The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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Severe Fever with Thrombocytopenia Syndrome

중증열성혈소판감소증후군

  • Kim, Kye-Hyung (Department of Internal Medicine, Seoul National University College of Medicine) ;
  • Oh, Myoung-Don (Department of Internal Medicine, Seoul National University College of Medicine)
  • 김계형 (서울대학교 의과대학 내과학교실) ;
  • 오명돈 (서울대학교 의과대학 내과학교실)
  • Published : 2014.03.01
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Abstract

Severe fever with thrombocytopenia syndrome (SFTS) is firstly reported in China in 2011. It is an emerging infectious disease in China, Japan and South Korea. It is caused by novel bunyavirus, called SFTS virus. The vector of SFTS is Haemaphysalis longicornis tick and domesticated animals may serve as intermediate hosts. The clinical manifestations of SFTS are fever, vomiting, diarrhea, thrombocytopenia and leukopenia. In severe cases, multiple organ failure, disseminated intravascular coagulopathy, and central nervous systems manifestation are present. The case-fatality rate is 6-30%. There is no effective antiviral therapy and supportive care is the main treatment.

Keywords

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