Journal of Chest Surgery

The Korean Society for Thoracic and Cardiovascular Surgery (대한심장혈관흉부외과학회)
권호 표지
DOI QR코드

DOI QR Code

Primary Synovial Sarcoma of Lung

  • Cabuk, Devrim (Department of Medical Oncology, Kocaeli University Hospital) ;
  • Ustuner, Berna (Department of Medical Oncology, Kocaeli University Hospital) ;
  • Akgul, Asli Gul (Department of Thoracic Surgery, Kocaeli University Hospital) ;
  • Acikgoz, Ozgur (Department of Medical Oncology, Kocaeli University Hospital) ;
  • Yaprak, Busra (Department of Pathology, Kocaeli University Hospital) ;
  • Uygun, Kazim (Department of Medical Oncology, Kocaeli University Hospital) ;
  • Topcu, Salih (Department of Thoracic Surgery, Kocaeli University Hospital) ;
  • Muezzinoglu, Bahar (Department of Pathology, Kocaeli University Hospital)
  • Received : 2013.09.10
  • Accepted : 2013.12.26
  • Published : 2014.06.05
Download PDF
⟨ Previous Next ⟩

Abstract

Synovial sarcoma (SS) is a highly malignant tumor that accounts for 10% of all soft-tissue sarcomas. Primary SS arising from the lung is extremely rare, and the prognosis is poor. We report a case of pulmonary SS presenting with a mass lesion invading the right upper and middle lobes, extending to the mediastinum and the chest wall. After tru-cut biopsy, surgical resection was performed. The final diagnosis was SS (biphasic type) based on histological and immunohistochemical findings. There are no guidelines for optimal treatment due to the rarity of these tumors. Current treatment includes surgery and adjuvant chemotherapy and/or radiotherapy.

Keywords

References

  1. Rajwanshi A, Srinivas R, Upasana G. Malignant small round cell tumors. J Cytol 2009;26:1-10. https://doi.org/10.4103/0970-9371.54861
  2. Rossi G, Cavazza A, Sturm N, et al. Pulmonary carcinomas with pleomorphic, sarcomatoid, or sarcomatous elements: a clinicopathologic and immunohistochemical study of 75 cases. Am J Surg Pathol 2003;27:311-24. https://doi.org/10.1097/00000478-200303000-00004
  3. Nappi O, Wick MR. Sarcomatoid neoplasms of the respiratory tract. Semin Diagn Pathol 1993;10:137-47.
  4. Mankin HJ, Hornicek FJ. Diagnosis, classification, and management of soft tissue sarcomas. Cancer Control 2005;12:5-21.
  5. Essary LR, Vargas SO, Fletcher CD. Primary pleuropulmonary synovial sarcoma: reappraisal of a recently described anatomic subset. Cancer 2002;94:459-69. https://doi.org/10.1002/cncr.10188
  6. Hosono T, Hironaka M, Kobayashi A, et al. Primary pulmonary synovial sarcoma confirmed by molecular detection of SYT-SSX1 fusion gene transcripts: a case report and review of the literature. Jpn J Clin Oncol 2005;35:274-9. https://doi.org/10.1093/jjco/hyi073
  7. Etienne-Mastroianni B, Falchero L, Chalabreysse L, et al. Primary sarcomas of the lung: a clinicopathologic study of 12 cases. Lung Cancer 2002;38:283-9. https://doi.org/10.1016/S0169-5002(02)00303-3
  8. Kang MK, Cho KH, Lee YH, et al. Primary synovial sarcoma of the parietal pleura: a case report. Korean J Thorac Cardiovasc Surg 2013;46:159-61. https://doi.org/10.5090/kjtcs.2013.46.2.159
  9. Dennison S, Weppler E, Giacoppe G. Primary pulmonary synovial sarcoma: a case report and review of current diagnostic and therapeutic standards. Oncologist 2004;9:339-42. https://doi.org/10.1634/theoncologist.9-3-339

Cited by

  1. Primary pulmonary synovial sarcoma presenting with a large lump mass in the left upper mediastinum: A case report vol.11, pp.6, 2014, https://doi.org/10.3892/etm.2016.3237