Journal of Korean Neurosurgical Society

  • 제55권5호
  • /
  • Pages.244-247
  • /
  • 2014
  • /
  • 2005-3711(pISSN)
  • /
  • 1598-7876(eISSN)
대한신경외과학회 (The Korean Neurosurgical Society)
권호 표지
DOI QR코드

DOI QR Code

Microanatomy and Histological Features of Central Myelin in the Root Exit Zone of Facial Nerve

  • Yee, Gi-Taek (Department of Neurosurgery, Gil Medical Center, Gachon University) ;
  • Yoo, Chan-Jong (Department of Neurosurgery, Gil Medical Center, Gachon University) ;
  • Han, Seong-Rok (Deparment of Neurosurgery, Ilsan Paik Hospital, College of Medicine, Inje University) ;
  • Choi, Chan-Young (Deparment of Neurosurgery, Ilsan Paik Hospital, College of Medicine, Inje University)
  • 투고 : 2013.07.23
  • 심사 : 2014.05.15
  • 발행 : 2014.05.28
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Objective : The aim of this study was to evaluate the microanatomy and histological features of the central myelin in the root exit zone of facial nerve. Methods : Forty facial nerves with brain stem were obtained from 20 formalin fixed cadavers. Among them 17 facial nerves were ruined during preparation and 23 root entry zone (REZ) of facial nerves could be examined. The length of medial REZ, from detach point of facial nerve at the brain stem to transitional area, and the thickness of glial membrane of central myelin was measured. We cut brain stem along the facial nerve and made a tissue block of facial nerve REZ. Each tissue block was embedded with paraffin and serially sectioned. Slices were stained with hematoxylin and eosin (H&E), periodic acid-Schiff, and glial fibrillary acid protein. Microscopy was used to measure the extent of central myelin and thickness of outer glial membrane of central myelin. Thickness of glial membrane was examined at two different points, the thickest area of proximal and distal REZ. Results : Special stain with PAS and GFAP could be differentiated the central and peripheral myelin of facial nerve. The length of medial REZ was mean 2.6 mm (1.6-3.5 mm). The glial limiting membrane of brain stem is continued to the end of central myelin. We called it glial sheath of REZ. The thickness of glial sheath was mean $66.5{\mu}m(40-110{\mu}m$) at proximal REZ and $7.4{\mu}m(5-10{\mu}m$) at distal REZ. Conclusion : Medial REZ of facial nerve is mean 2.6 mm in length and covered by glial sheath continued from glial limiting membrane of brain stem. Glial sheath of central myelin tends to become thin toward transitional zone.

키워드

참고문헌

  1. Adams CB : Microvascular compression : an alternative view and hypothesis. J Neurosurg 70 : 1-12, 1989 https://doi.org/10.3171/jns.1989.70.1.0001
  2. De Ridder D, Moller A, Verlooy J, Cornelissen M, De Ridder L : Is the root entry/exit zone important in microvascular compression syndromes? Neurosurgery 51 : 427-433; discussion 433-434, 2002 https://doi.org/10.1227/00006123-200208000-00023
  3. Gardner WJ : Concerning the mechanism of trigeminal neuralgia and hemifacial spasm. J Neurosurg 19 : 947-958, 1962 https://doi.org/10.3171/jns.1962.19.11.0947
  4. Gardner WJ : Cross talk--the paradoxical transmission of a nerve impulse. Arch Neurol 14 : 149-156, 1966 https://doi.org/10.1001/archneur.1966.00470080033005
  5. Henschen F : Zur Histologie und Pathogenese der Kleinhirnbruckenwinkeltumoren. Arch Psychiat Nervenkr 56 : 21-122, 1915
  6. Jannetta PJ : The cause of hemifacial spasm : definitive microsurgical treatment at the brainstem in 31 patients. Trans Sect Otolaryngol Am Acad Ophthalmol Otolaryngol 80 (3 Pt 1) : 319-322, 1975
  7. Jannetta PJ, Abbasy M, Maroon JC, Ramos FM, Albin MS : Etiology and definitive microsurgical treatment of hemifacial spasm. Operative techniques and results in 47 patients. J Neurosurg 47 : 321-328, 1977 https://doi.org/10.3171/jns.1977.47.3.0321
  8. McFarland DE, Friede RL : Number of fibres per sheath cell and internodal length in cat cranial nerves. J Anat 109 (Pt 1) : 169-176, 1971
  9. Moller AR, Jannetta PJ : On the origin of synkinesis in hemifacial spasm : results of intracranial recordings. J Neurosurg 61 : 569-576, 1984 https://doi.org/10.3171/jns.1984.61.3.0569
  10. Nakazawa E, Ishikawa H : Ultrastructural observations of astrocyte end-feet in the rat central nervous system. J Neurocytol 27 : 431-440, 1998 https://doi.org/10.1023/A:1006936527746
  11. Peker S, Kurtkaya O, Uzun I, Pamir MN : Microanatomy of the central myelin-peripheral myelin transition zone of the trigeminal nerve. Neurosurgery 59 : 354-359; discussion 354-359, 2006 https://doi.org/10.1227/01.NEU.0000223501.27220.69
  12. Skinner HA : Some histologic features of the cranial nerves. Arch Neurol Psychiatry 25 : 356-372, 1931 https://doi.org/10.1001/archneurpsyc.1931.02230020144008
  13. Tomii M, Onoue H, Yasue M, Tokudome S, Abe T : Microscopic measurement of the facial nerve root exit zone from central glial myelin to peripheral Schwann cell myelin. J Neurosurg 99 : 121-124, 2003 https://doi.org/10.3171/jns.2003.99.1.0121

피인용 문헌

  1. Surgical Treatment of Hemifacial Spasm Caused by the Compression of Internal Auditory Canal of Facial Nerve vol.28, pp.6, 2014, https://doi.org/10.1097/scs.0000000000003872