The Korean journal of internal medicine

  • 제29권2호
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  • Pages.231-235
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  • 2014
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  • 1226-3303(pISSN)
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  • 2005-6648(eISSN)
대한내과학회 (The Korean Association of Internal Medicine)
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DOI QR코드

DOI QR Code

Dermatomyositis associated with hepatitis B virus-related hepatocellular carcinoma

  • Yang, Suh Yoon (Department of Internal Medicine, Chung-Ang University College of Medicine) ;
  • Cha, Bong Ki (Department of Internal Medicine, Chung-Ang University College of Medicine) ;
  • Kim, Gihyeon (Department of Radiology, Chung-Ang University College of Medicine) ;
  • Lee, Hyun Woong (Department of Internal Medicine, Chung-Ang University College of Medicine) ;
  • Kim, Jae Gyu (Department of Internal Medicine, Chung-Ang University College of Medicine) ;
  • Chang, Sae Kyung (Department of Internal Medicine, Chung-Ang University College of Medicine) ;
  • Kim, Hyung Joon (Department of Internal Medicine, Chung-Ang University College of Medicine)
  • 투고 : 2012.09.26
  • 심사 : 2012.11.02
  • 발행 : 2014.03.01
⟨ 이전 논문 다음 논문 ⟩

초록

Dermatomyositis is an idiopathic inflammatory myopathy with typical cutaneous manifestations. It has been proposed that dermatomyositis may be caused by autoimmune responses to viral infections. Previous studies have shown an association between dermatomyositis and malignant tumors such as ovarian cancer, lung cancer, and colorectal cancer. However, a chronic hepatitis B virus (HBV) infection associated with dermatomyositis and hepatocellular carcinoma (HCC) has been very rarely reported. Here, we report a rare case of dermatomyositis coinciding with HBV-associated HCC. A 55-year-old male was confirmed to have HCC and dermatomyositis based on proximal muscle weakness, typical skin manifestations, elevated muscle enzyme levels, and muscle biopsy findings. This case suggests that HCC and/or a chronic HBV infection may be factors in the pathogenesis of dermatomyositis through a paraneoplastic mechanism.

키워드

참고문헌

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피인용 문헌

  1. Cutaneous manifestations of hepatocellular cancer (HCC) vol.10, pp.10, 2016, https://doi.org/10.1080/17474124.2016.1229182
  2. Risk of Malignancy in Dermatomyositis and Polymyositis : A Systematic Review and Meta-Analysis vol.21, pp.2, 2014, https://doi.org/10.1177/1203475416665601
  3. Dermatomyositis Induced by Hepatitis B Virus-related Hepatocellular Carcinoma: A Case Report and Review of the Literature vol.56, pp.14, 2017, https://doi.org/10.2169/internalmedicine.56.7595
  4. Dermatomyositis as an extrahepatic manifestation of hepatitis B virus-related hepatocellular carcinoma : A case report and literature review vol.97, pp.33, 2014, https://doi.org/10.1097/md.0000000000011586
  5. Expression of the OAS Gene Family Is Highly Modulated in Subjects Affected by Juvenile Dermatomyositis, Resembling an Immune Response to a dsRNA Virus Infection vol.19, pp.9, 2014, https://doi.org/10.3390/ijms19092786
  6. Hepatitis B virus-related liver cirrhosis complicated with dermatomyositis: A case report vol.7, pp.10, 2019, https://doi.org/10.12998/wjcc.v7.i10.1206
  7. Polymyositis and dermatomyositis – challenges in diagnosis and management vol.2, pp.None, 2014, https://doi.org/10.1016/j.jtauto.2019.100018
  8. Value of 18 F-FDG PET/CT in the detection of occult malignancy in patients with dermatomyositis vol.6, pp.4, 2020, https://doi.org/10.1016/j.heliyon.2020.e03707