Restorative Dentistry and Endodontics

  • 제39권3호
  • /
  • Pages.230-234
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  • 2014
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  • 2234-7658(pISSN)
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  • 2234-7666(eISSN)
대한치과보존학회 (The Korean Academy of Conservative Dentistry)
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The use of platelet rich plasma in the treatment of immature tooth with periapical lesion: a case report

  • Polat, Gunseli Guven (Department of Pediatric Dentistry, Center for Dental Sciences, Gulhane Medical Academy) ;
  • Yildirim, Ceren (Department of Pediatric Dentistry, Center for Dental Sciences, Gulhane Medical Academy) ;
  • Akgun, Ozlem Marti (Department of Pediatric Dentistry, Center for Dental Sciences, Gulhane Medical Academy) ;
  • Altun, Ceyhan (Department of Pediatric Dentistry, Center for Dental Sciences, Gulhane Medical Academy) ;
  • Dincer, Didem (Department of Dermatology, Gulhane Medical Academy) ;
  • Ozkan, Cansel Kose (Center for Pharmaceutical Sciences, Gulhane Medical Academy)
  • 투고 : 2014.01.22
  • 심사 : 2014.04.23
  • 발행 : 2014.08.30
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초록

This study describes the treatment of an immature permanent tooth with periapical lesion which was treated with regenerative approach using platelet rich plasma (PRP). The root canal of immature human permanent tooth with periapical lesion was gently debrided of necrotic tissue and disinfected with 2.5% NaOCl, and then medicated with triple antibiotic paste comprised of ciprofloxacin, metronidazole, and tetracycline. When the tooth was asymptomatic, PRP and mineral trioxide aggregate (MTA) were placed into the root canal. Six months after PRP treatment, radiographical examination revealed resolution of the radiolucency and progressive thickening of the root wall and apical closure. Our findings suggest that PRP can be used for the treatment of immature permanent teeth with periapical lesion, as part of a regenerative endodontic treatment procedure.

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참고문헌

  1. Fouad AF. The microbial challenge to pulp regeneration. Adv Dent Res 2011;23:285-289. https://doi.org/10.1177/0022034511405388
  2. Gomes-Filho JE, Duarte PC, de Oliveira CB, Watanabe S, Lodi CS, Cintra LT, Bernabe PF. Tissue reaction to a triantibiotic paste used for endodontic tissue selfregeneration of nonvital immature permanent teeth. J Endod 2012;38:91-94.
  3. Villat C, Grosgogeat B, Seux D, Farge P. Conservative approach of a symptomatic carious immature permanent tooth using a tricalcium silicate cement (Biodentine): a case report. Restor Dent Endod 2013;38:258-262. https://doi.org/10.5395/rde.2013.38.4.258
  4. Banchs F, Trope M. Revascularization of immature permanent teeth with apical periodontitis: new treatment protocol? J Endod 2004;30:196-200. https://doi.org/10.1097/00004770-200404000-00003
  5. Forghani M, Parisay I, Maghsoudlou A. Apexogenesis and revascularization treatment procedures for two traumatized immature permanent maxillary incisors: a case report. Restor Dent Endod 2013;38:178-181. https://doi.org/10.5395/rde.2013.38.3.178
  6. Murray PE, Garcia-Godoy F, Hargreaves KM. Regenerative endodontics: a review of current status and a call for action. J Endod 2007;33:377-390. https://doi.org/10.1016/j.joen.2006.09.013
  7. Huang GT. Pulp and dentin tissue engineering and regeneration: current progress. Regen Med 2009;4:697-707. https://doi.org/10.2217/rme.09.45
  8. Akgun OM, Altun C, Guven G. Use of triple antibiotic paste as a disinfectant for a traumatized immature tooth with a periapical lesion: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009;108:e62-65. https://doi.org/10.1016/j.tripleo.2009.04.015
  9. Ogino Y, Ayukawa Y, Kukita T, Koyano K. The contribution of platelet-derived growth factor, transforming growth factor-beta1, and insulin-like growth factor-I in platelet-rich plasma to the proliferation of osteoblastlike cells. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006;101:724-729. https://doi.org/10.1016/j.tripleo.2005.08.016
  10. Torabinejad M, Turman M. Revitalization of tooth with necrotic pulp and open apex by using platelet-rich plasma: a case report. J Endod 2011;37:265-268. https://doi.org/10.1016/j.joen.2010.11.004
  11. Bezgin T, Yilmaz AD, Celik BN, Sonmez H. Concentrated platelet-rich plasma used in root canal revascularization: 2 case reports. Int Endod J 2014;47: 41-49. https://doi.org/10.1111/iej.12144
  12. Andreasen FM. Pulpal healing following acute dental trauma: clinical and radiographic review. Pract Proced Aesthet Dent 2001;13:315-322.
  13. Beslot-Neveu A, Bonte E, Baune B, Serreau R, Aissat F, Quinquis L, Grabar S, Lasfargues JJ. Mineral trioxide aggregate versus calcium hydroxide in apexification of non vital immature teeth: study protocol for a randomized controlled trial. Trials 2011;12:174. https://doi.org/10.1186/1745-6215-12-174
  14. Chen MY, Chen KL, Chen CA, Tayebaty F, Rosenberg PA, Lin LM. Responses of immature permanent teeth with infected necrotic pulp tissue and apical periodontitis/abscess to revascularization procedures. Int Endod J 2012;45:294-305. https://doi.org/10.1111/j.1365-2591.2011.01978.x
  15. American Association of Endodontists. Glossary of endodontic terms. 7th ed. Chicago: American Association of Endodontists; 2003.
  16. Walia T, Chawla HS, Gauba K. Management of wide open apices in non-vital permanent teeth with Ca(OH)2 paste. J Clin Pediatr Dent 2000;25:51-56.
  17. Rafter M. Apexification: a review. Dent Traumatol 2005;21:1-8. https://doi.org/10.1111/j.1600-9657.2004.00284.x
  18. Petrino JA, Boda KK, Shambarger S, Bowles WR, McClanahan SB. Challenges in regenerative endodontics: a case series. J Endod 2010;36:536-541. https://doi.org/10.1016/j.joen.2009.10.006
  19. Ding RY, Cheung GS, Chen J, Yin XZ, Wang QQ, Zhang CF. Pulp revascularization of immature teeth with apical periodontitis: a clinical study. J Endod 2009;35:745-749. https://doi.org/10.1016/j.joen.2009.02.009
  20. Hoshino E, Kurihara-Ando N, Sato I, Uematsu H, Sato M, Kota K, Iwaku M. In-vitro antibacterial susceptibility of bacteria taken from infected root dentine to a mixture of ciprofloxacin, metronidazole and minocycline. Int Endod J 1996;29:125-130. https://doi.org/10.1111/j.1365-2591.1996.tb01173.x
  21. Chopra I, Roberts M. Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance. Microbiol Mol Biol Rev 2001;65:232-260. https://doi.org/10.1128/MMBR.65.2.232-260.2001
  22. Agwuh KN, MacGowan A. Pharmacokinetics and pharmacodynamics of the tetracyclines including glycylcyclines. J Antimicrob Chemother 2006;58:256-265. https://doi.org/10.1093/jac/dkl224
  23. Kim JH, Kim Y, Shin SJ, Park JW, Jung IY. Tooth discoloration of immature permanent incisor associated with triple antibiotic therapy: a case report. J Endod 2010;36:1086-1091. https://doi.org/10.1016/j.joen.2010.03.031
  24. Reynolds K, Johnson JD, Cohenca N. Pulp revascularization of necrotic bilateral bicuspids using a modified novel technique to eliminate potential coronal discoloration: a case report. Int Endod J 2009;42:84-92. https://doi.org/10.1111/j.1365-2591.2008.01467.x
  25. Torabinejad M, Chivian N. Clinical applications of mineral trioxide aggregate. J Endod 1999;25:197-205. https://doi.org/10.1016/S0099-2399(99)80142-3
  26. Cotti E, Mereu M, Lusso D. Regenerative treatment of an immature, traumatized tooth with apical periodontitis: report of a case. J Endod 2008;34:611-616. https://doi.org/10.1016/j.joen.2008.02.029
  27. Rudagi KB, Rudagi B. One-step apexification in immature tooth using grey mineral trioxide aggregate as an apical barrier and autologus platelet rich fibrin membrane as an internal matrix. J Conserv Dent 2012; 15:196-199. https://doi.org/10.4103/0972-0707.94582
  28. Shivashankar VY, Johns DA, Vidyanath S, Kumar MR. Platelet rich fibrin in the revitalization of tooth with necrotic pulp and open apex. J Conserv Dent 2012;15: 395-398. https://doi.org/10.4103/0972-0707.101926
  29. Hotwani K, Sharma K. Platelet rich fibrin - a novel acumen into regenerative endodontic therapy. Restor Dent Endod 2014;39:1-6. https://doi.org/10.5395/rde.2014.39.1.1
  30. Liu ZN, Jiang T, Wang YX. Platelet-riched plasma promotes potential mineralizing capacity of human dental pulp cells in vivo. Beijing Da Xue Xue Bao 2011; 43:276-279.
  31. Torabinejad M, Faras H. A clinical and histological report of a tooth with an open apex treated with regenerative endodontics using platelet-rich plasma. J Endod 2012;38:864-868. https://doi.org/10.1016/j.joen.2012.03.006
  32. Jadhav GR, Shah N, Logani A. Comparative outcome of revascularization in bilateral, non-vital, immature maxillary anterior teeth supplemented with or without platelet rich plasma: a case series. J Conserv Dent 2013; 16:568-572. https://doi.org/10.4103/0972-0707.120932

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  2. Platelet preparations in dentistry: How? Why? Where? When? vol.4, pp.2, 2015, https://doi.org/10.5321/wjs.v4.i2.39
  3. The impact of autologous platelet concentrates on endodontic healing: a systematic review vol.27, pp.7, 2016, https://doi.org/10.1080/09537104.2016.1226497
  4. A scoping review of root canal revascularization: relevant aspects for clinical success and tissue formation vol.50, pp.9, 2016, https://doi.org/10.1111/iej.12711
  5. Mineral trioxide aggregate and other bioactive endodontic cements: an updated overview - part II: other clinical applications and complications pp.01432885, 2018, https://doi.org/10.1111/iej.12843
  6. Alternative to Avoid Tooth Discoloration after Regenerative Endodontic Procedure: A Systematic Review vol.29, pp.5, 2018, https://doi.org/10.1590/0103-6440201802132
  7. Platelet concentrates for revitalization of immature necrotic teeth: a systematic review of the clinical studies vol.27, pp.5, 2014, https://doi.org/10.3109/09537104.2015.1131255
  8. Effects of Epigallocatechin Gallate, an Antibacterial Cross-linking Agent, on Proliferation and Differentiation of Human Dental Pulp Cells Cultured in Collagen Scaffolds vol.43, pp.2, 2017, https://doi.org/10.1016/j.joen.2016.10.017
  9. Coronal tooth discoloration induced by regenerative endodontic treatment using different scaffolds and intracanal coronal barriers: a 6-month ex vivo study vol.44, pp.3, 2014, https://doi.org/10.5395/rde.2019.44.e25
  10. Bone, Periodontal and Dental Pulp Regeneration in Dentistry: A Systematic Scoping Review vol.30, pp.2, 2014, https://doi.org/10.1590/0103-6440201902053
  11. Different Approaches to the Regeneration of Dental Tissues in Regenerative Endodontics vol.11, pp.4, 2021, https://doi.org/10.3390/app11041699