Journal of Radiation Industry (방사선산업학회지)

Korean Society of Radiation Industry (한국방사선산업학회)
권호 표지

Investigation of the Susceptibility of Arctic Arthrobacter sp. PAMC 25486 to Mutagens

극지미생물 Arthrobacter sp. PAMC 25486의 돌연변이 유발 물질에 대한 감수성 평가

  • Kim, Sang-geun (Department of Biotechnology and Bioengineering, Chonnam National University) ;
  • Choi, Jong-il (Department of Biotechnology and Bioengineering, Chonnam National University) ;
  • Han, Se Jong (Division of Life Sciences, Korea Polar Research Institute)
  • 김상근 (전남대학교 생물공학과) ;
  • 최종일 (전남대학교 생물공학과) ;
  • 한세종 (극지연구소 극지생명과학연구부)
  • Received : 2014.09.03
  • Accepted : 2014.09.26
  • Published : 2014.09.30

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Abstract

This study was conducted to investigate the sensitivity of Arthrobacter sp. PAMC 25486 to various mutagens. ${\gamma}-ray$, UV-ray, Ethyl methane sulfonate (EMS) and hydrogen peroxide ($H_2O_2$) were used as mutagen, and the survival rate of Arthrobacter sp. was measured at various doses of ${\gamma}-ray$ and UV-ray, and concentrations of EMS and $H_2O_2$. Decimal reduction dose ($D_{10}$ value) of Arthrobacter sp. was determined 370 Gy for a gamma irradiation treatment, 0.019 J for a UV ray, 2.5 mM for EMS, and 230 mM for $H_2O_2$. This result will be applied for the development of superior mutant strain of Arctic bacteria producing valuable compounds.

Keywords

Acknowledgement

Supported by : 극지연구소