Transactions of the Korean Society of Mechanical Engineers B (대한기계학회논문집B)

The Korean Society of Mechanical Engineers (대한기계학회)
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Three-Dimensional Printed 3D Structure for Tissue Engineering

3 차원 프린팅 기술로 제작된 조직공학용 3 차원 구조체

  • 박정훈 (포항공과대학교 기계공학과) ;
  • 장진아 (포항공과대학교 융합생명공학부) ;
  • 조동우 (포항공과대학교 기계공학과)
  • Received : 2014.03.11
  • Accepted : 2014.07.29
  • Published : 2014.10.01
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Abstract

One of the main issues in tissue engineering has been the development of a three-dimensional (3D) structure, which is a temporary template that provides the structural support and microenvironment necessary for cell growth and differentiation into the target tissue. In tissue engineering, various biomaterials and their processing techniques have been applied for the fabrication of 3D structures. In particular, 3D printing technology enables the fabrication of a complex inner/outer architecture using a computer-aided design and manufacturing (CAD/CAM) system, and it has been widely applied to the fabrication of 3D structures for tissue engineering. Novel cell/organ printing techniques based on 3D printing have also been developed for the fabrication of a biomimetic structure with various cells and biomaterials. This paper presents a comprehensive review of the functional scaffold and cell-printed structures based on 3D printing technology and the application of this technology to various kinds of tissues regeneration.

조직공학 분야에서의 3 차원 구조체는 세포의 성장과 분화를 유도하기 위한 미세 환경을 제공하고, 재생하고자 하는 조직의 형태를 유지할 수 있도록 지탱해 주는 역할을 수행한다. 현재까지 다양한 생체재료 및 이의 가공 기법들이 이러한 3 차원 구조체를 제작하는데 적용되고 있다. 특히, 3 차원 프린팅 기술은 다양한 재료를 이용하여 원하는 외부 형상과 내부 구조를 제작할 수 있기 때문에 오늘날 조직공학 분야에 많이 이용되고 있고, 이 기술을 통해 새로운 조직공학적 접근 방법도 시도되고 있다. 본 논문에서는, 현재 조직공학 분야에 적용되고 있는 3 차원 프린팅 기술과, 이를 통해 제작된 기능성 인공지지체 및 세포 프린팅 구조체, 그리고 이의 다양한 조직공학적 적용에 대해서 서술하고자 한다.

Keywords

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