MVCT를 이용한 치료 간(Interfraction) 그리고 치료 중(Intrafraction) 내부 장기 변화 분석

Analysis of change of internal organ in the Inter-and Intrafraction using MVCT

  • 정원석 (경희의료원 방사선종양학과) ;
  • 김주호 (연세암센터 방사선종양학과) ;
  • 김영재 (대구보건대학교 방사선과) ;
  • 신령미 (경희의료원 방사선종양학과) ;
  • 오정훈 (경희의료원 방사선종양학과) ;
  • 정건아 (경희의료원 방사선종양학과) ;
  • 조준영 (경희의료원 방사선종양학과) ;
  • 김기철 (경희의료원 방사선종양학과) ;
  • 최태규 (경희의료원 방사선종양학과)
  • Jung, Won Seok (Department of Radiation Oncology, Kyunghee College Hospital) ;
  • Kim, Ju Ho (Department of Radiation Oncology, Yonsei Cancer Center) ;
  • Kim, Young Jae (Department of Radiological Technology, Daegu Health College) ;
  • Shin, Ryung Mi (Department of Radiation Oncology, Kyunghee College Hospital) ;
  • Oh, Jeong Hun (Department of Radiation Oncology, Kyunghee College Hospital) ;
  • Jeong, Geon A (Department of Radiation Oncology, Kyunghee College Hospital) ;
  • Jo, Jun Young (Department of Radiation Oncology, Kyunghee College Hospital) ;
  • Kim, Gi Chul (Department of Radiation Oncology, Kyunghee College Hospital) ;
  • Choi, Tae Kyu (Department of Radiation Oncology, Kyunghee College Hospital)
  • 투고 : 2014.03.25
  • 심사 : 2014.04.30
  • 발행 : 2014.06.30

초록

목 적 : 다양한 치료 부위에 따라 MVCT(Megavoltage computed tomography)를 이용하여 치료 중(Intrafraction), 치료 간(Interfraction)의 장기 위치 변화를 측정하여 평가하고자 한다. 대상 및 방법 : 본 연구에서 두 경부(Head & neck), 흉부(Thorax), 간(Liver), 전립선(Prostate) 종양을 가진 48명 환자들은 전체 치료 과정동안 다양한 MVCT scan을 시행하였다. 평균 환자 당 60개의 MVCT 영상을 획득하여 분석하였다. 결 과 : 치료 간(Interfraction)오차는 흉부와 복부 그리고 골반이 종 방향(Longitudinal, Y)에서 3 mm 이상의 차이를 보였다. 치료 중(Intrafraction) 변화를 알아보기 위해 치료가 끝난 후에 MVCT를 찍어 확인한 후 치료 중(Intrafraction) 움직임 차이는 종 방향에서 2 mm 내외로 나타났다. 또한 치료 전과 후의 움직임의 변화로 인해 치료 간 그리고 치료 중의 차이를 확인하였다. 결 론 : 본 연구에서도 두 경부(Head & neck), 흉부(Thorax), 간(Liver), 전립선암(Prostate cancer) 환자들의 치료 간(Interfraction) 변화와 치료 중(Intrafraction)변화를 통해 적절한 고정 기구와 표적 여백의 윤곽을 완성하는데 도움이 될 거라 사료된다.

Purpose : Depending on a variety of therapeutic areas using MVCT(Megavoltage computed tomography) intra-and interfraction is to evaluate changes in patient position. Materials and Methods : In this study, head and neck, thorax, liver, and prostate tumor patients, 48 people with a full course of treatment for patients with various MVCT scan was performed. Average 60 per patient MVCT images were acquired and analyzed. Results : Interfraction error thorax and abdomen, and pelvis in the longitudinal difference was more than 3 mm. Intrafraction to see a change after the end of treatment MVCT taken, and the results confirmed Intrafraction 2 mm in motion around the longitudinal difference. In addition, due to changes in the movement before and after treatment, Inter-and Intrafraction difference was found. Conclusion : In the present study, the Head and Neck, Thorax, liver, prostate cancer in patients with inter-and intrafraction changes and target the appropriate fixtures to complete the outline of the margin would be helpful is considered.

키워드

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