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Implementation of Ontology-based Clinical Decision Support System for Management of Interactions Between Antihypertensive Drugs and Diet

항고혈압제-식이 상호작용 관리를 위한 온톨로지 기반의 임상의사결정지원시스템 구현

  • Park, Jeong-Eun (College of Nursing, Kyungpook National University) ;
  • Kim, Hwa-Sun (Department of Medical Information Technology, Daegu Haany University) ;
  • Chang, Min-Jung (Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University) ;
  • Hong, Hae-Sook (College of Nursing, Kyungpook National University)
  • 박정은 (경북대학교 간호대학) ;
  • 김화선 (대구한의대학교 IT의료산업학과) ;
  • 장민정 (연세대학교 약학대학 종합약학연구소) ;
  • 홍해숙 (경북대학교 간호대학)
  • Received : 2014.03.03
  • Accepted : 2014.05.09
  • Published : 2014.06.30

Abstract

Purpose: The influence of dietary composition on blood pressure is an important subject in healthcare. Interactions between antihypertensive drugs and diet (IBADD) is the most important factor in the management of hypertension. It is therefore essential to support healthcare providers' decision making role in active and continuous interaction control in hypertension management. The aim of this study was to implement an ontology-based clinical decision support system (CDSS) for IBADD management (IBADDM). We considered the concepts of antihypertensive drugs and foods, and focused on the interchangeability between the database and the CDSS when providing tailored information. Methods: An ontology-based CDSS for IBADDM was implemented in eight phases: (1) determining the domain and scope of ontology, (2) reviewing existing ontology, (3) extracting and defining the concepts, (4) assigning relationships between concepts, (5) creating a conceptual map with CmapTools, (6) selecting upper ontology, (7) formally representing the ontology with Protege (ver.4.3), (8) implementing an ontology-based CDSS as a JAVA prototype application. Results: We extracted 5,926 concepts, 15 properties, and formally represented them using Protege. An ontology-based CDSS for IBADDM was implemented and the evaluation score was 4.60 out of 5. Conclusion: We endeavored to map functions of a CDSS and implement an ontology-based CDSS for IBADDM.

Keywords

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