DOI QR코드

DOI QR Code

전신경화증 환자에서 발생한 동기능부전증후군 1예

A Case of Sick Sinus Syndrome in a Patient with Systemic Sclerosis

  • 김동현 (조선대학교 의학전문대학원 내과학교실) ;
  • 김성중 (조선대학교 의학전문대학원 내과학교실) ;
  • 소중해 (조선대학교 의학전문대학원 내과학교실) ;
  • 임균섭 (조선대학교 의학전문대학원 내과학교실) ;
  • 김형호 (조선대학교 의학전문대학원 내과학교실) ;
  • 김현숙 (순천향대학교 의학전문대학원 내과학교실) ;
  • 김윤성 (조선대학교 의학전문대학원 내과학교실)
  • Kim, Dong Hyun (Department of Internal Medicine, Chosun University School of Medicine) ;
  • Kim, Sung Jung (Department of Internal Medicine, Chosun University School of Medicine) ;
  • So, Jung Hae (Department of Internal Medicine, Chosun University School of Medicine) ;
  • Lim, Gyun Seop (Department of Internal Medicine, Chosun University School of Medicine) ;
  • Kim, Hyung Ho (Department of Internal Medicine, Chosun University School of Medicine) ;
  • Kim, Hyun-Sook (Department of Internal Medicine, Sunchunhyang University College of Medicine) ;
  • Kim, Yun Sung (Department of Internal Medicine, Chosun University School of Medicine)
  • 투고 : 2013.04.12
  • 심사 : 2013.08.05
  • 발행 : 2014.01.01

초록

Systemic sclerosis (SSc) is characterized by the presence of microvascular disease and various patterns of cutaneous and parenchymal fibrosis. Manifestation of SSc may occur in numerous tissues and organs and can be particularly problematic when present in the lungs, kidneys or heart. Cardiac involvement in SSc includes pericarditis, myocardial disease, conduction abnormalities, and arrhythmia. Sick sinus syndrome is described as a combination of symptoms (dizziness, confusion, fatigue, syncope and congestive heart failure) caused by sinus node dysfunction and manifested by marked sinus bradycardia, sinoatrial block, or sinus arrest. Sinus node dysfunction is most often seen in the elderly but also, rarely, in systemic amyloidosis and connective tissue disease. Sick sinus syndrome is rarely found in patients with SSc, of which there has been only one case report, according to a review of the literature. Therefore, we report a case of sick sinus syndrome in a 71-year-old female with SSc.

키워드

과제정보

연구 과제 주관 기관 : Chosun University

참고문헌

  1. Janosik DL, Osborn TG, Moore TL, Shah DG, Kenney RG, Zuckner J. Heart disease in systemic sclerosis. Semin Arthritis Rheum 1989;19:191-200. https://doi.org/10.1016/0049-0172(89)90032-2
  2. Follansbee WP, Curtiss EI, Rahko PS, et al. The electrocardiogram in systemic sclerosis (scleroderma): study of 102 consecutive cases with functional correlations and review of the literature. Am J Med 1985;79:183-192. https://doi.org/10.1016/0002-9343(85)90008-7
  3. Kahan A, Coghlan G, McLaughlin V. Cardiac complications of systemic sclerosis. Rheumatology (Oxford) 2009;48(Suppl 3):iii45-48.
  4. Inazumi T, Tajima S, Ando T, Shimada M. A case of CREST syndrome associated with sick sinus syndrome. J Dermatol 1995;22:801-803. https://doi.org/10.1111/j.1346-8138.1995.tb03925.x
  5. Oe K, Mori K, Gommori S, Konno T, Fujino N, Yamagishi M. Syncope due to paroxysmal atrioventricular block in a patient with systemic sclerosis: a case report. Angiology 2008;59:769-771. https://doi.org/10.1177/0003319707307216
  6. Plastiras SC, Toumanidis ST. Systemic sclerosis: the heart of the matter. Hellenic J Cardiol 2012;53:287-300.
  7. Seferovic PM, Ristic AD, Maksimovic R, et al. Cardiac arrhythmias and conduction disturbances in autoimmune rheumatic diseases. Rheumatology (Oxford) 2006;45(Suppl 4):iv39-42. https://doi.org/10.1093/rheumatology/kel315
  8. Volta U, Villecco AS, Bianchi FB, et al. Antibodies to cardiac conducting tissue in progressive systemic sclerosis. Clin Exp Rheumatol 1985;3:131-135.
  9. Adan V, Crown LA. Diagnosis and treatment of sick sinus syndrome. Am Fam Physician 2003;67:1725-1732.
  10. Andrew E. Epstein, John P, et al. ACC/AHA/HRS 2008 guidelines for device-based therapy of cardiac rhythm abnormalities. J Am Coll Cardiol 2008;51(21):e1-62. https://doi.org/10.1016/j.jacc.2008.02.032