Radiation Oncology Journal

  • 제32권2호
  • /
  • Pages.95-98
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  • 2014
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  • 2234-1900(pISSN)
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  • 2234-3156(eISSN)
대한방사선종양학회 (The Korean Society for Radiation Oncology)
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Aggressive clinical course of extramammary Paget disease after radiotherapy

  • Choi, Yunseon (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Park, Won (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Lee, Jeeyun (Department of Hematology and Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Cho, Eun Yoon (Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Moon, Goo-Hyun (Department of Plastic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine)
  • 투고 : 2014.03.26
  • 심사 : 2014.05.07
  • 발행 : 2014.06.30
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초록

Extramammary Paget disease (EMPD) is a rare disease, especially in Asian populations. Surgical resection is considered the primary treatment option. Recently, radiotherapy has been suggested as an EMPD treatment, either as an alternative to surgical resection or in combination with surgical resection. This report reviewed a patient with EMPD who was treated with wide excision of the EMPD site followed by radiotherapy for remaining gross lymph node metastases. The aim of this report was to determine the optimal treatment for advanced EMPD.

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참고문헌

  1. Siesling S, Elferink MA, van Dijck JA, Pierie JP, Blokx WA. Epidemiology and treatment of extramammary Paget disease in the Netherlands. Eur J Surg Oncol 2007;33:951-5. https://doi.org/10.1016/j.ejso.2006.11.028
  2. Lam C, Funaro D. Extramammary Paget's disease: summary of current knowledge. Dermatol Clin 2010;28:807-26. https://doi.org/10.1016/j.det.2010.08.002
  3. Shepherd V, Davidson EJ, Davies-Humphreys J. Extramammary Paget's disease. BJOG 2005;112:273-9. https://doi.org/10.1111/j.1471-0528.2004.00438.x
  4. Aoyagi S, Akiyama M, Shimizu H. High expression of Ki-67 and cyclin D1 in invasive extramammary Paget's disease. J Dermatol Sci 2008;50:177-84. https://doi.org/10.1016/j.jdermsci.2007.12.002
  5. Hata M, Koike I, Wada H, et al. Radiation therapy for extramammary Paget's disease: treatment outcomes and prognostic factors. Ann Oncol 2014;25:291-7. https://doi.org/10.1093/annonc/mdt478
  6. Richter CE, Hui P, Buza N, et al. HER-2/NEU overexpression in vulvar Paget disease: the Yale experience. J Clin Pathol 2010; 63:544-7. https://doi.org/10.1136/jcp.2010.077446
  7. Hata M, Omura M, Koike I, et al. Role of radiotherapy as curative treatment of extramammary Paget's disease. Int J Radiat Oncol Biol Phys 2011;80:47-54. https://doi.org/10.1016/j.ijrobp.2010.01.073
  8. Mann J, Lavaf A, Tejwani A, Ross P, Ashamalla H. Perianal Paget disease treated definitively with radiotherapy. Curr Oncol 2012;19:e496-500.
  9. Hata M, Koike I, Wada H, et al. Radiation therapy for lymph node metastasis from extramammary Paget's disease. J Eur Acad Dermatol Venereol. 2013 May 13 [Epub]. http://dx.doi. org/10.1111/jdv.12185.
  10. Luk NM, Yu KH, Yeung WK, Choi CL, Teo ML. Extramammary Paget's disease: outcome of radiotherapy with curative intent. Clin Exp Dermatol 2003;28:360-3. https://doi.org/10.1046/j.1365-2230.2003.01301.x
  11. Hatta N, Morita R, Yamada M, et al. Sentinel lymph node biopsy in patients with extramammary Paget's disease. Dermatol Surg 2004;30:1329-34.
  12. Beleznay KM, Levesque MA, Gill S. Response to 5-fluorouracil in metastatic extramammary Paget disease of the scrotum presenting as pancytopenia and back pain. Curr Oncol 2009; 16:81-3.
  13. Matsushita S, Yonekura K, Mera K, Kawai K, Kanekura T. Successful treatment of metastatic extramammary Paget's disease with S-1 and docetaxel combination chemotherapy. J Dermatol 2011;38:996-8. https://doi.org/10.1111/j.1346-8138.2010.01149.x
  14. Mochitomi Y, Sakamoto R, Gushi A, et al. Extramammary Paget's disease/carcinoma successfully treated with a combination chemotherapy: report of two cases. J Dermatol 2005;32:632-7. https://doi.org/10.1111/j.1346-8138.2005.tb00812.x

피인용 문헌

  1. Primary extramammary invasive Paget’s vulvar disease: what is the standard, what are the challenges and what is the future for radiotherapy? vol.16, pp.None, 2014, https://doi.org/10.1186/s12885-016-2622-5