참고문헌
- Aybar, M. J., Snchez Riera A. N., Grau, A. and Snchez, S. S. (2001) Hypoglycemic effect of the water extract of Smallanthus sonchifolius (yacon) leaves in normal and diabetic rats. J. Ethnopharm. 74: 125-132. https://doi.org/10.1016/S0378-8741(00)00351-2
- Habib, N. C., Honor, S. M., Genta, S. B. and Snchez, S. S. (2011) Hypolipidemic effect of Smallanthus sonchifolius (yacon) roots on diabetic rats. biochemical approach. Chem. Biol. Interact. 194: 31-39. https://doi.org/10.1016/j.cbi.2011.08.009
- Yan, X., Suzuki, M., Ohnishi-Kameyama, M., Sada, Y., Nakanishi, T. and Nagata, T. (1999) Extraction and identification of antioxidants in roots of yacon (Smallanthus sonchifolius). J. Agric. Food Chem. 47: 4711-4713. https://doi.org/10.1021/jf981305o
- Simonovska, B., Vovk, I., Andrenek, S., Valentov, K. and Ulrichov, J. (2003) Investigation of phenolic acids in yacon (Smallanthus sonchifolius) leaves and tubers. J. Chromatography A, 1016: 89-98. https://doi.org/10.1016/S0021-9673(03)01183-X
- Goto, K., Fukai, K., Hikida, J., Nanjo, F. and Hara, Y. (1995) Isolation and structural analysis of oligosaccharides from yacon (Polymnia sonchifolia). Biosci. Biotechnol. Biochem. 59: 2346-2347. https://doi.org/10.1271/bbb.59.2346
- Park. J. S., Hwang, S. Y. and Han, K. (2009) The spermatogenic effect of 50% ethanol extracts of Yacon in healthy volunteers. Yakhak Haeji, 53: 250-258.
- Hiipakka, R. A., Zhang, H. Z., Dai, W., Dai, Q. and Liao, S. (2002) Structure-activity relationships for inhibition of human 5alpha-reductases by polyphenols. Biochem. Pharmacol. 63: 1165-1176. https://doi.org/10.1016/S0006-2952(02)00848-1
-
Sun, J., Xiang, H., Yang, L. L. and Chen, J. B. (2011) A review on steroidal 5
$\alpha$ -reductase inhibitors for treatment of benign prostatic hyperplasia. Curr. Med. Chem. 18: 3576-3589. https://doi.org/10.2174/092986711796642517 -
Traish, A, M., Hassani, J., Guay, A. T., Zitzmann, M. and Hansen, M. L. (2011) Adverse side effects of 5
$\alpha$ -reductase inhibitors therapy: Persistent diminished libido and erectile dysfunction and depression in a subset of patients. J. Sexual Medicine, 8: 872-884. https://doi.org/10.1111/j.1743-6109.2010.02157.x -
Pumthong, G., Asawanonda, P., Varothai, S., Jariyasethavong, V., Triwongwaranat, D., Suthipinittharm, P., Ingkaninan, K., Leelapornpisit, P. and Waranuch, N. (2012) Curcuma aeruginosa, a novel botanically derived 5
$\alpha$ -reductase inhibitor in the treatment of male-pattern baldness: a multicenter, randomized, double-blind, placebo-controlled study. J. Dermatolog. Treat. 23: 385-392. https://doi.org/10.3109/09546634.2011.568470 - Bach, D., Schmitt, M. and Ebeling, L. (1997) Phytopharmaceutical and synthetic agents in the treatment of benign prostatic hyperplasia (BPH). Phytomedicine 3: 309-313. https://doi.org/10.1016/S0944-7113(97)80001-3
- Park, W. S., Son, E. D., Nam, G. W., Kim, S. H., Noh, M. S., Lee, B. G., Jang, I. S., Kim, S. E., Lee, J. J. and Lee, C. H. (2003) Torilin from Torilis japonica, as a new inhibitor of testosterone 5 alpha-reductase. Planta Med. 69: 459-461. https://doi.org/10.1055/s-2003-39717
- Chen, Q. X., Miao, J. K., Li, C., Li, X. W., Wu, X. M. and Zhang, X. P. (2013) Anticonvulsant activity of acute and chronic treatment with a-asarone from Acorus gramineus in seizure models. Biol. Pharm. Bull. 36: 23-30.
- Hwang, E. I., Lee, S. K., So, S. H., Koo, B. S., Han, G. and Kim, N. M. (2007) Isolation and development of quantitative determination of Torilin from the Torilis Fructus. Kor. J. Pharmacogn. 38: 321-326.
- Yang, H., Yuan, B., Chen, H. and Li, F. (2004) HPLC determination and pharmacokinetics of chlorogenic acid in rabbit plasma after an oral dose of Flos Lonicerae extract. J. Chromatogr. Sci. 42: 173-176. https://doi.org/10.1093/chromsci/42.4.173
- Wen, J., Kang, L., Liu, H., Xiao, Y., Zhang, X. and Chen, Y. (2012) A validated UV-HPLC method for determination of chlorogenic acid in Lepidogrammitis drymoglossoides (Baker) Ching, Polypodiaceae. Pharmacognosy Res. 4: 148-153. https://doi.org/10.4103/0974-8490.99076
-
Ma, W. C., Zhang, Q., Li, H., Larregieu, C. A., Zhang, N., Chu, T., Jin, H. and Mao, S. J. (2013) Development of intravenous lipid emulsion of
$\alpha$ -asarone with significantly improved safety and enhanced efficacy. Int. J. Pharm. 42: 21-30. -
Wu, J. P. and He, L. Y.(2007) RP-HPLC determination of content of
$\alpha$ -asarone and related substances. J. Pharma. Anal. 3: 364-366. -
Mythili, A. M. N., Immanuel, S. C., Rajasekharan, P. E., Rajasekharan, C., Tharachand, C., Rao, V. K. and Munirajappa, H. (2013) HPLC profiling of
$\beta$ -asarone content and cytogenetic studies of medicinally important Indian Acorus calamus l. Int. J. pharm. Sci. 22: 73-78. - Shin, I. S., Lee, M. Y., Ha, H. K., Seo, C. S. and Shin, H. K. (2012) Inhibitory effect of Yukmijihwang-tang, a traditional herbal formula against testosterone-induced benign prostatic hyperplagia in rats. BMC Complement. & Altern. Med. 12: 48-54. https://doi.org/10.1186/1472-6882-12-48
- Koutsari, C., Ali, A. H., Nair, K. S., Rizza, R. A., O'Brien. P., Khosla, S. and Jensen, M. D. (2009) Fatty acid metabolism in the elderly: effects of dehydroepiandrosterone and testosterone replacement in hormonally deficient men and women. J. Clin. Endocrinol. Metab. 94: 3414-3423. https://doi.org/10.1210/jc.2009-0165