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A Case of Intradural-Extramedullary Form of Primary Spinal Cysticercosis Misdiagnosed as an Arachnoid Cyst

  • Yoo, Minwook (Department of Neurosurgery, Spine Center, Seoul National University Bundang Hospital, Seoul National University College of Medicine) ;
  • Lee, Chang-Hyun (Department of Neurosurgery, Spine Center, Seoul National University Bundang Hospital, Seoul National University College of Medicine) ;
  • Kim, Ki-Jeong (Department of Neurosurgery, Spine Center, Seoul National University Bundang Hospital, Seoul National University College of Medicine) ;
  • Kim, Hyun-Jib (Department of Neurosurgery, Spine Center, Seoul National University Bundang Hospital, Seoul National University College of Medicine)
  • Received : 2013.06.26
  • Accepted : 2014.04.15
  • Published : 2014.04.28

Abstract

We describe a rare case of intradural-extramedullary primary spinal cysticercosis. A 42-year-old man visited our institute for lower back pain. He denied having consumed raw meet. Magnetic resonance (MR) images revealed an intradural pure cystic mass at the L3-L4 level. A radiologic diagnosis of spinal arachnoid cyst was established. Three years later, he complained of aggravated back pain, and follow-up MR examination showed a markedly expanded cyst, occupying the subarachnoid space from the T11 to the S1 level. L2 hemilaminectomy was performed, and a yellowish infected cyst bulged out through the dural opening. The cyst was removed en bloc. The histopathological findings of the cyst were consistent with parasitic infection. Serum enzyme-linked immunosorbent assay (ELISA) confirmed the presence of spinal cysticercosis. As there was no intracranial lesion, the final diagnosis was primary spinal cysticercosis, which is very rare. MR imaging is a sensitive diagnostic tool for detecting cystic lesions in the spine; however, it is difficult to distinguish cysticercosis from non-infectious cysts such as an arachnoid cyst without using gadolinium enhancement. Clinicians treating spinal cysts with an unusual clinical course should include cysticercosis as a differential diagnosis. We recommend contrast-enhanced MR imaging and serum ELISA in the diagnostic work-up of such cases.

Keywords

References

  1. Azfar SF, Kirmani S, Badar F, Ahmad I : Isolated intramedullary spinal cysticercosis in a 10-year-old female showing dramatic response with albendazole. J Pediatr Neurosci 6 : 52-54, 2011
  2. Bustos JA, Pretell EJ, Llanos-Zavalaga F, Gilman RH, Del Brutto OH, Garcia HH, et al. : Efficacy of a 3-day course of albendazole treatment in patients with a single neurocysticercosis cyst. Clin Neurol Neurosurg 108 : 193-194, 2006 https://doi.org/10.1016/j.clineuro.2004.12.013
  3. De Souza Queiroz L, Filho AP, Callegaro D, De Faria LL : Intramedullary cysticercosis. Case report, literature review and comments on pathogenesis. J Neurol Sci 26 : 61-70, 1975 https://doi.org/10.1016/0022-510X(75)90114-8
  4. Gupta S, Singh PK, Gupta B, Singh V, Azam A : Isolated primary intradural extramedullary spinal neurocysticercosis: a case report and review of literature. Acta Neurol Taiwan 18 : 187-192, 2009
  5. Hawk MW, Shahlaie K, Kim KD, Theis JH : Neurocysticercosis : a review. Surg Neurol 63 : 123-132; discussion 132, 2005 https://doi.org/10.1016/j.surneu.2004.02.033
  6. Jang JW, Lee JK, Lee JH, Seo BR, Kim SH : Recurrent primary spinal subarachnoid neurocysticercosis. Spine (Phila Pa 1976) 35 : e172-e175, 2010 https://doi.org/10.1097/BRS.0b013e3181b9d8b6
  7. Jongwutiwes U, Yanagida T, Ito A, Kline SE : Isolated intradural-extramedullary spinal cysticercosis : a case report. J Travel Med 18 : 284-287,2011 https://doi.org/10.1111/j.1708-8305.2011.00535.x
  8. Leite CC, Jinkins JR, Escobar BE, Magalhães AC, Gomes GC, Dib G, et al. : MR imaging of intramedullary and intradural-extramedullary spinal cysticercosis. AJR Am J Roentgenol 169 : 1713-1717, 1997 https://doi.org/10.2214/ajr.169.6.9393195
  9. Mohanty A, Venkatrama SK, Das S, Das BS, Rao BR, Vasudev MK : Spinal intramedullary cysticercosis. Neurosurgery 40 : 82-87, 1997
  10. Nash TE, Neva FA : Recent advances in the diagnosis and treatment of cerebral cysticercosis. N Engl J Med 311 : 1492-1496, 1984 https://doi.org/10.1056/NEJM198412063112307
  11. Park YS, Lee JK, Kim JH, Park KC : Cysticercosis of lumbar spine, mimicking spinal subarachnoid tumor. Spine J 11 : e1-e5, 2011 https://doi.org/10.1016/S1529-9430(11)01462-8
  12. Paterakis KN, Kapsalaki E, Hadjigeorgiou GM, Barbanis S, Fezoulidis I, Kourtopoulos H : Primary spinal intradural extramedullary cysticercosis. Surg Neurol 68 : 309-311; discussion 312, 2007 https://doi.org/10.1016/j.surneu.2006.10.060
  13. Rahalkar MD, Shetty DD, Kelkar AB, Kelkar AA, Kinare AS, Ambardekar ST : The many faces of cysticercosis. Clin Radiol 55 : 668-674, 2000 https://doi.org/10.1053/crad.2000.0494
  14. Shin SH, Hwang BW, Lee SJ, Lee SH : Primary extensive spinal subarachnoid cysticercosis. Spine (Phila Pa 1976) 37 : e1221-e1224, 2012 https://doi.org/10.1097/BRS.0b013e31825d291e

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