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A Case of IgG4-Related Disease Presenting as Massive Pleural Effusion and Thrombophlebitis

  • Choi, Jong Hyun (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine) ;
  • Sim, Jae Kyeom (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine) ;
  • Oh, Jee Youn (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine) ;
  • Lee, Eun Joo (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine) ;
  • Hur, Gyu Young (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine) ;
  • Lee, Seung Heon (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine) ;
  • Lee, Sung Yong (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine) ;
  • Kim, Je Hyeong (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine) ;
  • Lee, Sang Yeub (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine) ;
  • Shin, Chol (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine) ;
  • Shim, Jae Jeong (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine) ;
  • In, Kwang Ho (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine) ;
  • Kang, Kyung Ho (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine) ;
  • Min, Kyung Hoon (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine)
  • 투고 : 2013.10.24
  • 심사 : 2013.10.31
  • 발행 : 2014.04.30

초록

Immunoglobulin (Ig) G4-related disease is a recently recognized systemic fibroinflammatory condition characterized by a lymphoplasmacytic infiltrate rich in IgG4-positive plasma cells with elevated circulating levels of IgG4. The disease can either be localized to one or two organs, or present as diffuse multi-organ disease. Furthermore, lesions in different organs can present simultaneously or metachronously. In the pulmonary manefestations, lesions associated with IgG4-related disease have been described in the lung parenchyma, airways and pleura, as well as the mediastinum. We report a case of IgG4-related disease presenting as massive pleural effusion and thrombophlebitis.

키워드

참고문헌

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  3. Serosal involvement in IgG4-related disease: report of two cases and review of the literature vol.36, pp.7, 2014, https://doi.org/10.1007/s00296-016-3501-8
  4. Spontaneously Regressed Immunoglobulin IgG4-related Lung Disease Presenting as Multiple Cavitary Nodules vol.90, pp.5, 2014, https://doi.org/10.3904/kjm.2016.90.5.449
  5. IgG4-Related Lung Disease without Elevation of Serum IgG4 Level: A Case Report vol.79, pp.3, 2016, https://doi.org/10.4046/trd.2016.79.3.184
  6. Association of immunoglobulin G4 and free light chain with idiopathic pleural effusion vol.190, pp.1, 2017, https://doi.org/10.1111/cei.12999
  7. IgG4-related Pleuritis with Elevated Adenosine Deaminase in Pleural Effusion vol.57, pp.15, 2018, https://doi.org/10.2169/internalmedicine.0387-17
  8. IgG4-related lung disease on the horizon vol.18, pp.1, 2014, https://doi.org/10.2478/hkbrd-2018-0002
  9. Immunoglobulin G4-Related Disease Unilaterally Involving the Pulmonary Interstitium and Pleura: A Case Report vol.16, pp.1, 2014, https://doi.org/10.5812/iranjradiol.80281
  10. IgG4-related disease with elevated adenosine deaminase in pleural effusion diagnosed clinically using thoracoscopy under local anesthesia and FDG-PET-CT vol.30, pp.None, 2020, https://doi.org/10.1016/j.rmcr.2020.101066
  11. Mimickers of pulmonary lymphoma vol.37, pp.6, 2014, https://doi.org/10.1053/j.semdp.2020.05.002
  12. Refractory IgG4-related Pleural Disease with Chylothorax: A Case Report and Literature Review vol.60, pp.13, 2021, https://doi.org/10.2169/internalmedicine.6313-20
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