Primary Angiosarcoma of Accessory Parotid Gland : A Case Report of Long Term Follow-up

부이하선에 생긴 원발성 혈관육종 1예의 장기추적

  • Lee, Hyo Won (Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Catholic University of Daegu) ;
  • Kim, Deok Su (Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Catholic University of Daegu) ;
  • Jang, Gyu Ho (Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Catholic University of Daegu) ;
  • Kim, Jeong Kyu (Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Catholic University of Daegu)
  • 이효원 (대구가톨릭대학교 의과대학 이비인후과학교실) ;
  • 김덕수 (대구가톨릭대학교 의과대학 이비인후과학교실) ;
  • 장규호 (대구가톨릭대학교 의과대학 이비인후과학교실) ;
  • 김정규 (대구가톨릭대학교 의과대학 이비인후과학교실)
  • Received : 2015.08.31
  • Accepted : 2015.10.19
  • Published : 2015.11.30

Abstract

Angiosarcoma is a rare and highly malignant neoplasm which develops from the endothelium of blood vessels. A few cases of primary angiosarcoma of the parotid gland have been reported. However, there is no report of primary angiosarcoma of the accessory parotid gland. In this case, we report a primary angiosarcoma of the accessory parotid gland in a 45-year-old man with growing cheek mass. Ultrasonography revealed a $2.0{\times}2.6cm$ sized homogeneous hypoechoic mass and computed tomography showed a contrast enhanced homogeneous mass. Fine needle aspiration biopsy suggested a benign tumor. The mass was completely excised with a minimal vertical incision. The histopathology showed anastomosing vascular channels lined by atypical endothelial cells and many branching vessels with staghorn appearance with positive immunohistochemical staining for CD34, a highly specific endothelial marker. The patient underwent postoperative radiotherapy and was followed for 8 years without recurrence and metastasis.

Keywords

References

  1. Lydiatt WM, Shaha AR, Shah JP. Angiosarcoma of the head and neck. Am J Surg. 1994;168(5):451-454. https://doi.org/10.1016/S0002-9610(05)80097-2
  2. Patel SH, Hayden RE, Hinni ML, Wong WW, Foote RL, Milani S, et al. Angiosarcoma of the Scalp and face the Mayo clinic experience. JAMA Otolaryngol Head Neck Surg. 2015;141(4):335-340. https://doi.org/10.1001/jamaoto.2014.3584
  3. Johnson FE, Spiro RH. Tumors arising in accessory parotid tissue. Am J Surg. 1979;138:576-578. https://doi.org/10.1016/0002-9610(79)90422-7
  4. Newberry TR, Kaufmann CR, Miller FR. Review of accessory parotid gland tumors: Pathologic incidence and surgical management. Am J Otolaryngol. 2014;35(1):48-52. https://doi.org/10.1016/j.amjoto.2013.08.018
  5. Chung YM, Kang YK, Chang JS, Choi IS. Primary angiosarcoma of the parotid gland. Korean J Otorhinolaryngol-Head Neck Surg. 2008;51:838-841.
  6. Frommer J. The human accessory parotid gland: its incidence, nature, and significance. Oral Surg Oral Med Oral Pathol. 1977;43(5):671-676. https://doi.org/10.1016/0030-4220(77)90049-4
  7. Toh H, Kodama J, Fukuda J, Rittman B, Mackenzie I. Incidence and histology of human accessory parotid glands. Anat Rec. 1993;236(3):586-590. https://doi.org/10.1002/ar.1092360319
  8. Rouhani P, Fletcher CD, Devesa SS, Toro JR. Cutaneous soft tissue sarcoma incidence patterns in the US: an analysis of 12,114 cases. Cancer. 2008;113(3):616-627. https://doi.org/10.1002/cncr.23571
  9. Fujii Y, Koibuchi-Yamaoka H, Taniguchi N, Yasuda Y, Nagai H. Metastasis from a primary angiosarcoma of the scalp to the colon: sonographic and CT findings. J Clin Ultrasound. 2008;36(2):110-112. https://doi.org/10.1002/jcu.20363
  10. Iguchi H, Wada T, Matsushita N, Oishi M, Teranishi Y, Yamane H. Evaluation of usefulness of fine-needle aspiration cytology in the diagnosis of tumours of the accessory parotid gland: a preliminary analysis of a case series in Japan. Acta Otolaryngol. 2014;134(7):768-770. https://doi.org/10.3109/00016489.2014.905704
  11. Perzik SL, White IL. Surgical management of preauricular tumors of the accessory parotid apparatus. Am J Surg. 1966;112:498-503. https://doi.org/10.1016/0002-9610(66)90311-4
  12. De Riu G, Meloni SM, Massarelli O, Tullio A. Management of midcheek masses and tumors of the accessory parotid gland. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011;111(5):5-11. https://doi.org/10.1016/S1079-2104(11)00032-1
  13. Letsa I, Benson C, Al-Muderis O, Judson I. Angiosarcoma of the face and scalp: Effective systemic treatment in the older patient. J Geriatr Oncol. 2014;5(3):276-280. https://doi.org/10.1016/j.jgo.2014.02.004
  14. Aust MR, Olsen KD, Lewis JE, Nascimento AG, Meland NB, Foote RL, et al. Angiosarcomas of the head and neck: Clinical and pathologic characteristics. Ann Otol Rhinol Laryngol. 1997;106(11):943-951. https://doi.org/10.1177/000348949710601110
  15. Fanburg-Smith JC, Furlong MA, Childers EL. Oral and salivary gland angiosarcoma a clinicopathologic study of 29 cases. Mod Pathol. 2003;16(3):263-271. https://doi.org/10.1097/01.MP.0000056986.08999.FD