The Korean Journal of Medicine

  • 제87권2호
  • /
  • Pages.229-233
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  • 2014
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  • 1738-9364(pISSN)
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  • 2289-0769(eISSN)
대한내과학회 (The Korean Association of Internal Medicine)
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헬리코박터 제균 치료 후 완전 관해된 방광의 원발성 점막연관 림프조직 림프종 1예

A Case of Complete Remission of Mucosa-associated Lymphoid Tissue Lymphoma of the Urinary Bladder after Eradication of Helicobacter Pylori

  • 이선표 (울산대학교 의과대학 서울아산병원 내과) ;
  • 주명수 (울산대학교 의과대학 서울아산병원 비뇨기과) ;
  • 류민희 (울산대학교 의과대학 서울아산병원 내과) ;
  • 송민정 (울산대학교 의과대학 서울아산병원 병리과) ;
  • 서세영 (울산대학교 의과대학 서울아산병원 내과) ;
  • 정유문 (울산대학교 의과대학 서울아산병원 내과) ;
  • 서명숙 (울산대학교 의과대학 서울아산병원 내과) ;
  • 허주영 (울산대학교 의과대학 서울아산병원 병리과)
  • Lee, Sunpyo (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Choo, Myung-Soo (Department of Urology, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Ryu, Min-Hee (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Song, Minjeong (Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Seo, Seyoung (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Jeong, Yumun (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Seo, Myeongsook (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Huh, Jooryung (Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine)
  • 투고 : 2013.12.19
  • 심사 : 2014.02.21
  • 발행 : 2014.08.01
⟨ 이전 논문 다음 논문 ⟩

초록

방광에서 발생한 원발성 MALT 림프종은 드문 질환으로 만성 방광염과 유사한 임상 증상을 갖고 국내에서 지금까지 보고된 사례는 1예뿐이다. 저자들은 혈뇨를 주소로 내원한 중년 여성에서 만성 방광염에서 병발한 MALT 림프종을 진단하고 방사선 치료나 항암화학요법이 아닌 항생제 투여를 통해 완치하였기에 문헌고찰과 함께 보고하는 바이다.

Primary lymphoma of the urinary bladder is rare, comprising 0.2% of extranodal lymphomas. The predominant subtype of mucosa-associated lymphoid tissue (MALT) is extranodal marginal zone lymphoma. We report a case of MALT lymphoma of the urinary bladder in a 53-year-old female patient presenting with a five-year history of persistent hematuria and urinary frequency. A cystoscopy revealed multiple nodular lesions at the posterior wall and trigone of the bladder. The tissue obtained by cold-cup biopsy revealed lymphoid infiltration consistent with low-grade MALT lymphoma. Image studies revealed that the tumor originated from the urinary bladder and there was no evidence of metastases. The patient was positive for a rapid urease test. Because of the relationship between gastric MALT lymphoma and Helicobacter pylori, the patient was treated with antibiotics to eradicate Helicobacter pylori. The lymphoma subsequently disappeared and the patient has remained in persistent complete remission for eight years.

키워드

참고문헌

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