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Symmetrical Peripheral Gangrene Complicating Escherichia coli Sepsis Associated with Antiphospholipid Antibodies in Lupus Nephritis

루푸스 신염 환자에서 항인지질 항체와 연관된 감염 후 칭적 말초 괴저

  • Lee, Jae Sung (Department of Internal Medicine, Seoul Red Cross Hospital) ;
  • Seong, Jee Seok (Department of Internal Medicine, Seoul Red Cross Hospital) ;
  • Woo, Yong Moon (Department of Internal Medicine, Seoul Red Cross Hospital) ;
  • Cho, Young Jun (Department of Internal Medicine, Seoul Red Cross Hospital) ;
  • Jeong, Beom Jin (Department of Internal Medicine, Seoul Red Cross Hospital) ;
  • Kang, Han Na (Department of Pathology, Seoul Red Cross Hospital) ;
  • Kim, Su-Jung (Division of Public Health Medical Service, Seoul National University Hospital, Seoul University College of Medicine)
  • 이재성 (서울적십자병원 내과) ;
  • 성지석 (서울적십자병원 내과) ;
  • 우용문 (서울적십자병원 내과) ;
  • 조영준 (서울적십자병원 내과) ;
  • 정범진 (서울적십자병원 내과) ;
  • 강한나 (서울적십자병원 병리과) ;
  • 김수정 (서울대학교 의과대학 서울대학교병원 공공보건의료사업단)
  • Received : 2013.12.03
  • Accepted : 2014.03.04
  • Published : 2014.09.01

Abstract

Antiphospholipid syndrome (APS) is an autoimmune disease that involves vascular thrombosis and pregnancy morbidity associated with elevated titers of antiphospholipid antibodies. APS can affect any organ and has a variety of clinical manifestations. Infections can be associated with thrombotic events in APS, including the potentially fatal subset catastrophic APS. We report a case of extensive symmetrical peripheral gangrene complicating Escherichia coli sepsis associated with antiphospholipid antibodies in a patient with lupus nephritis.

저자들은 요로감염 패혈증 후 다발성 장기부전을 보인 루푸스 신염 환자에서 항인지질 항체와 연관된 광범위한 대칭적 말초 괴저를 경험하였고 항생제와 고용량 prednisolone, 항응고제 사용으로 호전시킨 1예를 문헌고찰과 함께 보고하는 바이다.

Keywords

References

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