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이상성 경과를 보이고 정맥면역글로불린 치료 후 호전된 일본뇌염

Japanese-B Viral Encephalitis with a Biphasic Illness Pattern and Recovery after Intravenous Immunoglobulin Therapy

  • 이병찬 (계명대학교 의과대학 신경과학교실) ;
  • 전지예 (계명대학교 의과대학 신경과학교실) ;
  • 문혜진 (계명대학교 의과대학 신경과학교실) ;
  • 임정근 (계명대학교 의과대학 신경과학교실) ;
  • 조용원 (계명대학교 의과대학 신경과학교실)
  • Lee, Byung-Chan (Department of Neurology, Keimyung University School of Medicine) ;
  • Jeon, Ji Ye (Department of Neurology, Keimyung University School of Medicine) ;
  • Moon, Hye-Jin (Department of Neurology, Keimyung University School of Medicine) ;
  • Lim, Jeong Geun (Department of Neurology, Keimyung University School of Medicine) ;
  • Cho, Yong Won (Department of Neurology, Keimyung University School of Medicine)
  • 투고 : 2013.11.13
  • 심사 : 2014.06.09
  • 발행 : 2014.06.30

초록

Japanese-B viral encephalitis (JE) usually has a monophasic illness pattern. A 45-year-old woman in an altered mentality had improved over 1 month. About 1 week after the initial improvement, the patient became comatose with aggravated EEG and MRI findings. Assays of cerebrospinal fluid and serum were positive for the IgM antibody to Japanese-B virus. After intravenous immunoglobulin (IVIG) infusion, the patient recovered. We report a patient with JE who showed a biphasic illness pattern and recovered after IVIG therapy.

키워드

참고문헌

  1. Misra UK, Kalita J. Prognosis of Japanese encephalitis patients with dystonia compared to those with parkinsonian features only. Postgrad Med J 2002;78:238-241. https://doi.org/10.1136/pmj.78.918.238
  2. Dickerson RB, Newton JR, Hansen JE. Diagnosis and immediate prognosis of Japanese B encephalitis; observations based on more than 200 patients with detailed analysis of 65 serologically confirmed cases. Am J Med 1952;12:277-288. https://doi.org/10.1016/0002-9343(52)90356-2
  3. Pradhan S, Gupta RK, Singh MB, Mathur A. Biphasic illness pattern due to early relapse in Japanese-B virus encephalitis. J Neurol Sci 2001;183:13-18. https://doi.org/10.1016/S0022-510X(00)00453-6
  4. Zimmerman HM. The pathology of Japanese B encephalitis. Am J Pathol 1946;22:965-991.
  5. Lai CC, Liu WL, Lin SC, Hsiao YC, Ding LW. Diagnostic MR images of Japanese encephalitis. J Emerg Med 2008;35:305-307. https://doi.org/10.1016/j.jemermed.2007.02.042
  6. Mathur A, Arora KL, Chaturvedi UC. Host defence mechanisms against Japanese encephalitis virus infection in mice. J Gen Virol 1983;64:805-811. https://doi.org/10.1099/0022-1317-64-4-805
  7. Sharma S, Mathur A, Prakash V, Kulshreshtha R, Kumar R, Chaturvedi UC. Japanese encephalitis virus latency in peripheral blood lymphocytes and recurrence of infection in children. Clin Exp Immunol 1991;85:85-89.
  8. Hoke CH, Jr., Vaughn DW, Nisalak A, Intralaw P, Poolsuppasit S, Jongsawas V, et al. Effect of high-dose dexamethasone on the outcome of acute encephalitis due to Japanese encephalitis virus. J Infect Dis 1992;165:631-637. https://doi.org/10.1093/infdis/165.4.631
  9. Caramello P, Canta F, Balbiano R, Lipani F, Ariaudo S, De Agostini M, et al. Role of intravenous immunoglobulin administration in Japanese encephalitis. Clin Infect Dis 2006;43:1620-1621. https://doi.org/10.1086/509644

피인용 문헌

  1. Effectiveness of Intravenous Immunoglobulin Therapy for Pediatric Viral Encephalitis vol.28, pp.4, 2014, https://doi.org/10.26815/acn.2020.00164