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Rosai-Dorfman Disease as a Solitary Lesion of the Tibia

경골에 단독으로 발생한 Rosai-Dorfman병

  • Kong, Chang-Bae (Department of Orthopedic Surgery, Korea Cancer Center Hospital) ;
  • Lee, Jung-Wook (Department of Orthopedic Surgery, Korea Cancer Center Hospital) ;
  • Cho, Sang-Hyun (Department of Orthopedic Surgery, Korea Cancer Center Hospital) ;
  • Song, Won-Seok (Department of Orthopedic Surgery, Korea Cancer Center Hospital) ;
  • Cho, Wan-Hyeong (Department of Orthopedic Surgery, Korea Cancer Center Hospital) ;
  • Koh, Jae-Soo (Department of Pathology, Korea Cancer Center Hospital) ;
  • Jeon, Dae-Geun (Department of Orthopedic Surgery, Korea Cancer Center Hospital) ;
  • Lee, Soo-Yong (Department of Orthopedic Surgery, Korea Cancer Center Hospital)
  • Received : 2014.03.14
  • Accepted : 2014.06.03
  • Published : 2014.06.30

Abstract

Rosai-Dorfman disease (RDD) is an idiopathic histioproliferative disorder of lymph node and extranodal site. Bone involvement is very rare. We report a case of extranodal RDD of the tibia in 32-year old male. The patient presented with pain with no evidence of lymphadenopathy. Clinico-radiologic diagnosis was metastatic carcinoma or Langerhans cell histiocytosis, but, histopathologic examination confirmed the diagnosis with RDD. We performed curettage on the osteolytic lesion of tibia. In South Korea, there was no report about RDD of the extremity and we want to report this case with review of the literature.

Rosai-Dorfman병은 특발성 양성 조직구 증식성 질환으로 결절형과 결절외형으로 분류되는 질환이며 골 침범은 매우 드물다. 증례는 32세 남자로 좌측 하퇴의 통증을 주소로 내원하였으며 림프절병증은 동반하지 않았다. 임상 및 영상학적으로 전이암, Langerhans 세포 조직구증 등이 의심되어 병변에 대한 절개 생검 시행하였고, 조직 검사 결과 Rosai-Dorfman병으로 진단되어 골소파술 시행하였다. 국내에서 Rosai-Dorfaman병이 사지에 단독으로 발생한 증례는 없기에 저자들은 이를 문헌 고찰과 함께 보고하고자 한다.

Keywords

References

  1. Demicco EG, Rosenberg AE, Bjornsson J, Rybak LD, Unni KK, Nielsen GP. Primary Rosai-Dorfman disease of bone: a clinicopathologic study of 15 cases. Am J Surg Pathol. 2010;34:1324-33. https://doi.org/10.1097/PAS.0b013e3181ea50b2
  2. Lai KL, Abdullah V, Ng KS, Fung NS, van Hasselt CA. Rosai- Dorfman disease: presentation, diagnosis, and treatment. Head Neck. 2013;35:E85-8. https://doi.org/10.1002/hed.21930
  3. George J, Stacy G, Peabody T, Montag A. Rosai-Dorfman disease manifesting as a solitary lesion of the radius in a 41-yearold woman. Skeletal Radiol. 2003;32:236-9. https://doi.org/10.1007/s00256-002-0613-x
  4. Orvets ND, Mayerson JL, Wakely PE Jr. Extranodal Rosai- Dorfman disease as solitary lesion of the tibia in a 56-year-old woman. Am J Orthop (Belle Mead NJ). 2013;42:420-2.
  5. Shin BJ, Lee JC, Nam JS, et al. Rosai-Dorfman disease occurred in epidural space of the thoracic spinal canal. J Korean Soc Spine Surg. 2006;13:64-8. https://doi.org/10.4184/jkss.2006.13.1.64
  6. Tripathy K, Misra A, Sahu AK, Patnaik K. Extranodal Rosai-Dorfman disease in a carpal bone. Indian J Orthop. 2012;46:487-9. https://doi.org/10.4103/0019-5413.98836
  7. Rittner RE, Baumann U, Laenger F, Hartung D, Rosenthal H, Hueper K. Whole-body diffusion-weighted MRI in a case of Rosai-Dorfman disease with exclusive multifocal skeletal involvement. Skeletal Radiol. 2012;41:709-13. https://doi.org/10.1007/s00256-011-1328-7