The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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A Case of Alveolar Adenoma Involving Multiple Lung Nodules

다발성 폐 결절로 발견된 꽈리샘종 1예

  • Lee, Dong Seok (Department of Internal Medicine, Gangneung Asan Medical Center, University of Ulsan College of Medicine) ;
  • Hwang, Min Sik (Department of Internal Medicine, Gangneung Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lim, Jae Min (Department of Internal Medicine, Gangneung Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Mi Hye (Department of Internal Medicine, Gangneung Asan Medical Center, University of Ulsan College of Medicine) ;
  • Jung, Bock Hyun (Department of Internal Medicine, Gangneung Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kang, Gil Hyun (Department of Pathology, Gangneung Asan Medical Center, University of Ulsan College of Medicine) ;
  • Yoo, Dong-Kon (Department of Thoracis and Cardiovascular Surgery, Gangneung Asan Medical Center, University of Ulsan College of Medicine)
  • 이동석 (울산대학교 의과대학 강릉아산병원 내과) ;
  • 황민식 (울산대학교 의과대학 강릉아산병원 내과) ;
  • 임재민 (울산대학교 의과대학 강릉아산병원 내과) ;
  • 김미혜 (울산대학교 의과대학 강릉아산병원 내과) ;
  • 정복현 (울산대학교 의과대학 강릉아산병원 내과) ;
  • 강길현 (울산대학교 의과대학 강릉아산병원 병리과) ;
  • 유동곤 (울산대학교 의과대학 강릉아산병원 흉부외과)
  • Received : 2013.11.20
  • Accepted : 2014.01.07
  • Published : 2014.05.01
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Abstract

Alveolar adenoma is a very rare benign intraparenchymal lung tumor originating from type II pneumocytes. It can be mistaken for other benign tumors or lung cancer in radiological images. It is especially difficult to distinguish alveolar adenoma from sclerosing hemangioma. A small aspiration biopsy specimen, such as with percutaneous needle aspiration, is insufficient for a pathological diagnosis. Surgical resection is the only method by which a pathological diagnosis can be made and the disease treated. An alveolar adenoma presenting as multiple nodules is very rare and has to our knowledge not been reported in Korea previously. Here, we report a case of alveolar adenoma in multiple nodules in a 57-year-old female and review the literature.

꽈리샘종은 폐에서 발생하는 매우 드문 양성종양으로 영상의학적 소견과 경피적 흉부 세침흡인생검으로는 진단이 어렵고 수술적 절제를 통한 조직학적 소견 및 면역화학 검사를 통한 정확한 진단이 필요하다. 현재까지 꽈리샘종은 한국에서 보고된 증례가 없으며 더욱이 다발성 결절로 발현된 경우는 전 세계적으로도 매우 희귀하다. 본 연구자들은 기침을 주소로 내원한 57세 여자 환자에서 흉부 X-선상 두 개의 폐 결절을 발견하여 비디오보조흉강경수술을 통해 진단된 꽈리샘종을 경험하였기에 보고하며 향후 단일 폐 결절 및 다발성 폐 결절 감별진단에 꽈리샘종이 포함되어야 할 것으로 사료된다.

Keywords

References

  1. Yousem SA, Hochholzer L. Alveolar adenoma. Hum Pathol 1986;17:1066-1071. https://doi.org/10.1016/S0046-8177(86)80092-2
  2. Beasley MB, Brambilla E, Travis WD. The 2004 World Health Organization classification of lung tumors. Semin Roentgenol 2005;40:90-97. https://doi.org/10.1053/j.ro.2005.01.001
  3. Bhavsar T, Uppal G, Travaline JM, Gaughan C, Huang Y, Khurana JS. An unusual case of a microscopic alveolar adenoma coexisting with lung carcinoma: a case report and review of the literature. J Med Case Rep 2011;5:187. https://doi.org/10.1186/1752-1947-5-187
  4. Wang X, Li WQ, Yan HZ, et al. Alveolar adenoma combined with multifocal cysts: case report and literature review. J Int Med Res 2013;41:895-906. https://doi.org/10.1177/0300060513477304
  5. Kondo N, Torii I, Hashimoto M, et al. Alveolar adenoma of the lung: a case report. Ann Thorac Cardiovasc Surg 2011;17:71-73. https://doi.org/10.5761/atcs.cr.09.01504
  6. Fujimoto K, Muller NL, Sadohara J, Harada H, Hayashi A, Hayabuchi N. Alveolar adenoma of the lung: computed tomography and magnetic resonance imaging findings. J Thorac Imaging 2002;17:163-166. https://doi.org/10.1097/00005382-200204000-00011
  7. Burke LM, Rush WI, Khoor A, et al. Alveolar adenoma: a histochemical, immunohistochemical, and ultrastructural analysis of 17 cases. Hum Pathol 1999;30:158-167. https://doi.org/10.1016/S0046-8177(99)90270-8