Journal of Acupuncture Research

Korean Acupuncture & Moxibustion Medicine Society (대한침구의학회)
권호 표지
DOI QR코드

DOI QR Code

A Clinical Case Study on the Long Term Respiration Management of Amyotrophic Lateral Sclerosis Patient with Respiratory Failure

호흡부전을 동반한 근위축성 측삭 경화증 환자의 장기적 호흡관리 1례

  • Lee, Jong Cheol (Department of Acupuncture & Moxibustion Medicine, Gwangju Korean Medical Hospital, Wonkwang University) ;
  • Jeong, Ho Hyun (Department of Acupuncture & Moxibustion Medicine, Gwangju Korean Medical Hospital, Wonkwang University) ;
  • Cha, Eun Hye (Department of Acupuncture & Moxibustion Medicine, Gwangju Korean Medical Hospital, Wonkwang University) ;
  • Park, Man Yong (Department of Acupuncture & Moxibustion Medicine, Gwangju Korean Medical Hospital, Wonkwang University) ;
  • Kim, Tae Ho (Department of Acupuncture & Moxibustion Medicine, Bucheon Jaseng Hospital of Korean Medicine) ;
  • Song, Bong Keun (Department of Internal Medicine, Gwangju Korean Medical Hospital, Wonkwang University) ;
  • Son, Il Hong (Department of Neurology, Sanbon Hospital, Wonkwang University) ;
  • Kim, Sung Chul (Department of Acupuncture & Moxibustion Medicine, Gwangju Korean Medical Hospital, Wonkwang University)
  • 이종철 (원광대학교 부속광주한방병원 침구의학과) ;
  • 정호현 (원광대학교 부속광주한방병원 침구의학과) ;
  • 차은혜 (원광대학교 부속광주한방병원 침구의학과) ;
  • 박만용 (원광대학교 부속광주한방병원 침구의학과) ;
  • 김태호 (부천자생한방병원 침구의학과) ;
  • 송봉근 (원광대학교 부속광주한방병원 내과) ;
  • 손일홍 (원광대학교 부속산본병원 신경과) ;
  • 김성철 (원광대학교 부속광주한방병원 침구의학과)
  • Received : 2014.08.11
  • Accepted : 2014.08.28
  • Published : 2014.09.20
Download PDF
⟨ Previous Next ⟩

Abstract

Objectives : Amyotrophic lateral sclerosis(ALS) is a progressive neurodegenerative disorder characterized by a selective death of motor neuron, leading to respiratory insufficiency. The purpose of this study was to assess the long term respiratory management of ALS patient with respiratory failure. Methods : One ALS patient applying a non-invasive BIPAP ventilator as well as Korean medical treatment such as acupuncture, pharmacopuncture and herbal medicine was measured on $SpO_2$, $EtCO_2$, Vte(expiratorytidalvolume) for 2 years 7 months. Results : The $SpO_2$, $EtCO_2$ of ALS patient were maintained in the normal range for 2 years 7 months. The Vte of ALS patient also wasn't worse in this study. Conclusions : In this study, the long term respiration management, combined administration of Korean medical treatment and non-invasive BIPAP ventilator, could be effective in ALS patient with respiratory failure.

Keywords

References

  1. Paul H Gordon. Amyotrophic lateral sclerosis: an update for 2013 clinical features, pathophysiology, management and therapeutic trials. Aging and Disease. 2013 ; 4(5) : 295-310. https://doi.org/10.14336/AD.2013.0400295
  2. Kim SH. Diagnosis and therapeutic strategies of amyotrophic lateral sclerosis. Hanyang Medical Reviews. 2006 ; 26(1) : 45-51.
  3. Haverkamp LJ, Appel V, Appel SH. Natural history of amyotrophic lateral sclerosis in a database population. Validation of a scoring system and a model for survival prediction Brain. 1995 ; 118(3) : 707-19. https://doi.org/10.1093/brain/118.3.707
  4. Caroscio JT, Mulvihill MN, Sterling R, Abrams B. Amyotrophic lateral sclerosis, its natural history. Neurol Clin. 1987 ; 5(1) : 1-9.
  5. Mulder DW. Motor neuron disease. In: Dyck PJ, Thomas PK, Lambert EH, Bunge R eds. Peripheral neuropathy, ed 2, Vol. 2. Philadelphia PA : WB Saunders. 1984 : 1525-36.
  6. Radunovic A, Annane D, Rafiq MK, Mustfa N, Mechanical ventilation for amyotrophic lateral sclerosis/motor neuron disease. The Cochrane Database of Systemic Reviews. 2013 ; published online 28 : 3.
  7. Gordon PH, Corcia P, Lacomblez L et al. Defining survival as an outcome measure in amyotrophic lateral sclerosis. Arch Neurol. 2009 ; 66(6) : 758-61.
  8. Lacomblez L, Bensimon G, Leigh PN, Guillet P, Meininger V. Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis/Riluzole Study Group II. Lancet, 1996 ; 347(9013) : 1425-31. https://doi.org/10.1016/S0140-6736(96)91680-3
  9. Bensimon G, Lacomblez L, Meininger V. A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group. N Engl J Med. 1994 ; 330(9) : 585-91. https://doi.org/10.1056/NEJM199403033300901
  10. Miller RG, Mitchell JD, Moore DH. Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease(MND). Cochrane Database Syst Rev. 2012 ; published online 14 : 3.
  11. Gordon PH, Mitsumoto H. Chapter 20 symptomatic therapy and palliative aspects of clinical care. Handb Clin Neurol, Netherlands : North-Holland Pub Co. 2008 ; 389-424.
  12. Heckmatt JZ, Loh L, Dubowitz V. Night-time nasal ventilation in neuromuscular disease. Lancet. 1990 ; 335(8689) : 579-82. https://doi.org/10.1016/0140-6736(90)90357-B
  13. Bourke SC, Tomlinson M, Williams TL, Bullock RE, Shaw PJ, Gibson GJ. Effects of non-invasive ventilation on survival and quality of life in patients with amyotrophic lateral sclerosis: a randomised controlled trial. Lancet Neurol. 2006 ; 5(2) : 140-7. https://doi.org/10.1016/S1474-4422(05)70326-4
  14. Lee S, Kim S. The effects of Sa-am acupuncture treatment on respiratory phsiology parameters in amyotrophic lateral sclerosis patients: a pilot study. Evid Based Complement alternat Med. 2013 ; published online 11 : 9.
  15. Tandan R, Bradley WG, Amyotrophic lateral sclerosis: part 1. clinical features, pathology, and ethical issues in management. Ann Neurol. 1985 ; 18(3) : 271-80. https://doi.org/10.1002/ana.410180302
  16. Rowland LP, Shneider NA. Amyotrophic lateral sclerosis. N Engl J Med. 2001 ; 344(22) : 1688-700. https://doi.org/10.1056/NEJM200105313442207
  17. Del Aguila MA, Longstreth WT Jr, McGuire V, Koepsell TD, van Belle G. Prognosis in amyotrophic lateral sclerosis: a population-based study. Neurology. 2003 ; 60(5): 813-19. https://doi.org/10.1212/01.WNL.0000049472.47709.3B
  18. Miller RG, Jackson CE, Kasarskis EJ et al. Practice parameter update: the care of the patient with amyotrophic lateral sclerosis: drug, nutritional, and respiratory therapies(an evidencebased review): report of the quality standards subcommittee of the American Academy of Neurology. Neurology. 2009 ; 73(24) : 1218-26. https://doi.org/10.1212/WNL.0b013e3181bc0141
  19. Morgan RK, McNally S, Alexander M, Conroy R, Hardiman O, Costello RW. Use of sniff nasalinspiratory force to predict survival in amyotrophic lateral sclerosis. Am J Respir Crit Care Med. 2005 ; 171(3) : 269-74. https://doi.org/10.1164/rccm.200403-314OC
  20. Baumann F, Henderson RD, Morrison SC et al. Use of respiratory function tests to predict survival in amyotrophic lateral sclerosis. Amyotroph lateral sclera. 2010 ; 1-2) : 194-202.
  21. Newsom-Davis IC, Lyall RA, Leigh PN, Moxham J, Goldstein LH. The effect of non-invasive positive pressure ventilation(NIPPV) on cognitive function in amyotrophic lateral sclerosis(ALS): a prospective study. J Neurol Neurosurg Psychiatry. 2001 ; 71(4) : 482-7. https://doi.org/10.1136/jnnp.71.4.482
  22. Heiman-Patterson TD, Miller RG. NIPPV: a treatment for ALS whose time has come. Neurology. 2006 ; 67(5) : 736-7. https://doi.org/10.1212/01.wnl.0000238978.69141.57
  23. Korean acupuncture & Moxibustion Medicine Society Textbook Compailation Commitee. Korean acupuncture & moxibustion medicine. Ha volume. Gyeonggi : Jipmoondang. 2008 : 197-200.
  24. Heo J. Donguibogam. Seoul : Yeogang Publishing Company. 1994 : 1060-1, 1102-3.
  25. Kim DH. Illustrations Kyokam Sa-am Do-in acupuncture. Busan : Sogang. 2002 : 475-80.
  26. Wade OL. Movements of the thoracic cage and diaphragm in respiration. The Journal of physiology. 1954 ; 124(2) : 193. https://doi.org/10.1113/jphysiol.1954.sp005099
  27. Kim E Barrett, Susan M Barman, Scott Boitano, Heddwen Brooks. "35. Pulmonary Function". Ganong's review of medical physiology, 23rd edition. USA : McGraw-Hill Companies, Incorporated. 2009. Cite uses deprecated parameters(587-638 help).
  28. Campbell EJ. M. The role of the scalene and sternomastoid muscles in breathing in normal subjects. An electromyographic study. Journal of Anatomy. 1955 ; 89(3) : 378-86.
  29. Netter FH. Atlas of human anatomy 3rd ed. Icon learning systems. Teterboro. New Jersey : Icon learning systems. 2003 : 191.
  30. Raper AJ, Thompson WT, Shapiro W, Patterson JL. Scalene and sternomastoid muscle function. Journal of Applied Physiology. 1966 ; 21(2) : 497-502.
  31. De Troyer A. Respiratory muscle function. In: Gibson J, Geddes DM, Costabel U et al ed. Respiratory medicine. London : Saunders. 2003 : 119-29.
  32. Rakhit R, Cunningham P, Furtos-Matei A et al. Oxidation-induced misfolding and aggregation of superoxide dismutase and its implications for amyotrophic lateral sclerosis. J Biol Chem. 2002 ; 277(49) : 47551-6. https://doi.org/10.1074/jbc.M207356200
  33. Dal Canto MC, Gurney ME. Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu, Zn SOD, and in mice overexpressing wild type human SOD: a model of familial amyotrophic lateral sclerosis (FALS). Brain Res. 1995 ; 676(1) : 25-40. https://doi.org/10.1016/0006-8993(95)00063-V
  34. Nguyen MD, Lariviere RC, Julien JP. Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions. Neuron. 2001 ; 30(1) : 135-47. https://doi.org/10.1016/S0896-6273(01)00268-9
  35. Cai MuDan, Choi SM, Song BK, Son IH, Kim SC, Yang EJ. Scolopendra subspinipes mutilans attenuates neuroinflammation in symptomatic hSOD1G93A mice. Journal of Neuroinflammation 2013 : 10(1) : 131. https://doi.org/10.1186/1742-2094-10-131
  36. Lee SH, Choi SM, Yang EJ. Melittin ameliorates the inflammation of organs in an amyotrophic lateral sclerosis animal model. Exp Neurobiol. 2014 Mar ; 23(1) : 86-92. https://doi.org/10.5607/en.2014.23.1.86
  37. Gammage GW, Banner MJ, Blanch PB, et al. Ventilator displayed tidal volume: what you see may not be what you get. Crit Care Med. 1988 ; 16(4) : 454.

Cited by

  1. 근위축성 측삭경화증의 한방치료에 관한 문헌적 고찰연구 vol.32, pp.4, 2015, https://doi.org/10.13045/acupunct.2015068
  2. Traditional East Asian Herbal Medicine for Amyotrophic Lateral Sclerosis: A Scoping Review vol.2021, pp.None, 2014, https://doi.org/10.1155/2021/5674142