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The Potential Role of Intrathecal Nefopam in the Management of Neuropathic Pain

  • Ghobadifar, Mohamed Amin (Department of Student Research Committee, Jahrom University of Medical Sciences) ;
  • Kalani, Navid (Department of Anesthesiology, Jahrom University of Medical Sciences)
  • Received : 2014.04.22
  • Accepted : 2014.05.10
  • Published : 2014.07.01

Abstract

Keywords

References

  1. Kim KH, Abdi S. Rediscovery of nefopam for the treatment of neuropathic pain. Korean J Pain 2014; 27: 103-11. https://doi.org/10.3344/kjp.2014.27.2.103
  2. Cho SY, Park AR, Yoon MH, Lee HG, Kim WM, Choi JI. Antinociceptive effect of intrathecal nefopam and interaction with morphine in formalin-induced pain of rats. Korean J Pain 2013; 26: 14-20. https://doi.org/10.3344/kjp.2013.26.1.14
  3. Saghaei E, Moini Zanjani T, Sabetkasaei M, Naseri K. Enhancement of antinociception by co-administrations of nefopam, morphine, and nimesulide in a rat model of neuropathic pain. Korean J Pain 2012; 25: 7-15. https://doi.org/10.3344/kjp.2012.25.1.7
  4. Biella GE, Groppetti A, Novelli A, Fernandez-Sanchez MT, Manfredi B, Sotgiu ML. Neuronal sensitization and its behavioral correlates in a rat model of neuropathy are prevented by a cyclic analog of orphenadrine. J Neurotrauma 2003; 20: 593-601. https://doi.org/10.1089/089771503767168519
  5. Ulugol A, Oltulu C, Gunduz O, Citak C, Carrara R, Shaqaqi MR, et al. 5-HT7 receptor activation attenuates thermal hyperalgesia in streptozocin-induced diabetic mice. Pharmacol Biochem Behav 2012; 102: 344-8. https://doi.org/10.1016/j.pbb.2012.05.006
  6. Dam LJ, Hai L, Ha YM. Role of the 5-HT(7) receptor in the effects of intrathecal nefopam in neuropathic pain in rats. Neurosci Lett 2014; 566: 50-4. https://doi.org/10.1016/j.neulet.2014.02.021

Cited by

  1. Combined Use of Intrathecal Opioids and Dexmedetomidine in the Management of Neuropathic Pain vol.28, pp.2, 2015, https://doi.org/10.3344/kjp.2015.28.2.156
  2. Inadvertent intrathecal injection of nefopam during spinal anaesthesia vol.34, pp.5, 2017, https://doi.org/10.1097/EJA.0000000000000596