The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology (한방안이비인후피부과학회지)

The Society of Korean Medicine Ophthalmology, Otolaryngology & Dermatology (대한한방안이비인후피부과학회)
권호 표지
DOI QR코드

DOI QR Code

A Clinical Study for the Effect of External Applications Containing Herbal Extracts on Mild Atopic Dermatitis Patients

경증의 아토피 환자에서 한약 추출물 함유 외용제에 대한 임상 연구

  • Kang, Min-Seo (Dept. of Oriental Ophthalmology, Otolaryngology & Dermatology, College of Korean medicine, Semyung University) ;
  • Kim, Jeung-Beum (Dept. of Oriental Pathology, College of Korean medicine, Semyung University) ;
  • Kim, Hee-Taek (Dept. of Oriental Ophthalmology, Otolaryngology & Dermatology, College of Korean medicine, Semyung University)
  • 강민서 (세명대학교 한의과대학 안이비인후피부과학교실) ;
  • 김정범 (세명대학교 한의과대학 병리학교실) ;
  • 김희택 (세명대학교 한의과대학 안이비인후피부과학교실)
  • Received : 2014.07.08
  • Accepted : 2014.08.14
  • Published : 2014.08.25
Download PDF
⟨ Previous Next ⟩

Abstract

Objectives : The purpose of this study is to confirm the effects of external applications(CLANCHE SM A Clinic) containing herbal extracts on patient with atopic dermatitis. Methods : A total of 24 patients who visited Semyung Oriental Medical Center from January 15th, 2014 to February 20th, 2014 were included in the study. In this study, the patients were treated with external applications(CLANCHE SM A Clinic) containing herbal extracts. For 4 weeks of gross examination and instrumental assesment were made before and after the study. Results : 1. In the primary endpoint, SCORAD index showed a statistically significant decline. 2. In the secondary endpoint, index of skin hydration and index of TEWL showed statistical significance. 3. In the secondary endpoint, index of skin pH showed no statistically significant result. 4. To evaluate the safety of the products for the human body, vital sign check were conducted and showed no statistically significant result. And There were no severe adverse events during this study. Therefore, it is suggested that the safety of the products, if used for certain period, should be safe for the human body. 5. In global assesment of efficacy, both experimenter and subjects evaluated external applications were effective. Conclusions : According to the above experiments, it is suggested that external applications(CLANCHE SM A Clinic) containing herbal extracts should be effective for the atopic dermatitis.

Keywords

Acknowledgement

Supported by : 산업통상자원부

References

  1. O MJ, Yoo YB, Lim SH, Kim HT. A Clinical Study for the Effect of Ointment Contained Takrisodok-Eum on Recovering the Damaged Skin Barrier by Atopic Dermatitis. J Korean Med Ophthalmol Otolaryngol Dermatol, 2011;24(3)84-105.
  2. Joo HA, Bae HJ, Park MC, Baek SC, Hong SH, Yang HJ, et al. A Clinical Study for the Effect of Cosmetic Cream Containing Samwhangsejegamibang Extracts on Atopic Dermatitis Patients. J Korean Med Ophthalmol Otolaryngol Dermatol. 2012;25(3)129-46. https://doi.org/10.6114/jkood.2012.25.3.129
  3. Hong JH, Jung HA. Clinical Efficacy of External Application Containing Betula platyphyllae Cortex, Viticis Fructus, Agrimoniae herba in Atopic Dermatitis. J Korean Med Ophthalmol Otolaryngol Dermatol. 2014;27(1)1-16. https://doi.org/10.6114/jkood.2014.27.1.001
  4. Benn CS, Melbye M, Wohlfahrt J, Bjorksten B, Aaby P. Cohort Study of Sibling Effect, Infectious Diseases, and Risk of Atopic Dermatitis During First 18 Months of Life. Bmj. 2004;328(7450):1223. https://doi.org/10.1136/bmj.38069.512245.FE
  5. KDA Textbook Editing Board. Dermatology. 5th edition. Seoul:Ryo Moon Gak. 2008:170-8.
  6. Ahn SG, Jang KH, Song JW, Cheon SH. Common Skin Disease. 2nd edition. Seoul:Dr's Book. 2009:13-42
  7. Cho JM, Hong EJ, Seo HS. Reviewing Research on Laser Therapy of Atopic Dermatitis. J Korean Med Ophthalmol Otolaryngol Dermatol, 2013;26(1)82-96. https://doi.org/10.6114/jkood.2013.26.1.082
  8. Kim SH, Yun DC, Kim HT, Ho DS, Yoon KS. A Clinical Research of Atopic Dermatitis Treated by Yeongyuseungmatang in Cosmetics. J Korean Med Ophthalmol Otolaryngol Dermatol. 2008;21(2):126-41.
  9. Hwang SY, Hwang-Bo M, Jee SY, Kim SY, Kwon YG, Seo JC. A Clinical Study of Atopic Dermatitis Treated by External Application with Gynostemma Pentaphyllum MAKINO in Cosmetics. J Korean Med Ophthalmol Otolaryngol Dermatol. 2007;20(3):212-21.
  10. Kim CH, Kim JT, Jung HA, Roh SS. Clinical Efficacy of External Preparation Containing Herbal Extracts in Atopic Dermatitis Patients. J Korean Med Ophthalmol Otolaryngol Dermatol. 2007;20(2):187-98.
  11. Park ES, Lee JY. One Case of Atopic Dematitis Treated by Horminis Placenta External Wet Therapy. J Korean Orient Pediatric. 2010;24(1):46-56
  12. Ahn SG, Park BD, Won JH, Cheon SH. An Atlas of Atopic Eczema. Seoul:Koonja publishing INC. 2007;107-15.
  13. Kim KH, Jung HA. Clinical Study for the Efficacy of External Preparation Containing Sophorae Radix, Aurantii Immaturus Fructus, Schizonepetae Spica, Forsythia fructus and Portulacea Herba Extract on Atopic Dermatitis. J Korean Med Ophthalmol Otolaryngol Dermatol, 2014;27(1)17-36. https://doi.org/10.6114/jkood.2014.27.1.017
  14. Kang SJ, Kim AJ, Lee YH, Lee MS, Joung KH, Cho NJ. The Enhancing Effect of Atopic Dermatitis by Cosmetics Containing Estern Medical Herbs. Journal of the Korea Academia-Industrial cooperation Society. 2009;10(11):3500-5. https://doi.org/10.5762/KAIS.2009.10.11.3500
  15. Cho WA, Chun SJ, Lee JT. Study on Safety and Improvement of Skin Condition of Oriental Herbal Cosmetics Containing the Cuscuta Japonica Choisy. Journal of the Korean society of cosmetology. 2008;14(3):754-62
  16. The National College of Oriental Medicine Herbology Classroom. Herbology. Seoul: Youngrimsa. 2008:205-6, 207-9, 216-23, 225-6, 242-3, 251-2, 392-3, 576-8, 583-5, 617-9, 629-31, 651-2, 657-8.

Cited by

  1. The Review of Clinical Studies Published in The Journal of Korean Medical Ophthalmology & Otolaryngology & Dermatology vol.27, pp.4, 2014, https://doi.org/10.6114/jkood.2014.27.4.001
  2. Retrospective Study about the Effectiveness of Korean Medicine Treatment on 89 Severe Atopic Dermatitis Patients vol.29, pp.2, 2016, https://doi.org/10.6114/jkood.2016.29.2.161
  3. 침시술이 경피수분 손실량과 피부 수분함유량에 미치는 임상적 연구 vol.32, pp.4, 2014, https://doi.org/10.15188/kjopp.2018.08.32.4.271
  4. 곡지혈 매선침 시술이 경피수분 손실량에 미치는 영향 vol.32, pp.4, 2014, https://doi.org/10.15188/kjopp.2018.08.32.4.291
  5. 아토피성 피부로 건조함을 가진 대상자에 대한 환삼덩굴추출물 함유 기능성 화장품의 유효성 및 안전성을 평가하기 위한 임상적 연구 vol.32, pp.2, 2014, https://doi.org/10.6114/jkood.2019.32.2.024