대한치과교정학회지 (The korean journal of orthodontics)

  • 제44권5호
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  • Pages.246-253
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  • 2014
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  • 2234-7518(pISSN)
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  • 2005-372X(eISSN)
대한치과교정학회 (The Korean Association Of Orthodontists)
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Enhanced compatibility and initial stability of Ti6Al4V alloy orthodontic miniscrews subjected to anodization, cyclic precalcification, and heat treatment

  • Oh, Eun-Ju (Sun Dental Hospital) ;
  • Nguyen, Thuy-Duong T. (Department of Dental Biomaterials and Institute of Oral Bioscience, Brain Korea 21 Project, School of Dentistry, Chonbuk National University) ;
  • Lee, Seung-Youp (Department of Orthodontics, School of Dentistry, Chonbuk National University) ;
  • Jeon, Young-Mi (Department of Orthodontics, School of Dentistry, Chonbuk National University) ;
  • Bae, Tae-Sung (Department of Dental Biomaterials and Institute of Oral Bioscience, Brain Korea 21 Project, School of Dentistry, Chonbuk National University) ;
  • Kim, Jong-Gee (Department of Orthodontics, School of Dentistry, Chonbuk National University)
  • 투고 : 2013.12.27
  • 심사 : 2014.03.25
  • 발행 : 2014.09.25
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초록

Objective: To evaluate the bioactivity, and the biomechanical and bone-regenerative properties of Ti6Al4V miniscrews subjected to anodization, cyclic precalcification, and heat treatment (APH treatment) and their potential clinical use. Methods: The surfaces of Ti6Al4V alloys were modified by APH treatment. Bioactivity was assessed after immersion in simulated body fluid for 3 days. The hydrophilicity and the roughness of APH-treated surfaces were compared with those of untreated (UT) and anodized and heat-treated (AH) samples. For in vivo tests, 32 miniscrews (16 UT and 16 APH) were inserted into 16 Wistar rats, one UT and one APH-treated miniscrew in either tibia. The miniscrews were extracted after 3 and 6 weeks and their osseointegration (n = 8 for each time point and group) was investigated by surface and histological analyses and removal torque measurements. Results: APH treatment formed a dense surface array of nanotubular TiO2 layer covered with a compact apatite-like film. APH-treated samples showed better bioactivity and biocompatibility compared with UT and AH samples. In vivo, APH-treated miniscrews showed higher removal torque and bone-to-implant contact than did UT miniscrews, after both 3 and 6 weeks (p < 0.05). Also, early deposition of densely mineralized bone around APH-treated miniscrews was observed, implying good bonding to the treated surface. Conclusions: APH treatment enhanced the bioactivity, and the biomechanical and bone regenerative properties of the Ti6Al4V alloy miniscrews. The enhanced initial stability afforded should be valuable in orthodontic applications.

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참고문헌

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