Biomaterials Research (생체재료학회지)

Korean Society for Biomaterials (한국생체재료학회)
권호 표지

Nanofibrous Scaffolds in Biomedical Applications

  • Gupta, Kailash Chandra (Department of Polymer Science and Engineering, Kyungpook National University) ;
  • Haider, Adnan (Department of Polymer Science and Engineering, Kyungpook National University) ;
  • Choi, Yu-Ri (Department of Polymer Science and Engineering, Kyungpook National University) ;
  • Kang, Inn-Kyu (Department of Polymer Science and Engineering, Kyungpook National University)
  • Received : 2014.02.21
  • Accepted : 2014.04.30
  • Published : 2014.06.01
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Abstract

Nanofibrous scaffolds are artificial extracellular matrices which provide natural environment for tissue formation. In comparison to other forms of scaffolds, the nanofibrous scaffolds promote cell adhesion, proliferation and differentiation more efficiently due to having high surface to volume ratio. Although scaffolds for tissue engineering have been fabricated by various techniques but electrospun nanofibrous scaffolds have shown great potential in the fields of tissue engineering and regeneration. This review highlights the applications and importance of electrospun nanofibrous scaffolds in various fields of biomedical applications ranging from drug delivery to wound healing. Attempts have also been made to highlights the advantages and disadvantages of nanofirbous scaffolds fabricated for biomedical applications using technique of electrospinning. The role of various factors controlling drug distribution in electrospun nanofibrous scaffold is also discussed to increase the therapeutic efficiency of nanofibrous scaffolds in wound healing and drug delivery applications.

Keywords

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