Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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Rhinovirus Associated Severe Respiratory Failure in Immunocompetent Adult Patient

  • Kim, Kiwook (Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University College of Medicine) ;
  • Song, Yeon Han (Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University College of Medicine) ;
  • Park, Joo-Hyun (Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University College of Medicine) ;
  • Park, Hye Kyeong (Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University College of Medicine) ;
  • Kim, Su Young (Department of Radiology, Inje University Ilsan Paik Hospital, Inje University College of Medicine) ;
  • Jung, Hun (Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University College of Medicine) ;
  • Lee, Sung-Soon (Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University College of Medicine) ;
  • Koo, Hyeon-Kyoung (Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University College of Medicine)
  • Received : 2014.05.28
  • Accepted : 2014.05.30
  • Published : 2014.09.30
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Abstract

Rhinovirus infection is typically associated with the common cold and has rarely been reported as a cause of severe pneumonia in immunocompetent adults. A 55-year-old previous healthy woman, who consumed half a bottle of alcohol daily, presented with respiratory failure after one week of upper respiratory infection symptoms. Radiography revealed bilateral, diffuse ground glass opacity with patchy consolidation in the whole lung field; bronchoalveolar lavage fluid analysis indicated that rhinovirus was the causative organism. After five days of conservative support, the symptoms and radiographic findings began to improve. We report this rare case of rhinovirus pneumonia in an otherwise healthy host along with a review of references.

Keywords

References

  1. Hobson D, Schild GC. Virological studies in natural common colds in Sheffield in 1960. Br Med J 1960;2:1414-8. https://doi.org/10.1136/bmj.2.5210.1414
  2. Forsyth BR, Bloom HH, Johnson KM, Chanock RM. Patterns of illness in rhinovirus infections of military personnel. N Engl J Med 1963;269:602-6. https://doi.org/10.1056/NEJM196309192691203
  3. Nicholson KG, Kent J, Ireland DC. Respiratory viruses and exacerbations of asthma in adults. BMJ 1993;307:982-6. https://doi.org/10.1136/bmj.307.6910.982
  4. Calvo C, Garcia-Garcia ML, Blanco C, Pozo F, Flecha IC, Perez-Brena P. Role of rhinovirus in hospitalized infants with respiratory tract infections in Spain. Pediatr Infect Dis J 2007;26: 904-8. https://doi.org/10.1097/INF.0b013e31812e52e6
  5. Louie JK, Roy-Burman A, Guardia-Labar L, Boston EJ, Kiang D, Padilla T, et al. Rhinovirus associated with severe lower respiratory tract infections in children. Pediatr Infect Dis J 2009;28: 337-9. https://doi.org/10.1097/INF.0b013e31818ffc1b
  6. Hayden FG. Rhinovirus and the lower respiratory tract. Rev Med Virol 2004;14:17-31. https://doi.org/10.1002/rmv.406
  7. Hicks LA, Shepard CW, Britz PH, Erdman DD, Fischer M, Flannery BL, et al. Two outbreaks of severe respiratory disease in nursing homes associated with rhinovirus. J Am Geriatr Soc 2006;54:284-9. https://doi.org/10.1111/j.1532-5415.2005.00529.x
  8. Longtin J, Marchand-Austin A, Winter AL, Patel S, Eshaghi A, Jamieson F, et al. Rhinovirus outbreaks in long-term care facilities, Ontario, Canada. Emerg Infect Dis 2010;16:1463-5. https://doi.org/10.3201/eid1609.100476
  9. Jennings LC, Anderson TP, Beynon KA, Chua A, Laing RT, Werno AM, et al. Incidence and characteristics of viral community-acquired pneumonia in adults. Thorax 2008;63:42-8. https://doi.org/10.1136/thx.2006.075077
  10. Johnstone J, Majumdar SR, Fox JD, Marrie TJ. Viral infection in adults hospitalized with community-acquired pneumonia: prevalence, pathogens, and presentation. Chest 2008;134: 1141-8. https://doi.org/10.1378/chest.08-0888
  11. Ruuskanen O, Lahti E, Jennings LC, Murdoch DR. Viral pneumonia. Lancet 2011;377:1264-75. https://doi.org/10.1016/S0140-6736(10)61459-6
  12. Choi SH, Hong SB, Ko GB, Lee Y, Park HJ, Park SY, et al. Viral infection in patients with severe pneumonia requiring intensive care unit admission. Am J Respir Crit Care Med 2012;186: 325-32. https://doi.org/10.1164/rccm.201112-2240OC
  13. Joshi PC, Guidot DM. The alcoholic lung: epidemiology, pathophysiology, and potential therapies. Am J Physiol Lung Cell Mol Physiol 2007;292:L813-23. https://doi.org/10.1152/ajplung.00348.2006
  14. Polikandriotis JA, Rupnow HL, Elms SC, Clempus RE, Campbell DJ, Sutliff RL, et al. Chronic ethanol ingestion increases superoxide production and NADPH oxidase expression in the lung. Am J Respir Cell Mol Biol 2006;34:314-9. https://doi.org/10.1165/rcmb.2005-0320OC
  15. Pang M, Bala S, Kodys K, Catalano D, Szabo G. Inhibition of TLR8- and TLR4-induced Type I IFN induction by alcohol is different from its effects on inflammatory cytokine production in monocytes. BMC Immunol 2011;12:55. https://doi.org/10.1186/1471-2172-12-55

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