Quantitative CT Evaluation for Lung Volume and Density in Dogs

개에서 정량적 컴퓨터단층촬영을 이용한 폐용적과 폐밀도의 평가

  • Choi, Soo-Young (College of Veterinary Medicine.Research Institute of Veterinary Medicine, Chungnam National University) ;
  • Lee, In (College of Veterinary Medicine.Research Institute of Veterinary Medicine, Chungnam National University) ;
  • Jeong, Woo-Chang (College of Veterinary Medicine.Research Institute of Veterinary Medicine, Chungnam National University) ;
  • Heng, Hock Gan (College of Veterinary Medicine, Purdue University) ;
  • Lee, Young-Won (College of Veterinary Medicine.Research Institute of Veterinary Medicine, Chungnam National University) ;
  • Choi, Ho-Jung (College of Veterinary Medicine.Research Institute of Veterinary Medicine, Chungnam National University)
  • 최수영 (충남대학교 수의과대학.동물의과학연구소) ;
  • 이인 (충남대학교 수의과대학.동물의과학연구소) ;
  • 정우창 (충남대학교 수의과대학.동물의과학연구소) ;
  • ;
  • 이영원 (충남대학교 수의과대학.동물의과학연구소) ;
  • 최호정 (충남대학교 수의과대학.동물의과학연구소)
  • Accepted : 2014.10.07
  • Published : 2014.10.31

Abstract

In this study, we analyzed the computed tomography (CT) measurements of lung volume and density in dogs with relation to body weight, age, sex, and breed. The multi-detector CT examination of the thorax was performed on dogs without respiratory or cardiovascular diseases. Three-dimensional reconstruction of CT images facilitated measurement of lung volume and density. There was a statistical significant correlation between body weight and lung volume (p < 0.0001). Lung density significantly decreased with an increase in body weight (p = 0.0078). However, no correlation was seen between these lung parameters and either sex or age of the dogs. In conclusion, this study shows that body weight is an important factor to consider when interpreting total lung volume and density values measured by quantitative CT. We highlight the need for further study using quantitative CT in identifying the potential effects of sex, age, and disease status on these parameters.

컴퓨터단층촬영을 이용하여 개에서 폐용적과 폐밀도를 측정하였으며, 체중, 나이, 성별 및 품종에 따라 분석하였다. 데이터 수집을 위해 호흡기 질환이나 심혈관계질환이 없는 개에서 수행된 흉부 컴퓨터단층촬영 영상이 사용되었으며, 전체 폐용적과 밀도의 측정을 위해 컴퓨터단층촬영 영상의 재구성 기법을 이용하였다. 폐용적은 체중이 증가할수록 통계적으로 유의적인 증가를 보였다(p < 0.0001). 폐밀도는 체중이 증가함에 따라 유의적으로 감소하였다(p = 0.0078). 그러나, 폐용적과 밀도는 성별 또는 연령과 상관 관계를 보이지 않았다. 따라서, 정량적 컴퓨터단층촬영 검사로 전체 폐용적이나 폐밀도를 평가할 때 체중으로 인한 효과가 고려되어야 한다.

Keywords

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