Korean Journal of Medicinal Crop Science (한국약용작물학회지)

The Korean Society of Medicinal Crop Science (한국약용작물학회)
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Enhancement of Skin Immune Activities of Curcuma longa L. Leaf Extract by Ultra High Pressure Process

초고압 공정을 이용한 강황 잎 추출물의 피부 면역 활성 증진

  • Kim, Nam Young (Department of Medical Biomaterials Engineering, Kangwon National University) ;
  • Lee, Hyeon Yong (Department of Food Science and Engineering, Seowon University)
  • 김남영 (강원대학교 생물의소재공학과) ;
  • 이현용 (서원대학교 식품공학과)
  • Received : 2014.07.07
  • Accepted : 2014.09.02
  • Published : 2014.10.30
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Abstract

Curcuma longa L. leaf was extracted by water at $60^{\circ}C$ for 12 hours after being treatment of Ultra High Pressure under 500 MPa for 5-15 minute. The high pressure extraction for 15 minute (HPE15) was measured the highest extraction yield of 25.48% (w/w), compared to those from conventional extraction methods. The HPE15 showed the lowest cytotoxicity as 11.97% in adding $1.0mg/m{\ell}$ of concentration. Also, HPE15 was measured the highest inhibition of hyaluronidase as 44.48% in adding $1.0mg/m{\ell}$. In addition, The production of NO from macrophages was measured as $7.06{\mu}M$ in adding $1.0mg/m{\ell}$ of HPE15, which was lower than the those from others processes. Finally, HPE15 significantly reduced up to $649.44pg/m{\ell}$ of $ProstaglandinE_2$ production from UV-irradiation. These results suggest that the Curcuma longa Linne leaf extract from high pressure process might enhance the skin immune activities possibly by high elution of active components than other processes.

Keywords

References

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