DOI QR코드

DOI QR Code

Spinocerebellar Ataxia Type 2 with Only Clinical Feature of Memory Impairment: Case Report

기억장애가 유일한 임상양상으로 확인된 척수소뇌실조 2형 1예

  • 주재정 (보훈공단 중앙보훈병원 신경과) ;
  • 한상우 (보훈공단 중앙보훈병원 신경과) ;
  • 하상원 (보훈공단 중앙보훈병원 신경과) ;
  • 한정호 (보훈공단 중앙보훈병원 신경과) ;
  • 김두응 (보훈공단 중앙보훈병원 신경과) ;
  • 양영순 (보훈공단 중앙보훈병원 신경과)
  • Published : 2014.05.31

Abstract

Spinocerebellar ataxia (SCA) is one of a group of genetic disorders characterized by slowly progressive incoordination of gait and often associated with poor coordination of hands, speech, and eye movements. There are more than 35 different types of spinocerebellar ataxias, each caused by a different genetic mutation. Spinocerebellar ataxia type 2 (SCA2) is a subtype of type I autosomal dominant cerebellar ataxia (ADCA type I) characterized by truncal ataxia, dysarthria, slowed saccades and less commonly ophthalmoparesis and chorea. The age at onset varies from 3 to 79 years (mean 33). Usually, the first symptom of the disease is the gait ataxia, followed by the cerebellar dysarthria. Of late, other clinical manifestations of SCA2 are the cognitive dysfunctions, which include frontal executive impairment, verbal short-term memory deficits as well as reduction of attention and concentration. We report a 56-year old woman identified as spinocerebellar ataxia type 2 (SCA2) with only clinical feature of memory impairment.

Keywords