured tear-film break-up time, Schirmer test, McMonies score and once every second for 15 seconds after blinking by continuous measurements from OQAS system. Results: The normal eye groups presented OSI values of $2.13{\pm}1.16$ while the dry eye groups had OSI values of $3.76{\pm}1.42$. Therefore, a significant difference between the normal eye group and dry eye group was discovered (p<0.05). In addition, the OSI value of all subjects increased over time. The OSI value, which was measured every second after blinking occurred, significantly increased between 6 seconds and 7 seconds after the start of the measurement (p<0.05). OSI cut off of 30% (sec.) showed a greater correlation; TBUT (r = 0.855, p = 0.000), McMonies test (r = -0.351, p = 0.003), Schirmer (r = 0.316, p = 0.012). Conclusions: Continuous measurement of OQAS showed a high correlation with the value of the existing dry eye tests. Therefore, Analysis of OSI values by utilization of OQAS could be useful in objectively evaluation of tear film in patients.

Keywords

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